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ITO Koyu
Division of Molecular Physiological Chemistry

Researcher information

■ Degree
  • 博士 (医学), 北海道大学
■ Research Keyword
  • 自己免疫疾患
  • 細胞老化
  • cell adhesion
  • lymphatics
  • integrin
■ Field Of Study
  • Life sciences/Experimental pathology

Career

■ Career
  • Apr. 2025 - Present
    Shiga University of Medical Science, 生化学・分子生物学講座 分子生理化学部門, 准教授
  • Apr. 2023 - Mar. 2025
    Osaka University, 微生物病研究所遺伝子生物学分野, 特任助教
  • Apr. 2016 - Mar. 2023
    Tohoku University, Institute of Development, Aging and Cancer, 助教
  • Apr. 2014 - Mar. 2016
    Kyoto University, Graduate School of Medicine, 特定研究員
  • Apr. 2011 - Mar. 2014
    Hokkaido University, 特任助教

Research activity information

■ Paper
  • Targeted introduction of T cell receptor genes at the TRAC locus in cytotoxic T lymphocytes regenerated from human iPSCs by genome editing.
    Dil Afroza; Koji Terada; Koyu Ito; Md Abdul Jabbar Khan; Kenta Kondo; Kana Yamasaki; Seiji Nagano; Kyoko Masuda; Hiroshi Kawamoto; Yasutoshi Agata
    Biochemical and biophysical research communications, 14 May 2026
  • Senescence-like cells recruit γδ T cells to drive prolonged hyposmia after SARS-CoV-2 infection in mice.
    Shunya Tsuji; Sosuke Nakano; Koyu Ito; Shohei Minami; Ken Uemura; Yusuke Konishi; Masahiro Wakita; Yumiko Okumura; Shimpei Kawamoto; Akari Matsuki; Shinji Nakaoka; Chikako Ono; Hiroo Takahashi; Itsuki Anzai; Tokiko Watanabe; Akiyoshi Uezumi; Yoshiharu Matsuura; Takeshi Kobayashi; Toru Okamoto; Akio Tsuboi; Masataka Asagiri; Eiji Hara
    EMBO reports, 10 Apr. 2026
  • Reevaluating the senolytic activity of a GLS1 inhibitor and an anti-PD-1 antibody: toward greater reproducibility and methodological rigor.
    Shimpei Kawamoto; Haruki Horiguchi; Daisuke Torigoe; Masahiro Wakita; Koyu Ito; Sho Sugawara; Xiangyu Zhou; Takumi Mikawa; Jeong Hoon Park; Birte Kristin Jung; Yumiko Okumura; Hideka Miyagawa; Mikako Maruya; Nozomi Hori; Ken Uemura; Masataka Sugimoto; Michiyuki Matsuda; Naoki Mochizuki; Hiroshi Kondoh; Akiko Takahashi; Yuichi Oike; Eiji Hara
    EMBO reports, 03 Apr. 2026
  • Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance.
    Masahiro Wakita; Koyu Ito; Kaho Fujii; Dai Sakamoto; Takumi Mikawa; Sho Sugawara; Xiangyu Zhou; Jeong Hoon Park; Hideka Miyagawa; Daisuke Motooka; Emi Ogasawara; Naotada Ishihara; Akiko Takahashi; Hiroshi Kondoh; Eiji Hara
    Nature aging, Feb. 2026
  • Antibacterial properties of TiO2 layers formed by Au-sputtering and thermal oxidation of titanium under visible light
    T. Ueda; R. Koizumi; K. Ueda; K. Ito; K. Ogasawara; H. Kanetaka; T. Narushima
    J. Jpn. Inst. Metals and Mater., Dec. 2024, Refereed, Not invited
  • マウスモデルにおけるがん抗原の同定と難治性がんの克服
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕之; 小笠原 康悦; 宇高 恵子; 西村 泰治; 江藤 正俊
    日本癌治療学会学術集会抄録集, Oct. 2024
  • Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus
    Ken Yasaka; Tomohide Yamazaki; Hiroko Sato; Tsuyoshi Shirai; Minkwon Cho; Koji Ishida; Koyu Ito; Tetsuhiro Tanaka; Kouetsu Ogasawara; Hideo Harigae; Tomonori Ishii; Hiroshi Fujii
    Arthritis Research and Therapy, 01 Dec. 2023, Refereed
  • Visible-light-induced antibacterial activity of carbon and nitrogen co-doped rutile TiO2 films
    Ryusuke Koizumi; Kyosuke Ueda; Koyu Ito; Kouetsu Ogasawara; Hiroyasu Kanetaka; Takayuki Mokudai; Takayuki Narushima
    Thin Solid Films, 01 Sep. 2023, Refereed
  • Platelet αIIbβ3 integrin binds to SARS-CoV-2 spike protein of alpha strain but not wild type and omicron strains
    Koyu Ito; Kota Goto; Ryutaro Shirakawa; Hisanori Horiuchi; Kouetsu Ogasawara
    Biochemical and Biophysical Research Communications, 21 May 2023, Refereed
  • Antibacterial properties of TiO2 layers formed by Au-sputtering and thermal oxidation of titanium under visible light
    T. Ueda; R. Koizumi; K. Ueda; K. Ito; K. Ogasawara; H. Kanetaka; T. Narushima
    Mater. Trans., Jan. 2023, Refereed, Not invited
  • Diverse and divergent functions of IL-32β and IL-32γ isoforms in the regulation of malignant pleural mesothelioma cell growth and the production of VEGF-A and CXCL8
    Muneo Numasaki; Koyu Ito; Kiyoshi Takagi; Kengo Nagashima; Hirotsugu Notsuda; Hirokazu Ogino; Rika Ando; Yoshihisa Tomioka; Takashi Suzuki; Yoshinori Okada; Yasuhiko Nishioka; Michiaki Unno
    Cellular Immunology, 01 Nov. 2022, Refereed
  • 金属アレルギーの発症機序と予防・治療法の確立に向けた免疫学的解析
    伊藤 甲雄; 小笠原 康悦
    臨床免疫・アレルギー科, Dec. 2021
  • VEGF-A, HGF and bFGF are Involved in IL-17A-mediated Migration and Capillary-like Vessel Formation of Vascular Endothelial Cells.
    Muneo Numasaki; Koyu Ito
    Iranian journal of immunology : IJI, Jun. 2021
  • 肺移植後閉塞性細気管支炎進展におけるNK細胞の役割 マウス異所性気管移植モデルを用いて
    川上 徹; 伊藤 甲雄; 松田 安史; 野田 雅史; 桜田 晃; 星川 康; 岡田 克典; 小笠原 康悦
    移植, Mar. 2021
  • Formation of carbon-added anatase-rich TiO2 layers on titanium and their antibacterial properties in visible light.
    Takatoshi Ueda; Naoki Sato; Ryusuke Koizumi; Kyosuke Ueda; Koyu Ito; Kouetsu Ogasawara; Takayuki Narushima
    Dental materials : official publication of the Academy of Dental Materials, Feb. 2021
  • Palladium-Induced Temporal Internalization of MHC Class I Contributes to T Cell-Mediated Antigenicity.
    Koyu Ito; Takayuki Kanaseki; Serina Tokita; Toshihiko Torigoe; Noriyasu Hirasawa; Kouetsu Ogasawara
    Frontiers in immunology, 2021
  • Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses.
    Masato Kosuge; Emi Furusawa-Nishii; Koyu Ito; Yoshiro Saito; Kouetsu Ogasawara
    Scientific reports, 20 Oct. 2020
  • 【口腔環境と全身のクロストーク】歯科金属アレルギーの予防・診断・治療に向けた疾患特異的T細胞の同定
    伊藤 甲雄; 武田 裕利; 小笠原 康悦
    炎症と免疫, Oct. 2019
  • COX-2 Induces T cell accumulation and IFN-γ production during the development of chromium allergy
    R. Sitalaksmi; K. Ito; K. Ogasawara; Y. Suto; M. Itabashi; K. Ueda; N. Hirasawa; T. Narushima; S. Higuchi; N. Sato; N. Hendrijantini; U. Kresnoadi; K. Sasaki
    Autoimmunity, Aug. 2019, Refereed, Not invited
  • Visible-light-responsive antibacterial activity of Au-incorporated TiO2 layers formed on Ti-(0-10)at%Au alloys by air oxidation.
    Takatoshi Ueda; Kyosuke Ueda; Koyu Ito; Kouetsu Ogasawara; Hiroyasu Kanetaka; Takayuki Mokudai; Yoshimi Niwano; Takayuki Narushima
    Journal of biomedical materials research. Part A, May 2019, Refereed, Not invited
  • Cytotoxicity of Natural Killer Cells Activated Through NKG2D Contributes to the Development of Bronchiolitis Obliterans in a Murine Heterotopic Tracheal Transplant Model
    T. Kawakami; K. Ito; Y. Matsuda; M. Noda; A. Sakurada; Y. Hoshikawa; Y. Okada; K. Ogasawara
    AMERICAN JOURNAL OF TRANSPLANTATION, Sep. 2017, Refereed, Not invited
  • TRAV7-2*02 Expressing CD8⁺ T Cells Are Responsible for Palladium Allergy.
    Yuri Takeda; Yoshiko Suto; Koyu Ito; Wataru Hashimoto; Tadashi Nishiya; Kyosuke Ueda; Takayuki Narushima; Tetsu Takahashi; Kouetsu Ogasawara
    International journal of molecular sciences, 31 May 2017, Refereed, Not invited
  • The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine.
    Koyu Ito; Akira Nakajima; Yuji Fukushima; Keiichiro Suzuki; Keiko Sakamoto; Yoko Hamazaki; Kouetsu Ogasawara; Nagahiro Minato; Masakazu Hattori
    PloS one, 2017, Refereed, Not invited
  • Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice.
    Keiko Sakamoto; Yuji Fukushima; Koyu Ito; Michiyuki Matsuda; Shigekazu Nagata; Nagahiro Minato; Masakazu Hattori
    Journal of immunology (Baltimore, Md. : 1950), 15 Sep. 2016, Refereed, Not invited
  • Syndecan 4 Regulation of the Development of Autoimmune Arthritis in Mice by Modulating B Cell Migration and Germinal Center Formation.
    Tsutomu Endo; Koyu Ito; Junko Morimoto; Masashi Kanayama; Daichi Ota; Masahiro Ikesue; Shigeyuki Kon; Daisuke Takahashi; Tomohiro Onodera; Norimasa Iwasaki; Toshimitsu Uede
    Arthritis & rheumatology (Hoboken, N.J.), Sep. 2015, Refereed, Not invited
  • Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts.
    Daichi Ota; Masashi Kanayama; Yutaka Matsui; Koyu Ito; Naoyoshi Maeda; Goro Kutomi; Koichi Hirata; Toshihiko Torigoe; Noriyuki Sato; Akinori Takaoka; Ann F Chambers; Junko Morimoto; Toshimitsu Uede
    Journal of molecular medicine (Berlin, Germany), Dec. 2014, Refereed, Not invited
  • Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress.
    Koyu Ito; Junko Morimoto; Akio Kihara; Yutaka Matsui; Daisuke Kurotaki; Masashi Kanayama; Szandor Simmons; Masaru Ishii; Dean Sheppard; Akinori Takaoka; Toshimitsu Uede
    Proceedings of the National Academy of Sciences of the United States of America, 25 Feb. 2014, Refereed, Not invited
  • A novel cryptic binding motif, LRSKSRSFQVSDEQY, in the C-terminal fragment of MMP-3/7-cleaved osteopontin as a novel ligand for α9β1 integrin is involved in the anti-type II collagen antibody-induced arthritis.
    Shigeyuki Kon; Yosuke Nakayama; Naoki Matsumoto; Koyu Ito; Masashi Kanayama; Chiemi Kimura; Hitomi Kouro; Dai Ashitomi; Tadashi Matsuda; Toshimitsu Uede
    PloS one, 2014, Refereed, Not invited
  • The cell to cell interaction of breast cancer cells regulates cancer invasion via adam15
    Daichi Ota; Masahiro Ikesue; Yutaka Matsui; Koyu Ito; Yoshikazu Takada; Ann F. Chambers; Toshimitsu Uede
    American Journal of Immunology, 17 Oct. 2012, Refereed, Not invited
  • Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice.
    Keiko Danzaki; Yutaka Matsui; Masahiro Ikesue; Daichi Ohta; Koyu Ito; Masashi Kanayama; Daisuke Kurotaki; Junko Morimoto; Yoichiro Iwakura; Hideo Yagita; Hiroyuki Tsutsui; Toshimitsu Uede
    Arteriosclerosis, thrombosis, and vascular biology, Feb. 2012, Refereed, Not invited
  • ATM-mediated DNA damage signals mediate immune escape through integrin-αvβ3-dependent mechanisms.
    Masahisa Jinushi; Shigeki Chiba; Muhammad Baghdadi; Ichiro Kinoshita; Hirotoshi Dosaka-Akita; Koyu Ito; Hironori Yoshiyama; Hideo Yagita; Toshimitsu Uede; Akinori Takaoka
    Cancer research, 01 Jan. 2012, Refereed, Not invited
  • α9β1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation.
    Masashi Kanayama; Junko Morimoto; Yutaka Matsui; Masahiro Ikesue; Keiko Danzaki; Daisuke Kurotaki; Koyu Ito; Toshimichi Yoshida; Toshimitsu Uede
    Journal of immunology (Baltimore, Md. : 1950), 01 Dec. 2011, Refereed, Not invited
  • Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization.
    Masahiro Ikesue; Yutaka Matsui; Daichi Ohta; Keiko Danzaki; Koyu Ito; Masashi Kanayama; Daisuke Kurotaki; Junko Morimoto; Tetsuhito Kojima; Hiroyuki Tsutsui; Toshimitsu Uede
    Arteriosclerosis, thrombosis, and vascular biology, May 2011, Refereed, Not invited
  • CSF-1-dependent red pulp macrophages regulate CD4 T cell responses.
    Daisuke Kurotaki; Shigeyuki Kon; Kyeonghwa Bae; Koyu Ito; Yutaka Matsui; Yosuke Nakayama; Masashi Kanayama; Chiemi Kimura; Yoshinori Narita; Takashi Nishimura; Kazuya Iwabuchi; Matthias Mack; Nico van Rooijen; Shimon Sakaguchi; Toshimitsu Uede; Junko Morimoto
    Journal of immunology (Baltimore, Md. : 1950), 15 Feb. 2011, Refereed, Not invited
  • Osteopontin is involved in migration of eosinophils in asthma
    A. Takahashi; M. Kurokawa; S. Konno; K. Ito; S. Kon; S. Ashino; T. Nishimura; T. Uede; N. Hizawa; S. K. Huang; M. Nishimura
    Clinical and Experimental Allergy, Aug. 2009, Refereed, Not invited
  • Alpha9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis.
    Masashi Kanayama; Daisuke Kurotaki; Junko Morimoto; Tsuyoshi Asano; Yutaka Matsui; Yosuke Nakayama; Yoshinari Saito; Koyu Ito; Chiemi Kimura; Norimasa Iwasaki; Koji Suzuki; Tanenobu Harada; Hong Mei Li; Jun Uehara; Tadaaki Miyazaki; Akio Minami; Shigeyuki Kon; Toshimitsu Uede
    Journal of immunology (Baltimore, Md. : 1950), 15 Jun. 2009, Refereed, Not invited
  • The differential amino acid requirement within osteopontin in alpha4 and alpha9 integrin-mediated cell binding and migration.
    Koyu Ito; Shigeyuki Kon; Yosuke Nakayama; Daisuke Kurotaki; Yoshinari Saito; Masashi Kanayama; Chiemi Kimura; Hongyan Diao; Junko Morimoto; Yutaka Matsui; Toshimitsu Uede
    Matrix biology : journal of the International Society for Matrix Biology, Jan. 2009, Refereed, Not invited
  • Osteopontin small interfering RNA protects mice from fulminant hepatitis.
    Yoshinari Saito; Shigeyuki Kon; Yukio Fujiwara; Yosuke Nakayama; Daisuke Kurotaki; Naoki Fukuda; Chiemi Kimura; Masashi Kanayama; Koyu Ito; Hongyan Diao; Yutaka Matsui; Yasuo Komatsu; Eiko Ohtsuka; Toshimitsu Uede
    Human gene therapy, Dec. 2007, Refereed, Not invited
■ MISC
  • がん抗原免疫を軸とした治療抵抗性を克服するための遺伝子解析と基礎研究
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕之; 小笠原 康悦; 宇高 恵子; 西村 泰治; 江藤 正俊
    西日本泌尿器科学会総会抄録集, Nov. 2023
  • マウスモデルにおけるIn silico解析を用いた新規がん抗原の同定と難治性がんの克服
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕之; 小笠原 康悦; 宇高 恵子; 江藤 正俊; 西村 泰治
    日本がん免疫学会総会プログラム・抄録集, Jun. 2023
  • Antibacterial Properties of TiO2 Layers Formed by Au-Sputtering and Thermal Oxidation of Titanium under Visible Light
    Ueda Takatoshi; Koizumi Ryusuke; Ueda Kyosuke; Ito Koyu; Ogasawara Kouetsu; Kanetaka Hiroyasu; Narushima Takayuki
    Materials Transactions (Web), 2023
  • 腫瘍抗原ワクチンにより増強される難治性がんに対する免疫チェックポイント阻害剤の抗腫瘍効果(Tumor antigen vaccine enhances anti-tumor effects of Immune checkpoint inhibitors against refractory cancers.)
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕之; 小笠原 康悦; 宇高 恵子; 西村 泰治; 江藤 正俊
    西日本泌尿器科学会総会抄録集, Nov. 2022
  • 腫瘍関連抗原の能動免疫による難治性がんの克服(Tumor associated antigen vaccine enhances anti-tumor effects of immune checkpoint inhibitors against refractory cancers.)
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕幸; 小笠原 康悦; 宇高 恵子; 江藤 正俊; 西村 泰治
    日本癌学会総会記事, Sep. 2022
  • マウスモデルにおけるIn silico解析を用いた新規がん抗原の同定と難治性がんの克服
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕之; 小笠原 康悦; 宇高 恵子; 江藤 正俊; 西村 泰治
    日本がん免疫学会総会プログラム・抄録集, Jun. 2022
  • マウスモデルにおける全遺伝子網羅的なIn silicoアルゴリズムによる新規がん抗原の同定と難治性膀胱がんの克服
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 岸 裕之; 小笠原 康悦; 宇高 恵子; 西村 泰治; 江藤 正俊
    西日本泌尿器科学会総会抄録集, Nov. 2021
  • 腫瘍関連抗原の能動免疫と免疫チェックポイント阻害剤の併用による難治性がんの克服
    上田 翔平; 牛島 美保; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 小笠原 康悦; 岸 裕幸; 江藤 正俊; 西村 泰治
    日本癌学会総会記事, Sep. 2021
  • マウス難治性癌モデルにおける腫瘍抗原ペプチドワクチン療法と免疫チェックポイント阻害剤の併用療法の奏効
    上田 翔平; 入江 厚; 千住 覚; 伊藤 甲雄; 浜名 洋; 小笠原 康悦; 岸 裕幸; 江藤 正俊; 西村 泰治
    日本癌学会総会記事, Oct. 2020
  • Au蒸着Ti基板の大気酸化によるAu添加TiO2膜の作製およびその可視光誘起抗菌能
    上田隆統志; 佐藤直生; 上田恭介; 伊藤甲雄; 小笠原康悦; 目代貴之; 金高弘恭; 成島尚之
    日本金属学会講演概要(CD-ROM), 2019
  • Ti-Au合金表面に作製したAu添加TiO2膜の可視光照射下における抗菌能
    上田隆統志; 上田恭介; 伊藤甲雄; 小笠原康悦; 金高弘恭; 目代貴之; 目代貴之; 庭野吉己; 庭野吉己; 成島尚之
    日本防菌防黴学会年次大会要旨集, 2019
  • 大気酸化によりTi‐Au合金表面に作製したTiO2膜の可視光照射下における抗菌能およびラジカル生成
    上田隆統志; 上田恭介; 伊藤甲雄; 小笠原康悦; 目代貴之; 金高弘恭; 庭野吉己; 成島尚之
    日本金属学会講演概要(CD-ROM), 05 Mar. 2018, Not refereed, Not invited
    http://jglobal.jst.go.jp/public/201802272553706023
  • 大気酸化によりTi-Au合金表面に作製したTiO2膜の可視光照射下における抗菌能およびラジカル生成
    上田隆統志; 上田恭介; 伊藤甲雄; 小笠原康悦; 目代貴之; 金高弘恭; 庭野吉己; 成島尚之
    日本金属学会講演概要(CD-ROM), 2018
  • 学術奨励賞・受賞記念論文 Syndecan-4 regulates development of autoimmune arthritis by modulating B cell migration and germinal center formation : 自己免疫性関節炎におけるシンデカン-4の機能解析
    遠藤 努; 伊藤 甲雄; 森本 純子; 金山 剛士; 太田 大地; 池末 昌弘; 今 重之; 小野寺 智洋; 高橋 大介; 岩崎 倫政; 上出 利光
    北海道整形災害外科学会雑誌 : 北海道整形災害外科学会機関誌, Aug. 2017, Not refereed, Not invited
  • Ag含有非晶質リン酸カルシウムコーティングによる硬組織代替デバイスへの抗菌性と骨形成能の付与
    上田 恭介; 井上 紅花; 伊藤 甲雄; 小笠原 康悦; 成島 尚之
    日本骨形態計測学会雑誌, May 2017, Not refereed, Not invited
  • Role of α9 integrin in intractable autoimmune diseases
    伊藤 甲雄; 上出 利光
    医学のあゆみ, 15 Feb. 2014
  • The role of syndecan-4 in the development of rheumatoid arthritis
    Tsutomu Endo; Junko Morimoto; Koyu Ito; Norimasa Iwasaki; Toshimitsu Uede
    JOURNAL OF IMMUNOLOGY, May 2013, Not refereed, Not invited
  • Integrin alpha 9 on lymphatic endothelial cell at draining lymph node regulates lymphocyte egress via controlling S1P secretion during inflammation (P5114)
    Koyu Ito; Junko Morimoto; Akio Kihara; Szandor Simmons; Masaru Ishii; Toshimitsu Uede
    JOURNAL OF IMMUNOLOGY, May 2013, Not refereed, Not invited
  • 乳癌の増殖および転移におけるα9β1インテグリンとマトリセルラータンパク質の相互作用の機能解析
    太田大地; 金山剛士; 松井裕; 伊藤甲雄; 前田直良; 上出利光
    日本分子生物学会年会プログラム・要旨集(Web), 2013
  • The role of Syndecan-4 in the development of rheumatoid arthritis
    Tsutomu Endo; Junko Morimoto; Koyu Ito; Masashi Kanayama; Norimasa Iwasaki; Akio Minami; Toshimitsu Uede
    JOURNAL OF IMMUNOLOGY, May 2012, Not refereed, Not invited
  • 関節リウマチにおけるsyndecan-4の関与
    遠藤努; 森本純子; 伊藤甲雄; 金山剛士; 岩崎倫政; 三浪明男; 上出利光
    日本整形外科学会雑誌, 2012
  • Interaction of alpha 9 integrin on medullary sinus with its ligand regulates lymphocyte egress via regulating S1P transporter, Spns2 expression and subsequent S1P secretion under inflammatory condition
    Koyu Ito; Yutaka Matsui; Daisuke Kurotaki; Junko Morimoto; Akio Kihara; Toshimitsu Uede
    JOURNAL OF IMMUNOLOGY, Apr. 2011, Not refereed, Not invited
  • 赤脾髄固着マクロファージによるT細胞免疫応答制御機構の解明
    黒滝大翼; 森本純子; BAE Kyeonghwa; 伊藤甲雄; 金山剛士; 松井裕; 上出利光
    日本病理学会会誌, 2010
  • 気管支喘息におけるオステオポンチン(OPN)と好酸球性気道炎症の関連
    高橋歩; 今野哲; 黒川真嗣; 檜澤伸之; 伊藤甲雄; 今重之; 芦野滋; 前田由起子; 伊佐田朗; 服部健史; 西村隆司; 上出利光; HUANG Shau-Ku; 西村正治
    アレルギー, 2008
■ Affiliated academic society
  • Mar. 2025, Present
    日本癌学会
  • Jun. 2024, Present
    日本分子生物学会
  • May 2009, Present
    JAPANESE SOCIETY FOR IMMUNOLOGY (JSI)
■ Research Themes
  • 胸腺外新規Aire発現細胞群による癌のリンパ節転移における免疫抑制環境の構築
    基盤研究(C)
    東北大学
    01 Apr. 2022, 31 Mar. 2025
  • Materials surface design to inactivate coronaviruses by focusing on spike proteins
    Grant-in-Aid for Scientific Research (A)
    Tohoku University
    05 Apr. 2021, 31 Mar. 2025
  • Contribution of LFA-1 integrin in T cell trogocytosis
    Grant-in-Aid for Scientific Research (C)
    Tohoku University
    01 Apr. 2019, 31 Mar. 2022
  • The role of Opn-expressing CD8 T cells in the intestine
    Grant-in-Aid for Young Scientists (B)
    01 Apr. 2015, 31 Mar. 2017