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ASAHINA Kinji
Central Research Laboratory

Contact Pointasahinabelle.shiga-med.ac.jp

Researcher information

■ Degree
  • Ph.D., Hiroshima University, Mar. 1999
■ Research Keyword
  • Liver
  • Hepatic stellate cells
  • Mesothelial cells
  • Macrophages
  • Fibrosis
  • Regeneration
  • Developmental biology
  • Stem cells
  • Pancreas
  • Pancreatic cancer
■ Field Of Study
  • Life sciences/Morphology, anatomy
  • Life sciences/Developmental biology
  • Life sciences/Pathobiochemistry

Career

■ Career
  • Aug. 2021 - Present
    Shiga University of Medical Science, Central Research Laboratory, Associate Professor
  • Feb. 2014 - Jul. 2021
    University of Southern California, Keck School of Medicine, Associate Professor
  • Apr. 2008 - Jan. 2014
    University of Southern California, Keck School of Medicine, Assistant Professor
  • Jan. 2007 - Mar. 2008
    University of Southern California, Keck School of Medicine, Visiting Research Scientist, Assistant Professor
  • Apr. 2002 - Jan. 2007
    Tokyo Medical and Dental University, Medical Research Institute, Assistant Professor
  • Apr. 1999 - Mar. 2002
    Hiroshima Prefectural Institute of Industrial Science and Technology, 科学技術振興事業団 広島県組織再生プロジェクト, Research fellow
  • Apr. 1997 - Mar. 1998
    Hiroshima University, Faculty of Science, Teaching assistant
■ Educational Background
  • Apr. 1994 - Mar. 1999
    Hiroshima University, Graduate School of Science, 生物科学
  • Apr. 1990 - Mar. 1994
    Shimane University, 理学部, 生物学科
■ Member History
  • 2025, Present
    Committee member, Shiga University of Medical Science, JD program
  • 2024, Present
    Radiation protection supervisor, Shiga University of Medical Science
  • 2024, Present
    International center, Shiga University of Medical Science
  • 2024, Present
    Admission Center, Shiga University of Medical Science
  • 2024, Present
    Board member, Hepatic Sinusoidal Research Japan
  • 2023, Present
    Harassment counselor, Shiga University of Medical Science
  • 2023, Present
    Member, MRI network
  • 2023, Present
    Hepatology, Editorial board member
  • 2022, Present
    Board member, The Japanese society for the research of hepatic cells
  • 2021, Present
    Biosafety, Shiga University of Medical Science
  • 2021, Present
    Genetic modification safety committee, Shiga University of Medical Science
  • 2021, Present
    Frontiers in Cell and Developmental Biology, Editorial Board Member
  • 2019, Present
    Scientific Reports, Editor
  • 2022, 2025
    Frontier in Immunology, Topic editor
  • 2020, 2022
    Liver fibrosis SIG member, AASLD
  • 2022
    NIH/NIAAA, AA-1 grant reviewer
  • 2020, 2021
    Course Coordinator, Methods in Cellular and Clinical Pathology (PATH 553), University of Southern California
  • 2020, 2021
    Committee member, Experimental and Molecular Pathology Degree Program, University of Southern California
  • 2019, 2021
    Member of the IACUC committee, University of Southern California
  • 2019, 2021
    Director, Cell and Tissue Imaging Core, USC Research Center for Liver Diseases
  • 2017, 2021
    Executive Committee member, Southern California Research Center for ALPD & Cirrhosis
  • 2016, 2021
    NIH/NIAAA, ZAA1-(32) grant reviewer
  • 2016, 2021
    Full Member of the Epigenetics and Regulation Program, USC Norris Comprehensive Cancer Center
  • 2013, 2021
    Course coordinator for Pathology 575: Frontiers of Pathology, Cellular Homeostasis Lecture Series, University of Southern California
  • 2011, 2021
    Associate Member, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC
  • 2010, 2021
    Member, University of Southern California Liver Center
  • 2009, 2021
    Codirector, Non-Parenchymal Core, Southern California Research Center for ALPD & Cirrhosis
  • 2007, 2021
    Member, Southern California Research Center for ALPD & Cirrhosis
  • 2021
    Course coordinator, Cellular Homeostasis Lecture Series (INTD 570), University of Southern California
  • 2021
    Course Coordinator, Methods in Cellular and Clinical Pathology (PATH 554), University of Southern California
  • 2021
    Committee member of PhD oral qualifying exam, School of Pharmacy, University of Southern California
  • 2021
    Committee member of evaluation of faculty graduate student teaching, Department of Pathology, Keck School of Medicine, University of Southern California
  • 2017, 2020
    USC Dean's Pilot Funding Program, reviewer
  • 2014, 2019
    MRC Research Grant, reviewer
  • 2015, 2018
    Faculty member, Liver biology and pathology section, F1000Prime
  • 2015
    MRC Clinical Research Training Fellowship, grant reviewer
  • 2015
    NIH/NIGMS, ZGM1 RCB-3 (C3) grant reviewer

Research activity information

■ Award
  • 2020
    University of Southern California, Student recognition award (Kaitlin Skrypek)
  • 2020
    University of Southern California, Robert S. Cleland Teaching Award
    Kinji Asahina
  • 2019
    American Association for the Study of Liver Diseases (AASLD) fellow
    Kinji Asahina
  • 2018
    University of Southern California, Student Opportunities for Academic Research Award (Emily Wan)
  • 2017
    University of Southern California, Dornsife Summer Undergraduate Research fund (Emily Wan)
  • 2017
    Southern California Research Center for ALPD, Lee Summer Research Fellowship (Emily Wan)
  • 2016
    19th Annual Pathology Conference of USC, Best oral presentation (Ingrid Lua)
  • 2016
    Department of Pathology, USC, Student of the year (Ingrid Lua)
  • 2015
    18th Annual Pathology Conference, USC, Best research paper award (Ingrid Lua)
  • 2015
    10th International symposium on alcoholic liver and pancreatic diseases and cirrhosis, Travel award (Ingrid Lua)
  • 2015
    Southern California Research Center for ALPD, Lee Summer Research Fellowship (Shadi Razipour)
  • 2015
    18th International society for hepatic sinusoidal research meeting, Travel award (Ingrid Lua)
  • 2015
    AASLD liver meeting, Denoted AASLD Presidential Poster of Distinction
    Kinji Asahina
  • 2013
    16th Annual Pathology Conference, USC, 2nd, Best paper award (Yuchang Li)
  • 2013
    F1000 Prime, Evaluated PNAS 2013;110:2324-2329 by
    Kinji Asahina
  • 2012
    7th International Symposium on ALPD and Cirrhosis, Travel award (Yuchang Li)
  • 2011
    6th International Symposium on ALPD and Cirrhosis, Best poster award
    Kinji Asahina
  • 2009
    F1000 Prime, Evaluated Hepatology 2009;49:998-1011 by
    Kinji Asahina
  • 2004
    Cytoprotection, Encouraging award (Yuji Kumashiro)
  • 2004
    Japanese Society for regenerative medicine, Best presentation, 3rd annual meeting
    Kinji Asahina
■ Paper
  • Structure and thickness of Glisson's capsule differ considerably on the liver surface in mammalian species.
    Hiroki Uchida; Naoyuki Aihara; Toshifumi Morimura; Shoma Matsumoto; Daichi Hasegawa; Tomoko Ichiki; Eiichi Okamura; Masanaga Muto; Go Sugahara; Toshio Miki; Masatsugu Ema; Kenichi Watanabe; Junichi Kamiie; Kinji Asahina
    Anatomical Record, 2025, Refereed, Corresponding
  • Recruitment of large peritoneal macrophages to capsular fibrosis developed on the liver surface
    Steven Balog; Soi Jeong; Kinji Asahina
    FASEB Journal, 2024, Refereed, Not invited, Corresponding
  • Mesenchymal and immune cell crosstalk in fibrotic diseases.
    Kinji Asahina; Subburaj Ilangumaran
    Frontiers in Immunology, Oct. 2023, Refereed, Not invited
  • Heterozygous midnolin knockout attenuates severity of nonalcoholic fatty liver disease in mice fed a Western-style diet high in fat, cholesterol, and fructose.
    Soo-Mi Kweon; Jose Irimia-Dominguez; Gayeoun Kim; Patrick T Fueger; Kinji Asahina; Keith K Lai; Daniela S Allende; Quincy R Lai; Chih-Hong Lou; Walter M Tsark; Ju Dong Yang; Dominic S Ng; Ju-Seog Lee; Patrick Tso; Wendong Huang; Keane K Y Lai
    American Journal of Physiology. Gastrointestinal and Liver Physiology, Aug. 2023, Refereed
  • Prominin-1 promotes restitution of the murine extrahepatic biliary epithelium following cholestatic liver injury
    Allen Zhong; Celia Short; Jiabo Xu; Esteban Fernandez; Nicolas Malkoff; Nicolas Noriega; Theresa Yeo; Larry Wang; Nirmala Mavila; Kinji Asahina; Kasper S. Wang
    Hepatology Communications, 2023, Refereed
  • TWEAK/FN14 promotes profibrogenic pathway activation in Prominin-1-expressing hepatic progenitor cells in biliary atresia
    Celia Short; Allen Zhong; Jiabo Xu; Ella Mahdi; Alison Glazier; Nicolas Malkoff; Nicolas Noriega; Theresa Yeo; Kinji Asahina; Kasper Wang
    Hepatology, 2023, Refereed
  • Emergence of highly profibrotic and proinflammatory Lrat+ Fbln2+ HSC subpopulation in alcoholic hepatitis.
    Steven Balog; Reika Fujiwara; Stephanie Q Pan; Khairat B El-Baradie; Hye Yeon Choi; Sonal Sinha; Qihong Yang; Kinji Asahina; Yibu Chen; Meng Li; Matthew Salomon; Stanley W-K Ng; Hidekazu Tsukamoto
    Hepatology, 2023, Refereed
  • TAZ/WWTR1 mediates liver mesothelial–mesenchymal transition induced by stiff extracellular environment, TGF‐β1, and lysophosphatidic acid
    Ingrid Lua; Steven Balog; Kinji Asahina
    Journal of Cellular Physiology, May 2022, Refereed, Corresponding
  • Induction of Cell Death in Pancreatic Tumors by Zinc and Its Fluorescence Chelator TSQ
    Kinji Asahina
    Biological Trace Element Research, Apr. 2022, Refereed, Corresponding
  • Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling
    Joel Zindel; Jonas Mittner; Julia Bayer; Simon L. April-Monn; Andreas Kohler; Ysbrand Nusse; Michel Dosch; Isabel Büchi; Daniel Sanchez-Taltavull; Heather Dawson; Mercedes Gomez de Agüero; Kinji Asahina; Paul Kubes; Andrew J. Macpherson; Deborah Stroka; Daniel Candinas
    Nature Communications, Dec. 2021, Refereed
  • Loss of lysophosphatidic acid receptor 1 in hepatocytes reduces steatosis via down-regulation of CD36
    Ingrid Lua; Steven Balog; Ami Yanagi; Chise Tateno; Kinji Asahina
    Prostaglandins & Other Lipid Mediators, Oct. 2021, Refereed, Corresponding
  • Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease
    Yuchang Li; Liting Chen; Lu Li; Chantal Sottas; Stephanie K. Petrillo; Anthoula Lazaris; Peter Metrakos; Hangyu Wu; Yuji Ishida; Takeshi Saito; Lucy Golden-Mason; Hugo R. Rosen; Jeremy J. Wolff; Cristina I. Silvescu; Samuel Garza; Garett Cheung; Tiffany Huang; Jinjiang Fan; Martine Culty; Bangyan Stiles; Kinji Asahina; Vassilios Papadopoulos
    iScience, May 2021, Refereed
  • Urea-based amino sugar agent clears murine liver and preserves protein fluorescence and lipophilic dyes
    Michelle Hough; Michael Fenlon; Alison Glazier; Celia Short; Gerardo Esteban Fernandez; Jiabo Xu; Elaa Mahdi; Kinji Asahina; Kasper S Wang
    BioTechniques, Feb. 2021, Refereed
  • Inhibition of Stearoyl-CoA Desaturase Induces the Unfolded Protein Response in Pancreatic Tumors and Suppresses Their Growth
    Kaitlin Skrypek; Steven Balog; Yoshihiro Eriguchi; Kinji Asahina
    Pancreas, Feb. 2021, Refereed, Corresponding
  • Prominin‐1‐expressing hepatic progenitor cells induce fibrogenesis in murine cholestatic liver injury
    Michael Fenlon; Celia Short; Jiabo Xu; Nicolas Malkoff; Elaa Mahdi; Michelle Hough; Alison Glazier; Calvin Lee; Kinji Asahina; Kasper S. Wang
    Physiological Reports, Jul. 2020, Refereed
  • Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras
    Kinji Asahina; Steven Balog; Edward Hwang; Eugene Moon; Emily Wan; Kaitlin Skrypek; Yibu Chen; Jay Fernandez; Janet Romo; Qihong Yang; Keane Lai; Samuel W. French; Hidekazu Tsukamoto
    American Journal of Physiology-Gastrointestinal and Liver Physiology, 01 Feb. 2020, Refereed
  • Development of Capsular Fibrosis Beneath the Liver Surface in Humans and Mice
    Steven Balog; Yuchang Li; Tomohiro Ogawa; Toshio Miki; Takeshi Saito; Samuel W. French; Kinji Asahina
    Hepatology, Jan. 2020, Refereed, Corresponding
  • Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers
    Tomohiro Ogawa; Yuchang Li; Ingrid Lua; Andrea Hartner; Kinji Asahina
    Developmental Dynamics, Jun. 2018, Refereed, Corresponding
  • Hepatic Prominin-1 expression is associated with biliary fibrosis
    Marie V. Nguyen; Jessica A. Zagory; William H. Dietz; Alex Park; Michael Fenlon; Menghan Zhao; Jiabo Xu; Ingrid Lua; Nirmala Mavila; Kinji Asahina; Kasper S. Wang
    Surgery, May 2017, Refereed
  • Activation of hepatic stellate cell in Pten null liver injury model
    Lina He; James Gubbins; Zhechu Peng; Vivian Medina; Fan Fei; Kinji Asahina; Jiaohong Wang; Michael Kahn; Carl B. Rountree; Bangyan L. Stiles
    Fibrogenesis & Tissue Repair, Dec. 2016, Refereed
  • Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers
    Ingrid Lua; Yuchang Li; Jessica A. Zagory; Kasper S. Wang; Samuel W. French; Jean Sévigny; Kinji Asahina
    Journal of Hepatology, May 2016, Refereed, Corresponding
  • The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration
    Ingrid Lua; Kinji Asahina
    Gut and Liver, 23 Mar. 2016, Refereed, Invited, Corresponding
  • Role of TGF-β signaling in differentiation of mesothelial cells to vitamin A-poor hepatic stellate cells in liver fibrosis
    Yuchang Li; Ingrid Lua; Samuel W. French; Kinji Asahina
    American Journal of Physiology-Gastrointestinal and Liver Physiology, 15 Feb. 2016, Refereed, Corresponding
  • Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis
    Ingrid Lua; Yuchang Li; Lamioko S. Pappoe; Kinji Asahina
    American Journal of Pathology, Dec. 2015, Refereed, Corresponding
  • MACS isolation and culture of mouse liver mesothelial cells.
    Yuchang Li; Ingrid Lua; Kinji Asahina.
    Bio-protocol, Jul. 2015, Refereed, Invited, Corresponding
  • Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia
    Nirmala Mavila; David James; Pranavkumar Shivakumar; Marie V. Nguyen; Sarah Utley; Katrina Mak; Allison Wu; Shengmei Zhou; Larry Wang; Christopher Vendyres; Megan Groff; Kinji Asahina; Kasper S. Wang
    Hepatology, Sep. 2014, Refereed
  • TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis
    Sayaka Inokuchi-Shimizu; Eek Joong Park; Yoon Seok Roh; Ling Yang; Bi Zhang; Jingyi Song; Shuang Liang; Michael Pimienta; Koji Taniguchi; Xuefeng Wu; Kinji Asahina; William Lagakos; Mason R. Mackey; Shizuo Akira; Mark H. Ellisman; Dorothy D. Sears; Jerrold M. Olefsky; Michael Karin; David A. Brenner; Ekihiro Seki
    Journal of Clinical Investigation, 01 Aug. 2014, Refereed
  • Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury
    Ingrid Lua; David James; Jiaohong Wang; Kasper S. Wang; Kinji Asahina
    Hepatology, Jul. 2014, Refereed, Corresponding
  • Hepatic stellate cells in liver development, regeneration, and cancer
    Chunyue Yin; Kimberley J. Evason; Kinji Asahina; Didier Y.R. Stainier
    Journal of Clinical Investigation, 01 May 2013, Refereed
  • Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial–mesenchymal transition in liver injury
    Yuchang Li; Jiaohong Wang; Kinji Asahina
    Proceedings of the National Academy of Sciences of the United States of America, 05 Feb. 2013, Refereed, Corresponding, URL
  • Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator-activated receptor γ in hepatic stellate cells for their antifibrotic effect
    Melissa D. Yang; Yi-Ming Chiang; Reiichi Higashiyama; Kinji Asahina; Derek A. Mann; Jelena Mann; Clay C.C. Wang; Hidekazu Tsukamoto
    Hepatology, Apr. 2012, Refereed
  • Hepatic Stellate Cell-derived Delta-like Homolog 1 (DLK1) Protein in Liver Regeneration
    Nian-Ling Zhu; Kinji Asahina; Jiaohong Wang; Akiko Ueno; Raul Lazaro; Yuichiro Miyaoka; Atsushi Miyajima; Hidekazu Tsukamoto
    Journal of Biological Chemistry, Mar. 2012, Refereed, URL
  • Morphogens and hepatic stellate cell fate regulation in chronic liver disease
    Hidekazu Tsukamoto; Nian-Ling Zhu; Jiaohong Wang; Kinji Asahina; Keigo Machida
    Journal of Gastroenterology and Hepatology, Mar. 2012, Refereed, URL
  • Hepatic stellate cells mediate differentiation of dendritic cells from monocytes
    Rie Ozeki; Sei Kakinuma; Kinji Asahina; Keiko Shimizu-Saito; Shigeki Arii; Yujiro Tanaka; Hirobumi Teraoka.
    J Med Dent Sci, Mar. 2012, Refereed
  • Hepatic stellate cell progenitor cells
    Kinji Asahina.
    J Gastroenterol Hepatol, Mar. 2012, Not refereed, Invited, URL
  • Epigenetic cell fate regulation of hepatic stellate cells
    Hidekazu Tsukamoto; Nian-Ling Zhu; Kinji Asahina; Derek A Mann; Jelena Mann
    Hepatology Research, Jul. 2011, Refereed
  • 15th International Symposium on Cells of the Hepatic Sinusoid, 2010
    Laurie D. DeLeve; Hartmut Jaeschke; Vijay K. Kalra; Kinji Asahina; David A. Brenner; Hidekazu Tsukamoto
    Liver International, Jul. 2011, Refereed, URL
  • Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver
    Kinji Asahina; Bin Zhou; William T. Pu; Hidekazu Tsukamoto
    Hepatology, Mar. 2011, Refereed
  • Reply
    Kinji Asahina; Hidekazu Tsukamoto.
    Hepatology, Jul. 2009, Not refereed, Invited, URL
  • A novel method of mouse ex utero transplantation of hepatic progenitor cells into the fetal liver
    Mima Shikanai; Kinji Asahina; Sachiko Iseki; Kenichi Teramoto; Tomohiro Nishida; Keiko Shimizu-Saito; Masato Ota; Kazuhiro Eto; Hirobumi Teraoka
    Biochemical and Biophysical Research Communications, Apr. 2009, Refereed
  • Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development
    Kinji Asahina; Shirley Y. Tsai; Peng Li; Mamoru Ishii; Robert E. Maxson; Henry M. Sucov; Hidekazu Tsukamoto
    Hepatology, Mar. 2009, Refereed
  • Effect of Poly(N-vinyl-pyrrolidone)-block-poly(d,l-lactide) as Coating Agent on the Opsonization, Phagocytosis, and Pharmacokinetics of Biodegradable Nanoparticles
    Geneviève Gaucher; Kinji Asahina; Jiaohong Wang; Jean-Christophe Leroux
    Biomacromolecules, 09 Feb. 2009, Refereed, URL
  • Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog
    Keigo Machida; Hidekazu Tsukamoto; Hasmik Mkrtchyan; Lewei Duan; Alla Dynnyk; Helene Minyi Liu; Kinji Asahina; Sugantha Govindarajan; Ratna Ray; Jing-hsiung James Ou; Ekihiro Seki; Raymond Deshaies; Kensuke Miyake; Michael M.-C. Lai
    Proceedings of the National Academy of Sciences of the United States of America, 03 Feb. 2009, Refereed
  • Vascular endothelial growth factor promotes proliferation and function of hepatocyte-like cells in embryoid bodies formed from mouse embryonic stem cells
    Hiroaki Fujimori; Kinji Asahina; Keiko Shimizu-Saito; Reiko Ikeda; Yujiro Tanaka; Kenichi Teramoto; Ikuo Morita; Hirobumi Teraoka
    Journal of Hepatology, Jun. 2008, Refereed, Corresponding
  • Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis
    Jason H. Cheng; Hongyun She; Yuan-Ping Han; Jiaohong Wang; Shigang Xiong; Kinji Asahina; Hidekazu Tsukamoto
    American Journal of Physiology-Gastrointestinal and Liver Physiology, Jan. 2008, Refereed
  • Involvement of CCAAT/enhancer binding protein-ß (C/EBPß) in epigenetic regulation of mouse methionine adenosyltransferase 1A gene expression
    Reiko Ikeda; Tomohiro Nishida; Fumiaki Watanabe; Keiko Shimizu-Saito; Kinji Asahina; Saburo Horikawa; Hirobumi Teraoka
    International Journal of Biochemistry & Cell Biology, Jan. 2008, Refereed
  • Hepatic Progenitor Cells in the Mouse Extrahepatic Bile Duct after a Bile Duct Ligation
    Takumi Irie; Kinji Asahina; Keiko Shimizu-Saito; Kenichi Teramoto; Shigeki Arii; Hirobumi Teraoka
    Stem Cells and Development, Dec. 2007, Refereed, Corresponding, URL
  • Developmental Pluripotency-associated 4 (DPPA4) Localized in Active Chromatin Inhibits Mouse Embryonic Stem Cell Differentiation into a Primitive Ectoderm Lineage
    Hisaharu Masaki; Tomohiro Nishida; Shigetaka Kitajima; Kinji Asahina; Hirobumi Teraoka
    Journal of Biological Chemistry, Nov. 2007, Refereed, Corresponding
  • Twist Relates to Tubular Epithelial-Mesenchymal Transition and Interstitial Fibrogenesis in the Obstructed Kidney
    Yujiro Kida; Kinji Asahina; Hirobumi Teraoka; Inna Gitelman; Tetsuji Sato
    Journal of Histochemistry & Cytochemistry, Jul. 2007, Refereed, URL
  • Identification of vitamin A-free cells in a stellate cell-enriched fraction of normal rat liver as myofibroblasts
    Tomohiro Ogawa; Chise Tateno; Kinji Asahina; Hideki Fujii; Norifumi Kawada; Masanobu Obara; Katsutoshi Yoshizato
    Histochemistry and Cell Biology, 18 Jan. 2007, Refereed
  • Characterization of vitamin A-storing cells in mouse fibrous kidneys using Cygb/STAP as a marker of activated stellate cells
    Yujiro Kida; Kinji Asahina; Kouji Inoue; Norifumi Kawada; Katsutoshi Yoshizato; Kenjiro Wake; Tetsuji Sato
    Archives of Histology and Cytology, 2007, Refereed, URL
  • Human Cord Blood Cells Transplanted Into Chronically Damaged Liver Exhibit Similar Characteristics to Functional Hepatocytes
    Sei Kakinuma; Kinji Asahina; Kentaro Okamura; Kenichi Teramoto; Chise Tateno; Katsutoshi Yoshizato; Yujiro Tanaka; Takehiko Yasumizu; Naoya Sakamoto; Mamoru Watanabe; Hirobumi Teraoka
    Transplantation Proceedings, Jan. 2007, Refereed
  • Embryonic Stem Cells: Hepatic Differentiation and Regenerative Medicine for the Treatment of Liver Disease
    Kinji Asahina; Kenichi Teramoto; Hirobumi Teraoka
    Current Stem Cell Research & Therapy, 01 May 2006, Refereed, Invited, URL
  • Multiplicative mononuclear small hepatocytes in adult rat liver: Their isolation as a homogeneous population and localization to periportal zone
    Kinji Asahina; Miho Shiokawa; Takuro Ueki; Chihiro Yamasaki; Akio Aratani; Chise Tateno; Katsutoshi Yoshizato
    Biochemical and Biophysical Research Communications, Apr. 2006, Refereed, Lead
  • Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver
    Kentaro Okamura; Kinji Asahina; Hiroaki Fujimori; Rie Ozeki; Keiko Shimizu-Saito; Yujiro Tanaka; Kenichi Teramoto; Shigeki Arii; Kozo Takase; Miho Kataoka; Yoshinori Soeno; Chise Tateno; Katsutoshi Yoshizato; Hirobumi Teraoka
    Histochemistry and Cell Biology, Mar. 2006, Refereed, Corresponding
  • Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks
    Ryo Sakasai; Keitaro Shinohe; Yosuke Ichijima; Naoyuki Okita; Atsushi Shibata; Kinji Asahina; Hirobumi Teraoka
    Genes to Cells, Mar. 2006, Refereed
  • Phosphorylation of histone H2AX at M phase in human cells without DNA damage response
    Yosuke Ichijima; Ryo Sakasai; Naoyuki Okita; Kinji Asahina; Shuki Mizutani; Hirobumi Teraoka
    Biochemical and Biophysical Research Communications, Oct. 2005, Refereed
  • Efficient in vivo xenogeneic retroviral vector-mediated gene transduction into human hepatocytes
    Kentaro Emoto; Chise Tateno; Hiroshi Hino; Hironobu Amano; Yasuhiro Imaoka; Kinji Asahina; Toshimasa Asahara; Katsutoshi Yoshizato
    Human Gene Therapy, Oct. 2005, Refereed
  • Hepatocyte differentiation from embryonic stem cells and umbilical cord blood cells
    Kenichi Teramoto; Kinji Asahina; Yuji Kumashiro; Sei Kakinuma; Ryoko Chinzei; Keiko Shimizu-Saito; Yujiro Tanaka; Hirobumi Teraoka; Shigeki Arii
    Journal of Hepato-Biliary-Pancreatic Surgery, 27 Jun. 2005, Refereed, URL
  • Enrichment of Hepatocytes Differentiated from Mouse Embryonic Stem Cells as a Transplantable Source
    Yuji Kumashiro; Kinji Asahina; Rie Ozeki; Keiko Shimizu-Saito; Yujiro Tanaka; Yujiro Kida; Kouji Inoue; Michinari Kaneko; Tetsuji Sato; Kenichi Teramoto; Shigeki Arii; Hirobumi Teraoka
    Transplantation, 15 Mar. 2005, Refereed, Corresponding, URL
  • Teratoma formation and hepatocyte differentiation in mouse liver transplanted with mouse embryonic stem cell–derived embryoid bodies
    Kenichi Teramoto; Yuzuru Hara; Yuji Kumashiro; Ryoko Chinzei; Yujiro Tanaka; Keiko Shimizu-Saito; Kinji Asahina; Hirobumi Teraoka; Shigeki Arii
    Transplantation Proceedings, Jan. 2005, Refereed
  • Isolation of hepatocyte-like cells from mouse embryoid body cells
    Yuji Kumashiro; Kenichi Teramoto; Keiko Shimizu-Saito; Kinji Asahina; Hirobumi Teraoka; Shigeki Arii
    Transplantation Proceedings, Jan. 2005, Refereed, Corresponding
  • Expression of the liver-specific gene Cyp7a1 reveals hepatic differentiation in embryoid bodies derived from mouse embryonic stem cells
    Kinji Asahina; Hiroaki Fujimori; Keiko Shimizu-Saito; Yuji Kumashiro; Kentaro Okamura; Yujiro Tanaka; Kenichi Teramoto; Shigeki Arii; Hirobumi Teraoka
    Genes to Cells, 25 Nov. 2004, Refereed
  • Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs
    Chise Tateno; Yasumi Yoshizane; Naomi Saito; Miho Kataoka; Rie Utoh; Chihiro Yamasaki; Asato Tachibana; Yoshinori Soeno; Kinji Asahina; Hiroshi Hino; Toshimasa Asahara; Tsuyoshi Yokoi; Toshinori Furukawa; Katsutoshi Yoshizato
    American Journal of Pathology, Sep. 2004, Refereed
  • Characterization of human stellate cell activation-associated protein and its expression in human liver
    Kinji Asahina; Norifumi Kawada; Dan Bach Kristensen; Kazuki Nakatani; Shuichi Seki; Miho Shiokawa; Chise Tateno; Masanobu Obara; Katsutoshi Yoshizato
    Biochimica et Biophysica Acta- Gene Structure and Expression, Sep. 2002, Refereed, Lead
  • Pleiotrophin/Heparin-Binding Growth-Associated Molecule as a Mitogen of Rat Hepatocytes and Its Role in Regeneration and Development of Liver
    Kinji Asahina; Hajime Sato; Chihiro Yamasaki; Miho Kataoka; Miho Shiokawa; Shigeru Katayama; Chise Tateno; Katsutoshi Yoshizato
    American Journal of Pathology, Jun. 2002, Refereed, Lead
  • Characterization of a Stellate Cell Activation-associated Protein (STAP) with Peroxidase Activity Found in Rat Hepatic Stellate Cells
    Norifumi Kawada; Dan Bach Kristensen; Kinji Asahina; Kazuki Nakatani; Yukiko Minamiyama; Shuichi Seki; Katsutoshi Yoshizato
    Journal of Biological Chemistry, Jan. 2001, Refereed, URL
  • Developmentally and regionally regulated participation of epidermal cells in the formation of collagen lamella of anuran tadpole skin
    Rie Utoh; Kinji Asahina; Kenichi Suzuki; Kaori Kotani; Masanobu Obara; Katsutoshi Yoshizato
    Development, Growth and Differentiation, Dec. 2000, Refereed
  • Kdap, a novel gene associated with the stratification of the epithelium
    Souichi Oomizu; Florent Sahuc; Kinji Asahina; Mutsumi Inamatsu; Takashi Matsuzaki; Masakazu Sasaki; Masanobu Obara; Katsutoshi Yoshizato
    Gene, Oct. 2000, Refereed
  • Expression of genes of type I and type II collagen in the formation and development of the blastema of regenerating newt limb
    Kinji Asahina; Masanobu Obara; Katsutoshi Yoshizato
    Developmental Dynamics, Sep. 1999, Refereed, Lead, URL
  • Cell-type specific and thyroid hormone-dependent expression of genes of α1(I) and α2(I) collagen in intestine during amphibian metamorphosis
    Kinji Asahina; Rie Utoh; Masanobu Obara; Katsutoshi Yoshizato
    Matrix Biology, Feb. 1999, Refereed, Lead
  • Cloning and characterization of the full length cDNA encoding α2 type I collagen of bullfrog Rana catesbeiana
    Kinji Asahina; Ken Oofusa; Masanobu Obara; Katsutoshi Yoshizato
    Gene, Jul. 1997, Refereed, Lead
■ MISC
  • Alcohol drinking promotes pancreatic cancer development
    Soi Jeong S; Kinji Asahina
    Hepato-biliary pancreas, Apr. 2023
  • Lineage of mesothelial cells in development and wound healing
    Kinji Asahina
    Japanese Society for the Research of Hepatic Cells, Dec. 2022
  • The developmental origin of hepatic stellate cells
    Kinji Asahina
    Hepato-biliary pancreas, Apr. 2021
  • Origins of fibrillar collagen-producing cells in organ development and fibrosis
    Kinji Asahina
    J Clin Exp Med, Dec. 2020
    https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2020&ichushi_jid=J00060&link_issn=&doc_id=20201207020003&doc_link_id=40022427082&url=http%3A%2F%2Fci.nii.ac.jp%2Fnaid%2F40022427082&type=CiNii&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00003_1.gif
  • Cell types involved in liver fibrosis
    Kinji Asahina
    Hepatobiliary and Pancreatic, Aug. 2012
  • Sinusoid
    Kinji Asahina
    Biochemistry, 2012
  • Hepatic stellate cells
    Kinji Asahina
    Japanese Society for the Research of Hepatic Cells, Jul. 2009
  • Progenitor cells present in the extrahepatic bile duct
    Takumi Irie; Kinji Asahina; Keiko Saito; Kenichi Teramoto; Shigeki Arii; Hirobumi Teraoka
    Organ Biology, Dec. 2007
  • Hepatic differentiation of monkey ES cells
    Kentaro Okamura; Kinji Asahina; Keiko Saito; Kozo Takase; Hirobumi Teraoka
    Regenerative Medicine, Feb. 2006
    https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2006&ichushi_jid=J03810&link_issn=&doc_id=20060202290004&doc_link_id=40007164784&url=http%3A%2F%2Fci.nii.ac.jp%2Fnaid%2F40007164784&type=CiNii&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00003_1.gif
  • Hepatic differentiation of ES cells
    Kenichi Teramoto; Yuji Kumashiro; Takkumi Irie; Shigeki Arii; Kinji Asahina; Keiko Saito; Hirobumi Teraoka
    Cytoprotection, 2006, Not refereed
  • Separation of small hepatocytes
    Kinji Asahina; Chise Tateno; Katsutoshi Yoshizato
    Cell, Dec. 2005
  • Tissue Stem Cells
    Kinji Asahina; Chise Tateno; Katsutoshi Yoshizato
    Tissue Engineering, Feb. 2005
  • 58th Japanese Society for Cell Biology
    Kinji Asahina
    Cell Engineering, 2005
  • Use of cord blood cells for regenerative medicine
    Kinji Asahina; Keiko Saito; Hirobumi Teraoka
    Cell, Feb. 2004
  • Transplantation of hepatocytes induced from ES cells or cord blood cells
    Hirobumi Teraoka; Kinji Asahina; Keiko Saito
    Pediatric Surgery, 2004
  • Tissue stem cells
    Kinji Asahina
    Medicina, 2002
  • ES cells and tissue stem cells for regenerative medicine
    Kinji Asahina; Chise Tateno; Katsutoshi Yoshizato
    G. I. Research, 2001
  • Expression of Kdap in skin development
    Sahuc Florent; 大水 総一; 稲松 睦; 松崎 貴; 朝比奈 欣治; 佐々木 正和; 小原 政信; 吉里 勝利
    Japanese Society for Investigative Dermatology, Jun. 1999, Not refereed, Not invited
  • Collagens in organogenesis
    Masanobu Obara; Kinji Asahina; Katsutoshi Yoshizato
    Biochemistry, 1998, Not refereed, Invited
■ Books and other publications
  • Stem Cells and Cancer
    Kinji Asahina; Kenichi Teramoto; Shigeki Arii; Hirobumi Teraoka, Joint work, Transplantation of embryonic stem cell-derived hepatocytes and risk of teratoma formation
    Nova Science Publishers, 2007
  • Regenerative Medicine
    Kinji Asahina; Chise Tateno; Katsutoshi Yoshizato
    Yodosya, Apr. 2004
    4897068800
  • Metamorphosis
    Ienichi Suzuki; Kinji Asahina; Katsutoshi Yoshizato, Joint work
    Tokyo Kagaku Dojin, 2001
  • Proteome analysis
    Akira Yamagata; Kinji Asahina; Katsutoshi Yoshizato, Joint work, Stem cells and regenerative medicine
    Yodosha, 2001
■ Lectures, oral presentations, etc.
  • Role of hepatic stellate cells and mesothelial cells in liver fibrosis
    Kinji Asahina
    SUMS grand round, 18 Nov. 2025
  • Crosstalk of mesothelial cells and peritoneal macrophages in organ fibrosis
    Kinji Asahina
    30th Japan Endotoxin and Innate Immunity Society, 14 Nov. 2025, Invited
  • Crosstalk of liver mesothelial cells and peritoneal macrophages
    Kinji Asahina
    39th Hepatic Sinusoidal Research Japan, 26 Jul. 2025
  • Role of mesothelial cells and peritoneal macrophages in liver fibrosis
    Kinji Asahina
    International Seminars in Physiology Series, University of Thessaly, Greece, 07 May 2025, Invited
  • Live imaging of mesothelial-mesenchymal transition in vivo
    Kinji Asahina
    38th Japanese Society for the Research of Hepatic Cells, 14 Dec. 2024
  • Structure of liver Glisson's capsule in mammalian species
    Kinji Asahina; Hiroki Uchida; Naoyuki Aihara; Junichi Kamiie
    31st Japanese Society for the Research of Hepatic Cells, 26 Jul. 2024
  • Unexpected roles of mesothelial cells and peritoneal macrophages in liver fibrosis
    Kinji Asahina
    Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, 11 Mar. 2024
  • Recruitment of peritoneal macrophages to fibrotic liver surface
    Kinji Asahina
    30th Japanese Society for the Research of Hepatic Cells, 25 Aug. 2023, Not invited
  • Liver fibrosis
    Kinji Asahina
    SUMS grand round, 27 Feb. 2023
  • Single-cell RNA sequencing analysis in murine biliary atresia model reveals subpopulation of biliary epithelial cells with proinflammatory and fibrogenic traits
    Short C; Zhong A, Xu J; Asahina K; Wang KS
    The American College of Surgeon,, 17 Oct. 2022
  • Prom1+ biliary progenitor cells display abnormal cellular polarity and ciliopathy in murine biliary atresia
    Zhong A; Short C; Xu J; Asahina K; Wang KS
    The American College of Surgeon, 17 Oct. 2022
  • Single cell RNA sequencing analysis in murine biliary atresia model reveals subpopulation of biliary epithelial cells with pro-inflammatory and fibrogenic traits
    Short C; Zhong A; Xu J; Asahina K; Wang KS
    American Academy of Pediatrics, 08 Oct. 2022
  • Disruption of Prom1-mediated cell polarity and ciliary structure in biliary progenitor cells decreases biliary regeneration in murine biliary atresia
    Zhong A; Short C; Xu J; Asahina K; Wang KS
    American Academy of Pediatrics, 08 Oct. 2022
  • Cell lineages in liver development and fibrosis
    Kinji Asahina
    29th Japanese Society for the Research of Hepatic Cells, 26 Aug. 2022, Not invited
  • Role of TAZ in mesothelial-mesenchymal transition
    Kinji Asahina
    29th Japanese Society for the Research of Hepatic Cells, 25 Aug. 2022
  • Interaction between the liver and peritoneal cavity
    Kinji Asahina
    SUMS pioneer seminar, 27 Jun. 2022
  • Role of lysophosphatidic acids in steatosis
    Kinji Asahina
    68th Japanese Society of Biochemistry, 28 May 2022
  • Role of mesothelial cells in liver capsular fibrosis
    Kinji Asahina
    127th Japanese Association of Anatomists Annual Meeting, 27 Mar. 2022
  • Inhibition of Fn14 reduces fibrosis and ductular reactions in murine biliary atresia model
    Short C.; Zhong A.; Xu J.; Yeo T.; Malkoff N.; Asahina K.; Wang K.
    17th Annual Academic Surgical Congress, 01 Feb. 2022
  • Emergence of highly fibrogenic LRAT+ FBLN2+ hepatic stellate cell subpopulation in alcoholic hepatitis
    Fujiwara R.; Balog S.; Pan SQ; Asahina K.; Tsukamoto H.
    American Association for the Study of Liver Disease, 12 Nov. 2021
  • Prominin-1-expressing hepatic progenitor cells promote liver fibrogenesis via Mmp7-mediated signaling pathways during cholestatic liver injury
    Short C.; Zhong A.; Xu J.; Asahina K.; Wang KS
    American College of Surgeons Clinical Congress 2021, 23 Oct. 2021
  • PROM1+ biliary progenitor cells reside in peribiliary glands and proliferate into cholangiocytes in response to cholestatic injury in murine biliary atresia models
    Zhong A.; Short C.; Fernandez E.; Xu J.; Asahina K.; Wang KS
    American College of Surgeons Clinical Congress 2021, 23 Oct. 2021
  • The cholesterol-binding translocator protein (18 kDa) regulates hepatic steatosis and bile acid synthesis in non-alcoholic fatty liver disease
    Li Y.; Chen L.; Li L.; Sottas C.; Petrillo SK; Lazaris A.; Metrakos P.; Wu H.; Ishida Y.; Takeshi Saito T.; Golden-Mason L.; Rosen HR; Wolff J.; Silvescu CI; Garza S.; Cheung G.; Huang T.; Fan J.; Culty M.; Stiles B.; Asahina K.; Papadopoulos V.
    Keystone Symposia, 22 Mar. 2021
  • Fn14 is associated with fibrogenesis in murine biliary atresia model
    Short CA; Xu J.; Mahdi E.; Glazier AT; Asahina K.; Wang KS
    American College of Surgeons Clinical Congress 2020, 04 Oct. 2020
  • Capsular fibrosis from Glisson’s capsule beneath the liver surface.
    Kinji Asahina
    Biology Online Seminar Series 2020, 05 May 2020
  • Inhibition of stearoyl-CoA desaturase suppresses growth of pancreatic tumors in vitro and in vivo.
    Skrypek K; Balog S; Asahina K
    Experimental Biology 2020, ASBMB annual meeting., 05 Apr. 2020
  • Promotion of pancreatic cancer by alcohol intake and suppression of their growth by targeting lipid metabolism
    Kinji Asahina
    22nd Annual Pathology Conference of the University of Southern California, 22 Feb. 2019
  • Ablation of Prominin-1 hepatic cells after bile duct ligation mitigates pro-fibrogenic expression
    Fenlon MR; Malkoff N.; Xu J.; Mahdi E.; Glazier A.; Lee C.; Oweis R.; Asahina K.; Wang KS
    14th Annual Academic Surgical Congress, 05 Feb. 2019
  • Role of lysophosphatidic acid in liver steatosis and fibrosis
    Kinji Asahina
    Tokai University-USC Workshop on Steatohepatitis, Liver Fibrosis and HCC, 07 Nov. 2018
  • Prominin-1 hepatic progenitor cell differentiation via lineage tracing in biliary fibrosis
    Fenlon MR; Xu J.; Lee C.; Oweis, R.; Asahina K.; Wang KS
    Society of Asian Academic Surgeons 3rd Annual Meeting, 27 Sep. 2018
  • Promotion of pancreatic cancer development by alcohol and Western diet feeding.
    Asahina K
    13th International Symposium on ALPD and Cirrhosis., 10 Sep. 2018
  • Exploring the new role of mesothelial cells in liver development and disease.
    Asahina K
    1st TMDU-UCSD-USC Joint Symposium., 05 Sep. 2018
  • Role of lysophosphatidic acids in liver injury.
    Asahina K
    27th meeting of Suntory Alcohol and Health Research., 06 Jul. 2018
  • Differential response to Prominin-1 hepatic progenitor cellular ablation in adult mice compared to newborn
    Fenlon MR; Xu J.; Asahina K.; Wang KS
    American Pediatric Surgical Association 2018 Annual Meeting, 03 Mar. 2018
  • Identification and genesis of tumor-initiating stem cell-like cells in alcohol-promoted PDAC
    Kinji Asahina
    Pilot Funding Programs at the Keck School, 07 Feb. 2018
  • PROMININ-1 hepatic progenitor cell ablation increases hepatic fibrosis in bile duct ligation
    Fenlon MR; Xu J.; Zagory J.; Asahina K.; Wang K.
    13th Annual Academic Surgical Congress, 30 Jan. 2018
  • Role of lysophosphatidic acids in alcoholic liver steatosis.
    Asahina K
    26th meeting of Suntory Alcohol and Health Research., 01 Sep. 2017
  • New PDAC project development
    Kinji Asahina
    The Southern California Research Center for ALPD & Cirrhosis, Center project retreat, 25 Aug. 2017
  • Effects of alcohol on acinar to ductal metaplasia in pancreatic cancer development
    Wan E.; Asahina K.
    The 2017 Progress Report Meeting for the 17th Lee Summer Research Fellows, 11 Aug. 2017
  • Suppression of liver steatosis and fibrosis by targeting lysophosphatidic acid signaling
    Lua I.; Asahina K.
    20th Annual Pathology Conference of the USC, 03 Mar. 2017
  • Identification of Integrin a8 as a specific surface marker for liver mesenchymal cells that negatively regulate maturation of liver progenitor cells in development
    Ogawa T.; Asahina K.
    20th Annual Pathology Conference of the USC, 03 Mar. 2017
  • Fate of CD133+ progenitors in AH
    Raymond Wu; Kinji Asahina
    Southern California Research Center for ALPD & Cirrhosis, 02 Dec. 2016
  • Tumor-initiating stem cell-like cells in alcohol-promoted PDAC
    Kinji Asahina
    Southern California Research Center for ALPD & Cirrhosis, 02 Dec. 2016
  • Mesothelial cells: Mesenchymal progenitor cells in development, injury and regeneration
    Ingrid Lua; Kinji Asahina
    Emerging innovations in developmental and stem cell biology, 08 Apr. 2016
  • Determination of the source of myofibroblasts in liver fibrosis
    Lua I.; Asahina K.
    19th Annual Pathology Conference of the University of Southern California, 19 Feb. 2016
  • Lipid mediators in liver fibrosis
    Kinji Asahina
    Southern California Research Center for ALPD & Cirrhosis, 04 Dec. 2015
  • Myofibroblastic conversion of portal fibroblasts and mesothelial cells isolated from adult mouse liver.
    Lua I; Asahina K
    American Association for the Study of Liver Diseases, The liver meeting 2015., 16 Nov. 2015
  • TGF-b induces the conversion of mesothelial cells to myofibroblasts during liver fibrosis.
    Li Y; Lua I; Asahina K
    18th International society for hepatic sinusoidal research meeting., 12 Nov. 2015
  • Induction of capsular fibrosis by chlorhexidine gluconate in mouse liver.
    Lua I, Li Y; Asahina K
    18th International society for hepatic sinusoidal research meeting., 11 Nov. 2015
  • Roles of Glisson’s capsule in capsular fibrosis in human and mouse livers
    Lua I, Li Y.; Asahina K.
    10th International symposium on alcoholic liver and pancreatic diseases and cirrhosis, 30 Sep. 2015
  • Lysophosphatidic acid and liver fibrosis.
    Lua I; Razipour S; Asahina K
    FASEB Science Research Conferences., 24 Aug. 2015
  • The conversion of mesothelial cells to myofibroblasts regulated by TGF- and lysophosphatidic acids
    Razipour S.; Asahina K.
    Lee Summer Fellowship Program, Southern California Research Center for ALPD and Cirrhosis, 14 Aug. 2015
  • Role of LPA and Hippo signaling in liver fibrosis
    Lua I.; Asahina K.
    18th Annual Pathology Conference of the University of Southern California, 20 Feb. 2015
  • Role of mesothelial cells in development, injury, and regeneration.
    Asahina K
    University of California, San Francisco, 17 Dec. 2014
  • Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury.
    Lua I; Asahina K
    FASEB Summer Research Conferences., 08 Jul. 2014
  • Peritoneal mesothelial cells give rise to myofibroblasts via mesothelial-mesenchymal transition in peritoneal fibrosis.
    Lua I; Asahina K
    Experimental Biology 2014., 26 Apr. 2014
  • No evidence for transition of mesenchymal cells to epithelial stem cells in mouse liver injury
    Lua I.; Asahina K.
    USC 6th Annual Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research Retreat,, 20 Oct. 2013
  • Mesothelial-mesenchymal transition in liver development and fibrosis.
    Asahina K
    17th International Symposium on Cells of the Hepatic Sinusoid., 23 Sep. 2013
  • Recent progress in liver cirrhosis
    Lua I.; Asahina K.
    North America Taiwanese Professors’ Association Southern California Chapter 2013 Spring Conference, 30 Mar. 2013
  • Mesothelial cells: mesenchymal progenitor cells in liver development and fibrosis.
    Asahina K
    University of Arkansas for Medical Sciences., 27 Feb. 2013
  • Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury
    Li Y.; Asahina K.
    16th Annual Pathology Conference of the University of Southern California, 01 Feb. 2013
  • Mesothelial reaction in alcoholic hepatitis
    Kinji Asahina
    U01-P50 Alcohol Hepatitis Collaborative Meeting, 25 Jan. 2013
  • Mesothelial cells: mesenchymal progenitor cells in liver development and fibrogenesis
    Kinji Asahina
    Department of Pathology Special Seminar, USC, 06 Dec. 2012
  • The role of b-catenin in stellate cell activation and proliferation of tumor initiating cells induced by PTEN loss
    Medina VG; He L.; Kassa AD; Gubbins JD; Kahn M.; Asahina K.; Stiles BL
    63th Annual Meeting of the American Association for the Study of Liver Diseases, 02 Nov. 2012
  • DLK1 in alcoholic liver fibrosis, regeneration, and cancer
    Tsukamoto H.; Zhu NL; Asahina K.; Machida K.
    2012 ISBRA World Congress, 09 Sep. 2012
  • Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver fibrosis.
    Li Y; Wang J; Asahina K
    7th International Symposium on ALPD and Cirrhosis., 07 Sep. 2012
  • Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver fibrosis.
    Asahina K; Li; Tsukamoto H
    FASEB Summer Research Conferences., 20 Jul. 2012
  • Contribution of the liver mesothelium to liver fibrogenesis
    Kinji Asahina
    USC Research Center for Liver Disease, 09 Mar. 2012
  • Transdifferentiation of mesothelial cells to myofibroblasts via epithelial-mesenchymal transition during liver fibrogenesis.
    Asahina K; Tsukamoto H
    62nd Annual Meeting of the American Association for the Study of Liver Diseases., 07 Nov. 2011
  • Cell lineage analysis of hepatic stellate cells and different liver mesenchymal cells in mouse embryos.
    Asahina K; Tsukamoto H
    6th International Symposium on ALPD and Cirrhosis., 21 Oct. 2011
  • Hepatic stellate cell progenitor in embryo and adult.
    Asahina K; Tsukamoto H
    6th International Symposium on ALPD and Cirrhosis., 20 Oct. 2011
  • Contribution of the liver mesothelium to alcohol-induced liver fibrogenesis
    Kinji Asahina
    Southern California Research Center Renewal Retreat, 15 Jul. 2011
  • Contribution of the liver mesothelium to liver fibrogenesis
    Kinji Assahina
    USC Research Center for Liver Disease, 11 Mar. 2011
  • Hepatic stellate cell lineage
    Kinji Asahina
    14th Annual Pathology Conference, 21 Jan. 2011
  • Hepatic stellate cell precursors in developing and fibrotic livers
    Kinji Asahina
    Southern California Research Center for ALPD and Cirrhosis, 03 Dec. 2010
  • Septum transversum-derived mesothelium gives rise to hepatic stellate cells and portal fibroblasts in mouse embryonic liver.
    Asahina K; Tsukamoto H
    61th Annual Meeting of the American Association for the Study of Liver Diseases., 02 Nov. 2010
  • Mesothelial/submesothelial cells give rise to hepatic stellate cells in mouse liver development.
    Asahina K; Tsukamoto H
    15th International Symposium on Cells of the Hepatic Sinusoid., 30 Aug. 2010
  • Septum transversum mesenchyme-derived mesothelium gives rise to hepatic stellate cells during mouse liver development.
    Asahina K; Tsukamoto H
    FASEB Summer Research Conferences., 17 Aug. 2010
  • Hepatic stellate cell precursors in developing and fibrotic livers
    Kinji Asahina
    Joint symposium: Southern California Research Center for ALPD and Cirrhosis and UCSD Diabetes and Endocrinology Research Center, 04 Dec. 2009
  • Necdin cross-talks with canonical Wnt and Shh pathways and contributes to anti-adipogenic trans-differentiation of hepatic stellate cells
    Zhu NL; Wang J.; Lai K.; Asahina K.; Tsukamoto H.
    The 60th Annual Meeting of the American Association for the Study of Liver Diseases, 02 Nov. 2009
  • Developmental origin of hepatic stellate cells and their possible precursors.
    Asahina K; Xie B; Tsukamoto H
    60th Annual Meeting of the American Association for the Study of Liver Diseases, 02 Nov. 2009
  • Hepatic stellate cell precursors in developing and regenerating livers
    Kinji Asahina
    Southern California Research Center for ALPD & Cirrhosis, 05 Dec. 2008
  • In vitro and in vivo evaluation of poly(N-vinyl-pyrrolidone)-coated poly(D,L-lactide) nanoparticles
    Gaucher G.; Asahina K.; Wang J.; Leroux JC
    NanoDDS’08, 18 Oct. 2008
  • Canonical Wnt signaling and hepatic stellate cells. 14th International Symposium on cells of the hepatic sinusoid
    Tsukamoto H.; Cheng JH; She H.; Han YP; Asahina K.
    14th International Symposium on cells of the hepatic sinusoid, 31 Aug. 2008
  • 肝関連遺伝子発現におけるエピジェネティクス制御
    池田玲子; 西田知弘; 藤森浩彰; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第2回日本エピジェネティクス研究会年会, 09 May 2008
  • 肝細胞-内皮細胞相互作用を利用した、ES細胞由来胚様体内肝細胞の増殖・機能促進
    藤森浩彰; 朝比奈欣治; 森田育男; 寺岡弘文
    第7回再生医療学会総会, 14 Mar. 2008
  • クロマチン結合因子DPPA4はES細胞において原始外胚葉への分化を阻害する
    正木久晴; 西田知弘; 北島繁孝; 朝比奈欣治; 寺岡弘文
    第7回再生医療学会総会, 14 Mar. 2008
  • Ex utero 法を用いたマウス胎仔肝臓への肝前駆細胞の移植
    鹿内弥磨; 朝比奈欣治; 井関祥子; 太田正人; 西田知弘; 藤剛志; 齊藤佳子; 寺岡弘文
    第14回肝細胞研究会, 23 Jun. 2007
  • マウス肝外胆管に存在する肝前駆細胞の解明
    入江工; 朝比奈欣治; 齊藤桂子; 寺本研一; 有井滋樹; 寺岡弘文
    第107回外科学会定期学術集会, 12 Apr. 2007
  • 肝外胆管に存在する肝前駆細胞の解明
    入江工; 朝比奈欣治; 齊藤桂子; 寺本研一; 有井滋樹; 寺岡弘文
    第6回再生医療学会総会, 14 Mar. 2007
  • Ex utero法を用いた胎仔肝臓への移植モデルの開発とES細胞由来肝芽様細胞の移植
    鹿内弥磨; 朝比奈欣治; 齊藤剛志; 齊藤桂子; 寺岡弘文; 井関祥子; 太田正人; 江藤一洋
    第6回再生医療学会総会, 14 Mar. 2007
  • VEGFは胚様体中での肝細胞—血管内皮細胞相互作用を通じてES細胞からの肝細胞分化誘導を促進する
    藤森浩彰; 朝比奈欣治; 齊藤佳子; 森田育男; 寺岡弘文
    第14回日本血管生物医学会, 13 Dec. 2006
  • マウスES細胞における未分化関連因子Dppa4の機能解析
    正木久晴; 朝比奈欣治; 市島洋介; 西田知弘; 寺岡弘文
    分子生物学会2006フォーラム, 08 Dec. 2006
  • ラット正常肝から分離した筋線維芽細胞特性の解析
    小川智弘; 立野知世; 朝比奈欣治; 藤井英樹; 河田則文; 小原政信; 吉里勝利
    第20回肝類洞壁細胞研究会, 02 Dec. 2006
  • 肝外胆管における幹細胞システムの解析
    入江工; 寺本研一; 有井滋樹; 朝比奈欣治; 斉藤佳子; 寺岡弘文
    第33回日本臓器保存生物学会総会, 24 Nov. 2006
  • Hepatic progenitor cells in extrahepatic bile duct of adult mice.
    Asahina K; Irie T; Teraoka H
    19th Naito Conference, 15 Nov. 2006
  • Twist relates to epithelial-mesenchymal transition in tubular epithelial cells of fibrous kidney
    Kida Y.; Asahina K.; Teraoka H.; Gitelman I.; Sato T.
    The American Society of Nephrology’s 39th Annual Renal Week Meeting, 14 Nov. 2006
  • Analysis of extrahepatic-stellate cells using cytoglobin/STAP in experimental fibrosis
    Kida Y.; Asahina K.; Inoue K.; Kawada N.; Yoshizato K.; Wake K.; Sato T.
    13th International Symposium on Cells of the Hepatic Sinusoid, 03 Sep. 2006
  • VEGF promotes hepatocyte differentiation in embryoid bodies formed from mouse embryonic stem cells.
    Asahina K; Fujimori H; Shimizu-Saito K; Teraoka H
    FASEB Summer Research Conferences., 23 Jul. 2006
  • Hepatocyte differentiation and teratoma formation after transplantation of embryoid-body cells derived from murine and primate embryonic stem cells into injured mouse liver
    Teramoto K.; Asahina K.; Okamura K.; Kumashiro Y.; Irie T.; Shimizu-Saito K.; Teraoka H.; Arii S.
    World Transplant Congress, 22 Jul. 2006
  • VEGFはES細胞由来胚様体における肝細胞分化を促進する
    藤森浩彰; 朝比奈欣治; 齊藤佳子; 寺岡弘文
    第13回肝細胞研究会, 30 Jun. 2006
  • Search for a kinase responsible for phosphorylation of H2AX (Ser139) in a DNA damage-independent and cell cycle-dependent manner
    Ichijima Y.; Sakasai R.; Asahina K.; Teraoka H.
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, 23 Jun. 2006
  • Cell cycle checkpoint in monkey embryonic stem cells treated with neocarzinostatin
    Shinohe K.; Okamura K.; Ichijima Y.; Sakasai R.; Shimizu-Saito K.; Asahina K.; Teraoka H.
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, 23 Jun. 2006
  • DNA-PK and ATR independently participate in RPA2 focus formation and hyperphosphorylation in response to replication-mediated DNA double-strand breaks
    Sakasai R.; Ichijima Y.; Shinohe K.; Asahina K.; Teraoka H.
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, 22 Jun. 2006
  • Differentiation of mouse embryonic stem cells overexpressing nodal-related genes
    Nishida T.; Asahina K.; Masaki H.; Saito T.; Shikanai M.; Shimizu-Saito K.; Teraoka H.
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, 22 Jun. 2006
  • Liver myofibroblasts as a new mesenchymal cell population that might play a role in hepatic remodeling
    Ogawa T.; Tateno C.; Asahina K.; Fujii H.; Kawada N.; Obara M.; Yoshizato K.
    日本発生生物学会第39回大会, 02 Jun. 2006
  • 霊長類ES細胞からの肝細胞分化誘導と肝傷害マウスへの移植
    朝比奈欣治; 岡村健太郎; 齊藤佳子; 寺本研一; 有井滋樹; 田中雄二郎; 高瀬浩造; 立野知世; 吉里勝利; 寺岡弘文
    日本組織培養学会第79回大会, 25 May 2006
  • 非肝細胞系(ES細胞、臍帯血細胞)からの肝細胞分化誘導の試み
    寺本研一; 朝比奈欣治; 寺岡弘文; 有井滋樹
    第111回日本解剖学会総会, 31 Mar. 2006
  • 胆管結紮法による幼若胆管上皮細胞の分離・培養の試み
    入江工; 朝比奈欣治; 齊藤佳子; 寺本研一; 有井滋樹; 寺岡弘文
    第106回日本外科学会定期学術集会, 30 Mar. 2006
  • 胆管結紮法による幼若胆管上皮細胞の分離・培養の試み
    入江工; 朝比奈欣治; 齊藤佳子; 寺本研一; 有井滋樹; 寺岡弘文
    第5回日本再生医療学会総会, 08 Mar. 2006
  • 肝障害マウスに移植したカニクイザルES細胞由来細胞とマウス肝細胞のcell fusionによる肝再生
    岡村健太郎; 藤森浩彰; 田中雄二郎; 高瀬浩造; 片岡美穂; 添野吉徳; 立野知世; 吉里勝利; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第28回日本分子生物学会年会, 09 Dec. 2005
  • マウスES細胞からの肝細胞分化誘導における血管内皮細胞の重要性
    藤森浩彰; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第28回日本分子生物学会年会, 09 Dec. 2005
  • Phosphorylation of histone H2AX at M phase in human cells without DNA damage response
    Ichijima Y.; Sakasai R.; Okita N.; Asahina K.; Mizutani S.; Teraoka H.
    第28回日本分子生物学会年会, 07 Dec. 2005
  • マウス肝発生におけるMAT1A遺伝子発現のエピジェネティクスの検討
    池田玲子; 西田知弘; 酒井綾子; 沖田直之; 逆井良; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第28回日本分子生物学会年会, 07 Dec. 2005
  • DNA複製に伴うDNA二本鎖切断応答におけるRPA2の高リン酸化に対するATR及びDNA-PKの異なる作用点
    逆井良; 四戸啓太郎; 市島洋介; 沖田直之; 朝比奈欣治; 寺岡弘文
    第28回日本分子生物学会年会, 07 Dec. 2005
  • Phosphorylation of histone H2AX at M phase in human cells without DNA damage response
    Ichijima Y.; Sakasai R.; Okita N.; Asahina K.; Teraoka H.
    The 5th International 3R Symposium, 16 Nov. 2005
  • Differential involvement of DNA-PK and ATR in RPA2 hyperphosphorylation in response to replication-mediated DNA double-strand breaks
    Sakasai R.; Shinohe K.; Ichijima Y.; Okita N.; Asahina K.; Teraoka H.
    The 5th International 3R Symposium, 16 Nov. 2005
  • Hepatic differentiation from ES cells and regenerative medicine for the treatment of liver disease
    Asahina K.
    Osaka City Liver Club, 20 Aug. 2005
  • マウス肝臓おけるMAT1A遺伝子のエピジェネティクスの検討
    池田玲子; 西田友弘; 酒井綾子; 沖田直之; 逆井良; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第12回肝細胞研究会, 09 Jul. 2005
  • マウスES細胞からの肝細胞分化における局所的なVEGF発現の効果
    藤森 浩彰; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第12回肝細胞研究会, 08 Jul. 2005
  • 非対称性胚様体形成による新しい組織構築の制御方法
    朝比奈欣治
    文部科学省 科学研究費補助金「特定領域研究」マルチスケール操作によるシステム細胞工学(バイオ操作)第3回公開シンポジウム, 30 Jun. 2005
  • Differentiation of hepatocyte-like cells from monkey ES cells in vitro and cell fusion between monkey embryoid body cells and mouse hepatocytes in vivo
    Okamura K.; Asahina K.; Fujimori H.; Shimizu-Saito K.; Tanaka Y.; Takase K.; Teramoto K.; Arii S.; Kataoka M.; Soeno Y.; Tateno C.; Yoshizato K.; Teraoka H.
    The International Society for Stem Cell Research 3rd Annual Meeting, 24 Jun. 2005
  • Differentiation of hepatocytes from monkey ES cells in vitro and cell fusion between monkey embryoid body cells and mouse hepatocytes in vivo
    Okamura K.; Asahina K.; Shimizu-Saito K.; Tanaka Y.; Takase K.; Teramoto K.; Arii S.; Tateno C.; Yoshizato K.; Teraoka H.
    第58回日本細胞生物学会, 16 Jun. 2005
  • ヒト臍帯血由来細胞の肝細胞への誘導と細胞起源に関する検討
    柿沼晴; 田中雄二郎; 坂本直哉; 朝比奈欣治; 有井滋樹; 立野知世; 吉里勝利; 水島優子; 中内啓光; 寺岡弘文; 渡辺守
    第41回日本肝臓学会総会, 16 Jun. 2005
  • Phosphorylation of histone H2AX at M phase in human cells without DNA damage response
    Ichijima Y.; Sakasai R.; Okita N.; Asahina K.; Teraoka H.
    第58回日本細胞生物学会, 15 Jun. 2005
  • 正常肝臓からFACSによる肝臓の筋繊維芽細胞の分離とその細胞特性の解析
    小川智弘; 立野知世; 朝比奈欣治; 河田則文; 小原政信; 吉里勝利
    第78回日本組織培養学会, 26 May 2005
  • 肝細胞移植の供給源としてのES細胞の有用性
    神代祐至; 寺本研一; 入江工; 齊藤佳子; 朝比奈欣治; 寺岡弘文; 有井滋樹
    第105回日本外科学会, 13 May 2005
  • 臍帯血有核細胞より胆管上皮細胞を分化誘導する試み
    入江工; 寺本研一; 神代祐至; 柿沼晴; 朝比奈欣治; 齊藤佳子; 久保田俊郎; 寺岡弘文; 有井滋樹
    第105回日本外科学会, 13 May 2005
  • 肝特異的Cyp7a1遺伝子のプロモーター領域のメチル化解析
    西田知弘; 池田玲子; 藤森浩彰; 沖田直之; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第4回日本再生医療学会, 01 Mar. 2005
  • 臍帯血有核細胞より胆管上皮細胞を分化誘導する試み
    入江工; 寺本研一; 神代祐至; 有井滋樹; 柿沼晴; 田中雄二郎; 久保田俊郎; 朝比奈欣治; 齊藤佳子; 寺岡弘文
    第4回日本再生医療学会, 01 Mar. 2005
  • 肝細胞移植治療を目指したカニクイザルES細胞からの肝細胞分化誘導
    岡村健太郎; 朝比奈欣治; 田中雄二郎; 高瀬浩造; 片岡美穂; 添野吉徳; 立野知世; 吉里勝利; 齊藤佳子; 寺岡弘文
    第4回日本再生医療学会, 01 Mar. 2005
  • Finding of a liver-specific gene, Cyp7a1, and verification of hepatocyte differentiation in embryoid bodies formed from mouse ES cells.
    Asahina K; Fujimori H; Shimizu-Saito K; Kumashiro Y; Okamura K; Tanaka Y; Teramoto K; Arii S; Teraoka H
    Keystone Symposium, 11 Feb. 2005
  • マウスES細胞からの肝細胞分化の証明およびES細胞由来肝細胞の移植効果
    朝比奈欣治; 神代祐至; 藤森浩彰; 齊藤佳子; 寺本研一; 有井滋樹; 寺岡弘文
    第23回Cytoprotection研究会, 04 Feb. 2005
  • Purification of myofibroblasts from normal adult rat livers by fluorescence-activated cell sorting and their propagation
    Ogawa T.; Tateno C.; Asahina K.; Kawada N.; Obara M.; Yoshizato K.
    Hiroshima University 21st Century COE Program, 16 Dec. 2004
  • 肝特異的遺伝子Cyp7a1によるマウスES細胞から分化誘導した肝細胞の可視化
    藤森浩彰; 齊藤佳子; 寺岡弘文; 朝比奈欣治
    第27回日本分子生物学会年会, 09 Dec. 2004
  • マウス肝発生におけるMAT1A遺伝子プロモーター領域のCpGメチル化パターンの解析
    池田玲子; 西田友弘; 酒井綾子; 逆井良; 齊藤佳子; 朝比奈欣治; 堀川三郎; 寺岡弘文
    第27回日本分子生物学会年会, 09 Dec. 2004
  • 複製フォークの進行に伴うDNA二本鎖切断に対するDNA-PKの挙動
    逆井良; 市島洋介; 沖田直之; 朝比奈欣治; 寺岡弘文
    第27回日本分子生物学会年会, 09 Dec. 2004
  • Expression of Cyp7a1 demonstrates hepatocyte differentiation from mouse embryonic stem cells.
    Asahina K
    17th Naito Conference, 17 Nov. 2004
  • Expression profiles and CpG methylation patterns of MAT1A gene in mouse developing liver
    Shimizu-Saito K.; Ikeda R.; Isobe N.; Yoshii D.; Sakasai R.; Asahina K.; Horikawa S.; Teraoka H.
    第77回日本生化学会大会, 15 Oct. 2004
  • Isolation of hepatocyte-like cells from mouse embryoid body cells
    Kumashiro Y.; Teramoto K.; Shimizu-Saito K.; Asahina K.; Teraoka H.; Arii S.
    XX International congress of the transplantation society, 05 Sep. 2004
  • マウスES細胞由来肝細胞の濃縮と奇形腫発生の予防
    神代祐至; 寺本研一; 田中雄二郎; 齊藤佳子; 朝比奈欣治; 寺岡弘文; 有井滋樹
    第59回日本消化器外科学会定期学術総会, 23 Jul. 2004
  • ヒト臍帯血細胞の肝細胞への誘導と細胞移植
    柿沼晴; 田中雄二郎; 朝比奈欣治; 神代祐至; 齊藤佳子; 有井滋樹; 立野知世; 吉里勝利; 寺岡弘文; 渡辺守
    第25回日本炎症・再生医学会, 13 Jul. 2004
  • ラット小型肝細胞の遺伝子発現および形態学的解析
    立野知世; 山崎ちひろ; 朝比奈欣治; 吉里勝利
    第11回肝細胞研究会, 02 Jul. 2004
  • カニクイザルES細胞からの胚様体形成および単層培養による肝細胞分化誘導
    岡村健太郎; 藤森浩彰; 齊藤佳子; 朝比奈欣治; 田中雄二郎; 高瀬浩造; 寺岡弘文
    第11回肝細胞研究会, 02 Jul. 2004
  • 肝臓特異的遺伝子Cyp7a1によるマウスES細胞から肝細胞分化の証明
    朝比奈欣治; 神代祐至; 岡村健太郎; 藤森浩彰; 齊藤佳子; 田中雄二郎; 寺本研一; 有井滋樹; 寺岡弘文
    第11回肝細胞研究会, 02 Jul. 2004
  • Differentiation of hepatocytes and dendritic cells from umbilical cord blood cells under alternative culture conditions
    Teraoka H.; Ozeki R.; Okamura K.; Shimizu-Saito K.; Asahina K.; Kakinuma S.; Tanaka Y.; Kumashiro Y.; Teramoto K.; Arii S.
    The International Society for Stem Cell Research 2nd Annual Meeting, 12 Jun. 2004
  • Transplantation of human umbilical cord blood cells to injured liver
    Kakinuma S.; Tanaka Y.; Asahina K.; Okamura K.; Soeno Y.; Tateno C.; Yoshizato K.; Teramoto K.; Arii S.; Sakamoto N.; Teraoka H.; Watanabe M.
    Digestive Disease Week, 18 May 2004
  • マウスES細胞由来肝細胞の単離と奇形腫発生の予防
    神代祐至; 鎮西亮子; 寺本研一; 田中雄二郎; 齊藤佳子; 朝比奈欣治; 寺岡弘文; 有井滋樹
    第104回外科学会, 09 Apr. 2004
  • ヒト臍帯血由来細胞を用いた肝障害マウスへの細胞移植に関する検討
    柿沼晴; 田中雄二郎; 朝比奈欣治; 立野知世; 吉里勝利; 寺本研一; 有井滋樹; 渡辺守; 寺岡弘文
    第3回日本再生医療学会, 25 Mar. 2004
  • 接着培養したマウスES細胞由来胚様体には臓側内胚葉だけでなく肝細胞も分化誘導される
    朝比奈欣治; 神代祐至; 寺本研一; 有井滋樹; 田中雄二郎; 齊藤佳子; 寺岡弘文
    第3回日本再生医療学会, 25 Mar. 2004
  • マウスES細胞由来肝細胞の単離と奇形腫発生の予防
    神代祐至; 鎮西亮子; 寺本研一; 田中雄二郎; 齊藤佳子; 朝比奈欣治; 寺岡弘文; 有井滋樹
    第22回Cytoprotection研究会, 27 Feb. 2004
  • 培養肝星細胞株LI90による樹状細胞分化誘導と生物学的意義の探究
    尾関理恵; 齊藤佳子; 朝比奈欣治; 柿沼晴; 田中雄二郎; 寺本研一; 有井滋樹; 寺岡弘文
    第17回肝類洞壁細胞研究会, 14 Dec. 2003
  • 肝臓筋繊維芽細胞のFACSによる分離とその細胞特性の解析
    小川智弘; 朝比奈欣治; 立野知世; 小原政信; 吉里勝利
    第17回肝類洞壁細胞研究会, 14 Dec. 2003
  • DNA2重鎖切断修復に関わるNHEJ因子のアポトーシス誘導時における挙動
    市島陽介; 逆井良; 沖田直之; 朝比奈欣治; 寺岡弘文
    第26回日本分子生物学会, 11 Dec. 2003
  • マウスES細胞由来胚様体から分化した肝細胞の性状と単離培養
    朝比奈欣治; 神代祐至; 寺本研一; 有井滋樹; 田中雄二郎; 齊藤佳子; 寺岡弘文
    第26回日本分子生物学会, 11 Dec. 2003
  • 培養肝星細胞株LI90が分泌する樹状細胞分化誘導因子の解析
    尾関理恵; 柿沼晴; 齊藤佳子; 朝比奈欣治; 田中雄二郎; 寺本研一; 有井滋樹; 安水洸彦; 寺岡弘文
    第24回日本炎症・再生医学会, 26 Nov. 2003
  • Purification of ES cell-derived parenchymal cells
    神代祐至; 原譲; 寺本研一; 有井滋樹; 鎮西亮子; 田中雄二郎; 高瀬浩造; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    DDW-2003, 15 Oct. 2003
  • Generation of hepatocyte-like cells from extra-hepatic sources including monkey ES cells and human umbilical cord blood
    Asahina K; Okamura K; Shimizu-Saito K; Ozeki R; Kakinuma S; Tanaka Y; Kumashiro Y; Teramoto K; Arii S; Takase K; Teraoka H
    第76回日本生化学会大会, 15 Oct. 2003
  • Myofibroblastと思われる細胞のFACSによる解析・分離
    小川智弘; 朝比奈欣治; 立野知世; 小原政信; 吉里勝利
    第10回肝細胞研究会, 12 Jul. 2003
  • カニクイザルES細胞からin vitroおよびin vivoにおける肝細胞分化
    岡村健太郎; 藤森浩彰; 柿沼晴; 田中雄二郎; 高瀬浩造; 添野吉徳; 立野知世; 吉里勝利; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第10回肝細胞研究会, 11 Jul. 2003
  • マウスES細胞から肝構成細胞への分化誘導
    神代祐至; 齊藤佳子; 寺本研一; 有井滋樹; 柿沼晴; 田中雄二郎; 朝比奈欣治; 寺岡弘文
    第10回肝細胞研究会, 11 Jul. 2003
  • 臍帯血由来細胞の肝実質細胞への誘導と細胞移植
    柿沼晴; 田中雄二郎; 齊藤佳子; 尾関理恵; 朝比奈欣治; 寺本研一; 有井滋樹; 渡辺守; 安水洸彦; 寺岡弘文
    第10回肝細胞研究会, 11 Jul. 2003
  • マウスES細胞からの肝細胞分化誘導と単離肝細胞の解析
    神代祐至; 寺本研一; 原譲; 有井滋樹; 齊藤佳子; 鎮西亮子; 朝比奈欣治; 寺岡弘文; 田中雄二郎; 高瀬浩造
    第103回日本外科学会, 04 Jun. 2003
  • ES細胞および臍帯血から肝細胞への分化誘導
    寺岡弘文; 齊藤佳子; 朝比奈欣治; 柿沼晴; 鎮西亮子; 田中雄二郎; 神代祐至; 寺本研一; 有井滋樹; 安水洸彦
    第44回日本哺乳動物卵子学会, 17 May 2003
  • カニクイザルES細胞からの肝細胞の分化誘導
    岡村健太郎; 藤森浩彰; 柿沼晴; 田中雄二郎; 高瀬浩造; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第56回日本細胞生物学会, 14 May 2003
  • Differentiation of mouse ES cells into hepatic parenchymal and nonparenchymal cells.
    Asahina K; Kumashiro Y; Shimizu-Saito K; Toyoda K; Tanaka Y; Hara Y; Teramoto K; Arii S; Teraoka H
    Keystone Symposium, 31 Mar. 2003
  • マウスES細胞由来肝実質細胞の単層培養による解析
    神代祐至; 原譲; 寺本研一; 有井滋樹; 鎮西亮子; 田中雄二郎; 高瀬浩造; 齊藤佳子; 朝比奈欣治; 寺岡弘文
    第2回日本再生医療学会, 11 Mar. 2003
  • ヒトDNAリガーゼIの構造と機能に関する研究
    沖田直之; 朝比奈欣治; 田沼靖一; 寺岡弘文
    第25回日本分子生物学会年会, 11 Dec. 2002
  • マウスES細胞から肝非実質細胞への分化誘導の検討
    豊田香織; 齊藤佳子; 鎮西亮子; 柿沼晴; 田中雄二郎; 原譲; 寺本研一; 有井滋樹; 小林進; 朝比奈欣治; 寺岡弘文
    第75回日本生化学会大会, 15 Oct. 2002
  • Expression of STAP (stellate cell activation-associated protein) in the visceral fibroblasts of rats
    Nakatani K.; Nakajima Y.; Kawada N.; Asahina K.; Yoshizato K.
    6th Joint Meeting of the Japan Society of histochemistry and cytochemistry and the Histochemical Society, 20 Jul. 2002
  • ラット増殖性小型肝細胞に発現する遺伝子の解析
    塩川美穂; 朝比奈欣治; 立野知世; 山崎ちひろ; 荒谷彰男; 大西千元; 吉実康美; 吉里勝利
    第9回肝細胞研究会, 12 Jul. 2002
  • マウスES細胞からのin vitroとin vivoにおける肝細胞分化誘導
    齊藤佳子; 鎮西亮子; 豊田香織; 柿沼晴; 田中雄二郎; 原譲; 神代祐至; 寺本研一; 有井滋樹; 朝比奈欣治; 寺岡弘文
    第9回肝細胞研究会, 12 Jul. 2002
  • マウスを媒体としたヒト肝細胞増殖法の開発およびその機能解析
    立野知世; 朝比奈欣治; 片岡美穂; 吉実康美; 齊藤直美; 浅原利正; 日野裕史; 古川敏紀; 吉里勝利
    第9回肝細胞研究会, 12 Jul. 2002
  • プロテオミクスを用いた新遺伝子stapの発現とその蛋白機能解析
    河田則文; 朝比奈欣治; 吉里勝利
    第88回日本消化器病学会総会, 25 Apr. 2002
  • Molecular and cellular analysis of stellate cell activation-associated protein (STAP)
    Kawada N.; Asahina K.; Yoshizato K.
    37th annual meeting of the European association for the study of the liver, 19 Apr. 2002
  • Urokinase Plasminogen Activatorトランスジェニックマウスを用いたヒト肝細胞置換キメラマウスの作製
    立野知世; 朝比奈欣治; 吉実康美; 齊藤直美; 古川敏紀; 吉里勝利
    第79回日本生理学会, 28 Mar. 2002
  • 肝臓の再生と発生におけるプレイオトロフィンの役割
    朝比奈欣治; 佐藤玄; 山崎ちひろ; 片岡美穂; 塩川美穂; 片山繁; 立野知世; 吉里勝利
    第15回肝類洞壁細胞研究会, 15 Dec. 2001
  • 新しい蛋白質STAPのラットおよびヒト肝臓における発現とその機能解析
    河田則文; Dan Bach Kristensen; 朝比奈欣治; 吉里勝利
    第24回日本分子生物学会, 10 Dec. 2001
  • Isolation of a stellate cell activation-associated protein (STAP) with peroxidase activity from rat hepatic stellate cells
    Kawada N.; Kristensen BD; Asahina K.; Nakatani K.; Minamiyama Y.; Seki S.; Yoshizato K.
    52nd annual meeting for American association for the study of liver disease, 12 Nov. 2001
  • Proteomics in hepatic fibrosis
    Kawada N.; Kristensen BD; Asahina K.; Yoshizato K.
    36th of the European association for the study of the liver, 12 Oct. 2001
  • ラット小型肝細胞特異的に発現する遺伝子のクローニング
    朝比奈欣治; 塩川美穂; 立野知世; 片山繁; 山崎ちひろ; 荒谷彰男; 大西千元; 吉里勝利
    第8回肝細胞研究会, 30 Jun. 2001
  • 新しい蛋白質STAPの星細胞における発現とその機能解析
    河田則文; Dan Back Kristensen; 朝比奈欣治; 吉里勝利
    第8回肝細胞研究会, 29 Jun. 2001
  • The molecular profiles of stellate cell activation by proteomics
    Kawada N.; Seki S.; Asahina K.; Kristensen DB; Yoshizato K.
    51st annual meeting for American association for the study of liver disease, 31 Oct. 2000
  • Analysis of proteins dominantly expressed in stellate cells of activated phenotype
    Kawada N.; Seki S.; Kaneda K.; Asahina K.; Kristensen DB; Yoshizato K.
    10th International symposium on cells of the hepatic sinusoid, 03 Sep. 2000
  • 肝障害におけるプレイオトロフィンの発現
    佐藤玄; 朝比奈欣治; 山崎ちひろ; 立野知世; 吉里勝利
    第3回日本組織工学会, 01 Jul. 2000
  • D-ガラクトサミン投与ラット肝臓におけるヘパリン結合性増殖因子pleiotrophinの発現様式
    朝比奈欣治; 佐藤玄; 立野知世; 吉里勝利
    第7回肝細胞研究会, 24 Jun. 2000
  • ラット表皮の発生および分化にともない発現する新規遺伝子、KDAPについて
    Florent Sahuc; 大水総一; 稲松睦; 松崎貴; 朝比奈欣治; 佐々木正和; 小原政信; 吉里勝利
    日本研究皮膚科学会第24回学術大会, 31 Jul. 1999
  • 肝繊維化に伴う細胞外マトリックス関連遺伝子発現の変化
    立秋優子; 朝比奈欣治; 小橋俊彦; 立野知世; 小原政信; 吉里勝利
    第6回肝細胞研究会, 04 Jun. 1999
  • Epidermal cells express type I collagen genes during anuran larval development in vivo and in vitro
    Utoh R.; Asahina K.; Obara M.; Yoshizato K.
    The Frontiers of the Biology of Amphibia, 23 Mar. 1999
  • Unique expression of genes of type I and type II collagens in apical epidermal cap, blastema, muscle and cartilage of regenerating newt limb.
    Asahina K; Obara M; Yoshizato K
    The Frontiers of the Biology of Amphibia, the International Symposium, 23 Mar. 1999
  • アカハライモリ前肢再生芽形成におけるI型およびII型コラーゲン遺伝子の発現
    朝比奈欣治; 小原政信; 吉里勝利
    日本動物学会第69回大会, 28 Sep. 1998
  • 無尾両生類の変態時での小腸におけるa1(I)、a2(I)コラーゲン遺伝子の発現
    鵜頭理恵; 朝比奈欣治; 小原政信; 吉里勝利
    日本動物学会第69回大会, 27 Sep. 1998
  • イモリ前肢再生芽形成とI型及びII型コラーゲンの発現について
    朝比奈欣治
    第18回発生懇話会, 18 Jul. 1998
  • A possible involvement of epidermal cells in the formation of thick lamella of collagen type I in the anuran larval mesenchyme
    Utoh R.; Asahina K.; Obara M.; Yoshizato K.
    4th CGGH International Symposium, Frontiers in Matrix Biology, 20 Jun. 1998
  • Spatiotemporal expressions of a1(I) and a1(II) collagen genes during newt forelimb regeneration
    Asahina K; Obara M; Yoshizato K
    4th CGGH International Symposium, Frontiers in Matrix Biology, 20 Jun. 1998
  • ウシガエル幼生皮膚のコラーゲン層は、外胚葉・中胚葉由来の細胞から作られる
    鵜頭理恵; 朝比奈欣治; 小原政信; 吉里勝利
    日本動物学会中四国支部第55回大会, 23 May 1998
  • イモリ再生芽でのa1(I)コラーゲンmRNAの発現の変化とその局在
    朝比奈欣治; 末吉晶子; 大房健; 小原政信; 吉里勝利
    日本動物学会第68回大会, 04 Oct. 1997
  • イモリa1(I)コラーゲンの分子構造
    末吉晶子; 朝比奈欣治; 小原政信; 吉里勝利
    日本動物学会中四国支部第54回大会, 17 May 1997
  • 無尾両生類a1(I)及びa2(I)コラーゲンのcDNAクローニングと変態時における部域特異的な発現調節
    朝比奈欣治; 大房健; 小原政信; 吉里勝利
    マトリックス研究会第44回大会, 28 Mar. 1997
  • ウシガエル幼生のa1(I)及びa2(I)コラーゲン遺伝子の部域特異的及びホルモン依存的発現調節
    朝比奈欣治; 大房健; 小原政信; 吉里勝利
    日本発生生物学会第29回大会, 24 May 1996
  • ウシガエルa1(I)及びa2(I)コラーゲンcDNAの構造解析
    朝比奈欣治; 大房健; 小原政信; 吉里勝利
    日本動物学会中四国支部第53回大会, 19 May 1996
  • ウシガエルコラーゲン遺伝子の甲状腺ホルモンによる部域特異的発現調節
    朝比奈欣治; 世森重信; 大房健; 吉里勝利
    日本動物学会第65回大, 08 Oct. 1994
■ Courses
  • Anatomy and physiology III
    2025, Present, Shigaken Saiseikai Nursing School
  • Summer program for undergraduate students
    2023, Present, Shiga University of Medical Science
  • Research practice course
    2023, Present, Shiga University of Medical Science
  • Modern society and science
    2023, Present, Shiga University of Medical Science
  • Infectious diseases
    2022, Present, Otsu Medical Association Nursing School
  • Introduction of medical science
    2022, Present, Shiga University of Medical Science
  • Medical science
    2022, Present, Shiga University of Medical Science
  • Seminar series
    2021, Present, Shiga University of Medical Science
  • Methods in Cellular and Clinical Pathology
    2020, 2021, University of Southern California
  • Graduate student seminar in Pathology
    2019, 2021, University of Southern California
  • Summer program in diabetes and obesity research (SPIDOR/NIH/NIDDK)
    2018, 2021, University of Southern California
  • Frontiers of Pathology
    2009, 2021, University of Southern California
  • System Physiology and Disease II
    2012, 2017, University of Southern California
  • Stem Cell Biology and Medicine
    2010, 2012, University of Southern California
  • Regenerative medicine
    2003, 2006, Tokyo Medical and Dental University
  • Biochemistry
    2002, 2003, Tokyo Medical and Dental University
  • Stem cells
    2002, Tokyo Medical and Dental University
  • Biology
    1997, 1998, Hiroshima Dental Hygienist School
■ Affiliated academic society
  • 2024, Present
    Hepatic Sinusoidal Research Japan
  • 2022, Present
    The Japanese Society for the Research of Hepatic Cells
  • 2009, Present
    American Association for the Study of Liver Diseases (AASLD)
  • 2007, Present
    American Society for Biochemistry and Molecular Biology (ASBMB)
■ Research Themes
  • Liver fibrosis
    2025, 2028
  • Crosstalk of liver mesothelial cells and peritoneal macrophages
    基盤研究(B)
    Shiga University of Medical Science
    Apr. 2022, Mar. 2025
  • Activation of hepatic stellate cells
    Apr. 2022, Mar. 2025
  • Roles of lysophosphatidic acid in alcoholic liver disease
    NIAAA
    Jan. 2019, Dec. 2021
  • Live imaging of capsular fibrosis.
    2020, 2021
  • Dissection of Glisson’s capsule in alcohol induced liver injury
    NIAAA
    Aug. 2016, Jul. 2019
  • Role of lysophosphatidic acid in alcoholic steatosis.
    2017, 2018
  • Contribution of the mesothelium to alcohol-induced liver fibrosis
    NIAAAA
    Sep. 2011, Jul. 2017
  • Identification and genesis of tumor-initiating stem cell-like cells in alcohol-promoted pancreatic adenocarcinoma.
    2016, 2017
  • Identification of pancreatic cancer stem cells.
    2016, 2017
  • Role of the Hippo transducer TAZ in mesothelial-mesenchymal transition.
    2014, 2015
  • Contribution of the liver mesothelium to liver fibrosis.
    2011, 2012
  • Hepatic stellate cell precursors in developing and fibrotic livers.
    2009, 2010
  • Formation of asymmetric embryoid body
    Tokyo Medical and Dental University
    2006, 2007
  • Studies of regenerative medicine on differentiation into hepatic and bile duct cells for preclinical trial to surgery
    Grant-in-Aid for Scientific Research (B)
    Tokyo Medical and Dental University
    2006, 2007
  • DNA double strand break in embryonic stem cells
    Tokyo Medical and Dental University
    2006, 2007
  • Hepatic differentiation of embryonic stem cells
    tokyo Medical and Dental University
    2005, 2006
  • Hepatic cell transplantation for liver disease
    Tokyo Medical and Dental University
    2004, 2005
  • Treatment of liver failure by transplantation of hepatocytes derived from mouse and monkey ES cells and human umbilical cord blood
    Grant-in-Aid for Scientific Research (B)
    Tokyo medical and Dental University
    2004, 2005
  • Hepatic differentiation from monkey ES cells and cord blood cells
    萌芽研究
    Tokyo Medical and Dental University
    2003, 2005
■ Social Contribution Activities
  • Shiga-rike
    organizing_member
    2024, Present
  • Open campus
    organizing_member
    Shiga University of Medical Science, 2023, Present
  • Collaboration of high school and university
    organizing_member
    Shiga University of Medical Science, 2023, Present
  • Support of studying abroad from Shiga
    organizing_member
    2024
■ Others
  • Senior radiation protection supervisor
    2023