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HIRATA Takako
Officer

Researcher information

■ Degree
  • 博士(医学), 京都大学
■ Research Keyword
  • 分子生物学
  • 細胞生物学
  • 免疫学
■ Field Of Study
  • Life sciences/Immunology

Career

■ Educational Background
  • 1995
    Kyoto University, 医学研究科, 内科系
  • 1987
    Kyoto University, Faculty of Medicine, Department of Medical Science

Research activity information

■ Paper
  • Transduction of Batf family members provides distinct functions to mouse CD8+ T cells.
    Kenta Kondo; Mina Kumode; Hiroki Satooka; Koji Terada; Yusuke Sano; Nobuhito Nitta; Daisuke Okuzaki; Kensuke Takada; Takako Hirata; Hidetaka Kosako; Akira Andoh; Makoto Murata; Yasutoshi Agata
    International immunology, 17 Feb. 2026, Refereed
  • Intravenous anesthetic propofol suppresses T cell-dependent antibody production in mice.
    Susumu Hiraoka; Hiroki Satooka; Hirotoshi Kitagawa; Takako Hirata
    Journal of anesthesia, 20 Jun. 2025, Refereed
  • ROS-dependent SOCS3 upregulation disrupts regulatory T cell stability during autoimmune disease development
    Hiroki Satooka; Yuzuki Nakamura; Takako Hirata
    Redox Biology, Mar. 2025, Refereed
  • Moesin deficiency leads to lupus-like nephritis with accumulation of CXCL13-producing patrolling monocytes
    Satoko Ichioka; Hiroki Satooka; Yoshihiro Maruo; Takako Hirata
    Biochemical and Biophysical Research Communications, Apr. 2024, Refereed
  • Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model.
    Koji Terada; Kenta Kondo; Hirohito Ishigaki; Ayaka Nagashima; Hiroki Satooka; Seiji Nagano; Kyoko Masuda; Teruhisa Kawamura; Takako Hirata; Kazumasa Ogasawara; Yasushi Itoh; Hiroshi Kawamoto; Yasutoshi Agata
    Molecular therapy oncolytics, 17 Mar. 2022, Refereed
  • The ERM protein moesin regulates natural killer cell homeostasis in vivo.
    Hiroki Satooka; Makoto Matsui; Satoko Ichioka; Yuzuki Nakamura; Takako Hirata
    Cellular immunology, Jan. 2022, Refereed, Not invited
  • Alteration in endometrial helper T‐cell subgroups in chronic endometritis
    Jun Kitazawa; Fuminori Kimura; Akiko Nakamura; Aina Morimune; Tetsuro Hanada; Tsukuru Amano; Shunichiro Tsuji; Kyoko Kasahara; Hiroki Satooka; Takako Hirata; Ryoji Kushima; Takashi Murakami
    American Journal of Reproductive Immunology, 25 Nov. 2020, Refereed, Not invited, URL
  • Citrullinated fibrinogen is a target of auto-antibodies in interstitial lung disease in mice with collagen-induced arthritis.
    Tomomi Sato; Hiroki Satooka; Satoko Ichioka; Yoshihiro Maruo; Takako Hirata
    International immunology, 28 Jul. 2020, Refereed, Not invited
  • A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.
    Makoto Matsui; Daisuke Nagakubo; Hiroki Satooka; Takako Hirata
    Biochemical and biophysical research communications, 04 Jun. 2020, Refereed, Not invited
  • Characterization of tumour-infiltrating lymphocytes in a tumour rejection cynomolgus macaque model.
    Hiroki Satooka; Hirohito Ishigaki; Kagefumi Todo; Koji Terada; Yasutoshi Agata; Yasushi Itoh; Kazumasa Ogasawara; Takako Hirata
    Scientific reports, 21 May 2020, Refereed, Not invited
  • mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.
    D Thumkeo; Y Katsura; Y Nishimura; P Kanchanawong; K Tohyama; T Ishizaki; S Kitajima; C Takahashi; T Hirata; N Watanabe; M F Krummel; S Narumiya
    Science advances, Jan. 2020, Refereed, Not invited
  • CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon.
    Kazuhiko Matsuo; Daisuke Nagakubo; Shinya Yamamoto; Akiko Shigeta; Shuta Tomida; Mitsugu Fujita; Takako Hirata; Ikuo Tsunoda; Takashi Nakayama; Osamu Yoshie
    Journal of immunology (Baltimore, Md. : 1950), 15 Jan. 2018, Refereed, Not invited
  • PKN1はリンパ球の細胞運動・トラフィッキングを制御する
    窪内 康二; 團野 紗莉; 野町 昭; 平田 多佳子; 松尾 一彦; 中山 隆志; 佐藤 亮介; 杉浦 麗子; 阿部 学; 崎村 建司; 若菜 茂晴; 大崎 博之; 鴨志田 伸吾; 向井 秀幸
    生命科学系学会合同年次大会, Dec. 2017, Refereed, Not invited
  • The ERM Protein Moesin Regulates CD8(+) Regulatory T Cell Homeostasis and Self-Tolerance
    Hiroki Satooka; Daisuke Nagakubo; Tomomi Sato; Takako Hirata
    JOURNAL OF IMMUNOLOGY, Nov. 2017, Refereed, Not invited
  • Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN1
    Rana Mashud; Akira Nomachi; Akihide Hayakawa; Koji Kubouchi; Sally Danno; Takako Hirata; Kazuhiko Matsuo; Takashi Nakayama; Ryosuke Satoh; Reiko Sugiura; Manabu Abe; Kenji Sakimura; Shigeharu Wakana; Hiroyuki Ohsaki; Shingo Kamoshida; Hideyuki Mukai
    SCIENTIFIC REPORTS, Aug. 2017, Refereed, Not invited
  • Moesin regulates neutrophil rolling velocity in vivo
    Masanori Matsumoto; Takako Hirata
    CELLULAR IMMUNOLOGY, Jun. 2016, Refereed, Not invited
  • Upregulated CCL28 expression in the nasal mucosa in experimental allergic rhinitis: Implication for CD4(+) memory T cell recruitment
    Daisuke Nagakubo; Osamu Yoshie; Takako Hirata
    CELLULAR IMMUNOLOGY, Apr. 2016, Refereed, Not invited
  • Glycosylation Status of CD43 Protein Is Associated with Resistance of Leukemia Cells to CTL-Mediated Cytolysis
    Kana Hasegawa; Satomi Tanaka; Fumihiro Fujiki; Soyoko Morimoto; Katsuhiko Nakano; Hiroko Kinoshita; Atsushi Okumura; Yuka Fujioka; Rika Urakawa; Hiroko Nakajima; Naoya Tatsumi; Jun Nakata; Satoshi Takashima; Sumiyuki Nishida; Akihiro Tsuboi; Yoshihiro Oka; Yusuke Oji; Eiji Miyoshi; Takako Hirata; Atsushi Kumanogoh; Haruo Sugiyama; Naoki Hosen
    PLOS ONE, Mar. 2016, Refereed, Not invited
  • A novel splice variant of human L-selectin encodes a soluble molecule that is elevated in serum of patients with rheumatic diseases
    Takako Hirata; Takashi Usui; Shio Kobayashi; Tsuneyo Mimori
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2015, Refereed, Not invited
  • Moesin Controls Clathrin-Mediated S1PR1 Internalization in T Cells
    Akira Nomachi; Masanori Yoshinaga; Jaron Liu; Pakorn Kanchanawong; Kiyoshi Tohyama; Dean Thumkeo; Takeshi Watanabe; Shuh Narumiya; Takako Hirata
    PLOS ONE, Dec. 2013, Refereed, Not invited
  • Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase (vol 4, pg 1685, 2013)
    Chengcan Yao; Takako Hirata; Kitipong Soontrapa; Xiaojun Ma; Hiroshi Takemori; Shuh Narumiya
    NATURE COMMUNICATIONS, Sep. 2013, Refereed, Not invited
  • Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis
    Takako Hirata; Akira Nomachi; Kazuo Tohya; Masayuki Miyasaka; Sachiko Tsukita; Takeshi Watanabe; Shuh Narumiya
    INTERNATIONAL IMMUNOLOGY, Nov. 2012, Refereed, Not invited
  • Prostanoids as Regulators of Innate and Adaptive Immunity
    Takako Hirata; Shuh Narumiya
    ADVANCES IN IMMUNOLOGY, VOL 116, 2012, Refereed, Not invited
  • Prostanoid Receptors
    Takako Hirata; Shuh Narumiya
    CHEMICAL REVIEWS, Oct. 2011, Refereed, Not invited, Lead
  • A GPR40 Agonist GW9508 Suppresses CCL5, CCL17, and CXCL10 Induction in Keratinocytes and Attenuates Cutaneous Immune Inflammation
    Tomoko Fujita; Toshiyuki Matsuoka; Tetsuya Honda; Kenji Kabashima; Takako Hirata; Shuh Narumiya
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, Aug. 2011, Refereed, Not invited
  • Prostaglandin E-2-prostoglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression
    Kitipong Soontrapa; Tetsuya Honda; Daiji Sakata; Chengcan Yao; Takako Hirata; Shohei Hori; Toshiyuki Matsuoka; Yoshihiro Kita; Takao Shimizu; Kenji Kabashima; Shuh Narumiya
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2011, Refereed, Not invited
  • P-Selectin Glycoprotein Ligand-1 Negatively Regulates T-Cell Immune Responses
    Masanori Matsumoto; Masayuki Miyasaka; Takako Hirata
    JOURNAL OF IMMUNOLOGY, Dec. 2009, Refereed, Not invited
  • Constitutive Expression of IDO by Dendritic Cells of Mesenteric Lymph Nodes: Functional Involvement of the CTLA-4/B7 and CCL22/CCR4 Interactions
    Toshiharu Onodera; Myoung Ho Jang; Zijin Guo; Mikako Yamasaki; Takako Hirata; Zhongbin Bai; Noriko M. Tsuji; Daisuke Nagakubo; Osamu Yoshie; Shimon Sakaguchi; Osamu Takikawa; Masayuki Miyasaka
    JOURNAL OF IMMUNOLOGY, Nov. 2009, Refereed, Not invited
  • An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation
    Akiko Shigeta; Masanori Matsumoto; Thomas F. Tedder; John B. Lowe; Masayuki Miyasaka; Takako Hirata
    BLOOD, Dec. 2008, Refereed, Not invited
  • Nepmucin/CLM-9, an Ig domain-containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration in vitro
    Soojung Jin; Eiji Umemoto; Toshiyuki Tanaka; Yoshimitsu Shimomura; Kazuo Tohya; Keiji Kunizawa; Bo-Gie Yang; Myoung Ho Jang; Takako Hirata; Masayuki Miyasaka
    FEBS LETTERS, Sep. 2008, Refereed, Not invited
  • CD43 plays both antiadhesive and proadhesive roles in neutrophil rolling in a context-dependent manner
    Masanori Matsumoto; Akiko Shigeta; Masayuki Miyasaka; Takako Hirata
    JOURNAL OF IMMUNOLOGY, Sep. 2008, Refereed, Not invited
  • Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells
    Kazuki N. Sugahara; Takako Hirata; Toshiyuki Tanaka; Shinji Ogino; Mitsuhiro Takeda; Hiroaki Terasawa; Ichio Shimada; Jun-ichi Tamura; Gerdy B. ten Dam; Toin H. van Kuppevelt; Masayuki Miyasaka
    CANCER RESEARCH, Sep. 2008, Refereed, Not invited
  • Identification of novel isoforms of mouse L-selectin with different carboxyl-terminal tails
    Yuko Furukawa; Eiji Umemoto; Myoung Ho Jang; Kazuo Tohya; Masayuki Miyasaka; Takako Hirata
    JOURNAL OF BIOLOGICAL CHEMISTRY, May 2008, Refereed, Not invited
  • CD4(+)CD25(+) regulatory T cells in the small intestinal lamina propria show an effector/memory phenotype
    Zijin Guo; Myoung Ho Jang; Kazuhiro Otani; Zhongbin Bai; Eiji Umemoto; Masanori Matsumoto; Mika Nishiyama; Mikako Yamasaki; Satoshi Ueha; Kouji Matsushima; Takako Hirata; Masayuki Miyasaka
    INTERNATIONAL IMMUNOLOGY, Mar. 2008, Refereed, Not invited
  • P-selectin glycoprotein ligand-1 mediates L-selectin-independent leukocyte rolling in high endothelial venules of peripheral lymph nodes
    Nari Harakawa; Akiko Shigeta; Masahiro Wato; Glenn Merrill-Skoloff; Barbara C. Furie; Bruce Furie; Toshiro Okazaki; Naochika Domae; Masayuki Miyasaka; Takako Hirata
    INTERNATIONAL IMMUNOLOGY, Mar. 2007, Refereed, Not invited
  • CD43 collaborates with P-selectin glycoprotein ligand-1 to mediate E-selectin-dependent T cell migration into inflamed skin
    Masanori Matsumoto; Akiko Shigeta; Yuko Furukawa; Toshiyuki Tanaka; Masayuki Miyasaka; Takako Hirata
    JOURNAL OF IMMUNOLOGY, Feb. 2007, Refereed, Not invited
  • Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow
    E Umemoto; T Tanaka; H Kanda; S Jin; K Tohya; K Otani; T Matsutani; M Matsumoto; Y Ebisuno; MH Jang; M Fukuda; T Hirata; M Miyasaka
    JOURNAL OF EXPERIMENTAL MEDICINE, Jun. 2006, Refereed, Not invited
  • Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments
    KN Sugahara; T Hirata; H Hayasaka; R Stern; T Murai; M Miyasaka
    JOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2006, Refereed, Not invited
  • CCR7 is critically important in intestinal lamina propria for migration of dendritic cells to mesenteric lymph nodes
    MH Jang; N Sougawa; T Tanaka; T Hirata; T Hiroi; K Tohya; ZJ Guo; E Umemoto; Y Ebisuno; BG Yang; JY Seoh; M Lipp; H Kiyono; M Miyasaka
    JOURNAL OF IMMUNOLOGY, Jan. 2006, Refereed, Not invited
  • CD43 functions as a ligand for E-selectin on activated T cells
    M Matsumoto; K Atarashi; E Umemoto; Y Furukawa; A Shigeta; M Miyasaka; T Hirata
    JOURNAL OF IMMUNOLOGY, Dec. 2005, Refereed, Not invited
  • Rolling of Th1 cells via p-selectin glycoprotein ligand-1 stimulates LFA-1-Mediated cell binding to ICAM-1
    K Atarashi; T Hirata; M Matsumoto; N Kanemitsu; M Miyasaka
    JOURNAL OF IMMUNOLOGY, Feb. 2005, Refereed, Not invited, Corresponding
  • Human P-selectin glycoprotein ligand-1 (PSGL-1) interacts with the skin-associated chemokine CCL27 via sulfated tyrosines at the PSGL-1 amino terminus
    T Hirata; Y Furukawa; BG Yang; K Hieshima; M Fukuda; R Kannagi; O Yoshie; M Miyasaka
    JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2004, Refereed, Not invited
  • Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling
    H Kanda; T Tanaka; M Matsumoto; E Umemoto; Y Ebisuno; M Kinoshita; M Noda; R Kannagi; T Hirata; T Murai; M Fukuda; M Miyasaka
    INTERNATIONAL IMMUNOLOGY, Sep. 2004, Refereed, Not invited
  • Hyaluronan oligosaccharides and tumor progression
    KN Sugahara; T Hirata; T Murai; M Miyasaka
    TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, May 2004, Not refereed, Not invited
  • Lymphocyte homing to the skin
    Takako Hirata; Barbara C. Furie; Bruce Furie
    Lymphocyte Homing to the Skin: Immunology, Immunopathology, and Therapeutic Perspectives, 01 Jan. 2004
  • P-, E-, and L-selectin mediate migration of activated CD8(+) T lymphocytes into inflamed skin
    T Hirata; BC Furie; B Furie
    JOURNAL OF IMMUNOLOGY, Oct. 2002, Refereed, Not invited, Lead
  • P-selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration
    T Hirata; G Merrill-Skoloff; M Aab; J Yang; BC Furie; B Furie
    JOURNAL OF EXPERIMENTAL MEDICINE, Dec. 2000, Refereed, Not invited, Lead
  • Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration
    J Yang; T Hirata; K Croce; G Merrill-Skoloff; B Tchernychev; E Williams; R Flaumenhaft; BC Furie; B Furie
    JOURNAL OF EXPERIMENTAL MEDICINE, Dec. 1999, Refereed, Not invited, Lead
  • Identification of domains conferring ligand binding specificity to the prostanoid receptor - Studies on chimeric prostacyclin/prostaglandin D receptors
    T Kobayashi; M Kiriyama; T Hirata; M Hirata; F Ushikubi; S Narumiya
    JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 1997, Refereed, Not invited
  • Two thromboxane A(2) receptor isoforms in human platelets - Opposite coupling to adenylyl cyclase with different sensitivity to Arg(60) to Leu mutation
    T Hirata; F Ushikubi; A Kakizuka; M Okuma; S Narumiya
    JOURNAL OF CLINICAL INVESTIGATION, Feb. 1996, Refereed, Not invited, Lead
  • Molecular characterization of a dominantly inherited bleeding disorder with impaired platelet responses to thromboxane A2
    Minoru Okuma; Takako Hirata; Fumitaka Ushikubi; Akira Kakizuka; Shu Narumiya
    Polish Journal of Pharmacology, 1996, Refereed, Not invited
  • ARG(60) TO LEU MUTATION OF THE HUMAN THROMBOXANE A(2) RECEPTOR IN A DOMINANTLY INHERITED BLEEDING DISORDER
    T HIRATA; A KAKIZUKA; F USHIKUBI; FUSE, I; M OKUMA; S NARUMIYA
    JOURNAL OF CLINICAL INVESTIGATION, Oct. 1994, Refereed, Not invited, Lead
■ MISC
  • Propofol suppresses antibody production against T cell-dependent antigen
    平岡進; 里岡大樹; 平田多佳子; 北川裕利
    日本麻酔科学会学術集会(Web), 2024
  • ナルディライジンに着目した自己免疫性肝炎の病態解明
    吉田晋也; 西清人; 里岡大樹; 大野美紀子; 平田多佳子; 安藤朗; 西英一郎
    日本病態プロテアーゼ学会学術集会プログラム抄録集, 2023
  • Redox-mediated SOCS3 expression in regulatory T cells is involved in the development of autoimmunity
    SATOOKA Hiroki; NAKAMURA Yuzuki; TODO Kagefumi; HIRATA Takako
    日本免疫学会総会・学術集会記録(CD-ROM), 2021
  • Production of secreted form of IgD during immune responses
    TODO Kagefumi; SATOOKA Hiroki; HIRATA Takako
    日本免疫学会総会・学術集会記録(CD-ROM), 2021
  • TおよびB細胞のナルディライジンによる抗体産生調節機構の解明
    茶谷元晴; 茶谷元晴; 藤井貴之; 藤堂景史; 大野美紀子; 西清人; 平田多佳子; 安藤朗; 西英一郎
    日本病態プロテアーゼ学会学術集会プログラム抄録集, 2021
  • カニクイザルの腫瘍拒絶モデルにおける腫瘍浸潤T細胞からの腫瘍殺傷能をもつTCR遺伝子の単離
    寺田晃士; 石垣宏仁; 近藤健太; 長嶋彩花; 里岡大樹; 永野誠治; 増田喬子; 川村晃久; 河本宏; 平田多佳子; 小笠原一誠; 伊藤靖; 縣保年
    日本分子生物学会年会プログラム・要旨集(Web), 2020
  • Phagocytic cells are induced by activation of resting splenic B cells
    ASANO Kyoko; TODO Kagefumi; HIRATA Takako
    日本免疫学会総会・学術集会記録(CD-ROM), 2019
  • Involvement of IgD-expressing cells in type I hypersensitivity
    TODO Kagefumi; ASANO Kyoko; SATOOKA Hiroki; HIRATA Takako
    日本免疫学会総会・学術集会記録(CD-ROM), 2019
  • Redox-mediated signaling in regulatory T cells is involved in the development of autoimmunity
    SATOOKA Hiroki; SATO Tomomi; NAKAMURA Yuzuki; TODO Kagefumi; HIRATA Takako
    日本免疫学会総会・学術集会記録(CD-ROM), 2019
  • 【GPCR研究の最前線2016】 GPCR機能の新展開【免疫・炎症】 スフィンゴシン1-リン酸受容体
    平田 多佳子
    医学のあゆみ, Jan. 2016, Not refereed, Not invited
  • Actin nucleator, mDia1 and mDia3, cooperatively function in T cell receptor signaling-dependent T cell development in thymus
    Dean Thumkeo; Akira Nomachi; Kiyoshi Tohyama; Takako Hirata; Toshimasa Ishizaki; Shuh Narumiya
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014, Refereed, Not invited
  • Roles of mDia, a Rho effector and formin family actin-nucleator, in T cell development
    Thumkeo Dean; Nomachi Akira; Tohyama Kiyoshi; Shinohara Ryota; Hirata Takako; Ishizaki Toshimasa; Narumiya Shuh
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013, Refereed, Not invited
  • リンパ球動態を制御するS1P受容体の内在化機構
    平田 多佳子
    助成研究報告集, 2013, Not refereed, Not invited
  • Prostaglandin E-2-EP2/EP4 signaling promotes Th1 cell differentiation through upregulation of IL-12 receptor beta 2 chain
    Chengcan Yao; Daiji Sakata; Soontrapa Kitipong; Ma Xiaojun; Takako Hirata; Shuh Narumiya
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, Not refereed, Not invited
  • 【分子から個体へと深化する脂質生物学 リピドミクスや脂質イメージングによる局在・機能解析から生体調節系の生理、そして、がん・炎症など疾患の分子機構の理解へ】 脂質メディエーターと受容体 脂質メディエーターは第三世代へ プロスタノイドによる免疫系・神経系制御
    平田 多佳子; 古屋敷 智之
    実験医学, Dec. 2010, Not refereed, Not invited
  • 【広範囲 血液・尿化学検査免疫学的検査[第7版] その数値をどう読むか】 可溶性膜蛋白、接着分子 シアロムチンファミリー
    平田 多佳子
    日本臨床, Jul. 2010, Not refereed, Not invited
  • 制御性T細胞の腫瘍浸潤制御による抗腫瘍免疫の強化
    平田 多佳子
    癌と人, May 2010, Not refereed, Not invited
  • T細胞の炎症局所への動員におけるCD43の生理的役割
    松本 真典; 平田 多佳子
    臨床免疫・アレルギー科, Oct. 2008, Not refereed, Not invited
  • 白血球の血管外遊走におけるCD43分子の機能
    松本 真典; 平田 多佳子
    臨床免疫・アレルギー科, Nov. 2006, Not refereed, Not invited
  • PSGL-1を介するTh1細胞のローリングと活性化
    新 和之; 平田 多佳子; 宮坂 昌之
    臨床免疫, Sep. 2005, Not refereed, Not invited
  • 【広範囲血液・尿化学検査 免疫学的検査 その数値をどう読むか】 可溶性膜蛋白,接着分子 シアロムチンファミリー
    新 和之; 平田 多佳子; 宮坂 昌之
    日本臨床, Aug. 2005, Not refereed, Not invited
  • Sialomucin family
    Kazuyuki Atarashi; Masayuki Miyasaka; Takako Hirata
    Nippon rinsho. Japanese journal of clinical medicine, 2005
  • サイトカインの生理活性 血管系 白血球組織浸潤の分子機構 接着分子,サイトカインとケモカインの関与
    松本 真典; 平田 多佳子; 宮坂 昌之
    医学のあゆみ, Oct. 2004, Not refereed, Not invited
  • 【免疫研究のフロンティア 分子,細胞から個体レベルでの免疫システムの解明とそれが導く新しい臨床応用】 抗原提示細胞とホーミング コンドロイチン硫酸プロテオグリカンと白血球浸潤
    新 和之; 平田 多佳子; 川島 博人; 寒川 延子; 梁 甫伎; 菅原 一樹; 宮坂 昌之
    実験医学, Mar. 2004, Not refereed, Not invited
  • 【ケモカイン・ケモカインレセプターをめぐって】 T細胞の炎症皮膚浸潤におけるセレクチンの役割
    平田 多佳子
    臨床免疫, Oct. 2003, Not refereed, Not invited
  • 【免疫研究の最前線 高次複雑系免疫システムの包括的理解をめざして】 細胞間コミュニケーションのダイナミズム L-セレクチンとCD44の共通リガンドコンドロイチン硫酸プロテオグリカン
    新 和之; 川島 博人; 平田 多佳子; 宮坂 昌之
    蛋白質・核酸・酵素, Dec. 2002, Not refereed, Not invited
  • PSGL-1 is a physiological ligand for E-selectin in mediating TH1 lymphocyte migration.
    T Hirata; G Merrill-Skoloff; M Aab; J Yang; BC Furie; B Furie
    BLOOD, Nov. 2000, Not refereed, Not invited
  • PSGL-1 is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling: In vivo studies of the PSGL-1 deficient mouse.
    K Croce; G Merrill-Skoloff; T Hirata; J Yang; BC Furie; B Furie
    BLOOD, Nov. 1999, Not refereed, Not invited
  • A important role for PSGL-1 in Th1 lymphocyte migration: In vivo studies with PSGL-1-deficient mice.
    T Hirata; G Merrill-Skoloff; E Williams; J Yang; BC Furie; B Furie
    BLOOD, Nov. 1999, Not refereed, Not invited
  • Targeted disruption of the P-selectin glycoprotein ligand-1 gene.
    T Hirata; J Yang; G Merrill-Skoloff; K Croce; B Tchernychev; R Flaumenhaft; BC Furie; B Furie
    BLOOD, Nov. 1998, Not refereed, Not invited
  • 【血液疾患 state of arts(Ver.2)】 病態生理に関する基礎的・臨床的研究 トロンボキサンA2受容体の構造と機能
    平田 多佳子
    医学のあゆみ, Jun. 1998, Not refereed, Not invited
  • 出血と止血の臨床・トピックス 新たに発見された血小板機能異常症 トロンボキサンA2不応症
    平田 多佳子
    Medical Practice, Jun. 1997, Not refereed, Not invited
  • マウス・プロスタグラジン受容体のリガンド結合領域の解析
    小林 拓也; 桐山 通隆; 平田 多佳子; 平田 雅一; 牛首 文隆; 成宮 周
    日本分子生物学会年会プログラム・講演要旨集, 01 Aug. 1996
  • 血小板異常症 血小板トロンボキサンA2レセプター異常症
    平田 多佳子
    Molecular Medicine, Dec. 1995, Not refereed, Not invited
  • トロンボキサンA2受容体異常症の症例
    平田 多佳子; 大熊 稔
    治療学, Oct. 1995, Not refereed, Not invited
  • エイコサノイドとPAFの分子生物学 プロスタノイド受容体
    平田 雅一; 牛首 文隆; 平田 多佳子
    治療学, Oct. 1995, Not refereed, Not invited
  • 血小板トロンボキサンA2レセプターを介するシグナル伝達の異常
    平田 多佳子
    Molecular Medicine, Aug. 1995, Not refereed, Not invited
  • 出血・血栓症とプロスタグランジン
    大熊 稔; 平田 多佳子; 塘 賢二郎
    現代医療, Jul. 1995, Not refereed, Not invited
  • プロスタグランジン受容体
    牛首 文隆; 平田 雅一; 平田 多佳子
    現代医療, Jul. 1995, Not refereed, Not invited
  • IDENTIFICATION OF 2 ISOFORMS OF HUMAN THROMBOXANE A2 RECEPTOR IN PLATELETS
    T HIRATA; A KAKIZUKA; F USHIKUBI; S NARUMIYA; M OKUMA
    THROMBOSIS AND HAEMOSTASIS, Jun. 1995, Not refereed, Not invited
  • 凝固・血小板と情報伝達 トロンボキサンA2受容体異常症
    平田 多佳子; 大熊 稔
    医学のあゆみ, Nov. 1994, Not refereed, Not invited
  • 遺伝性血小板トロンボキサンA2受容体異常症
    平田 多佳子; 大熊 稔
    臨床病理, Nov. 1994, Not refereed, Not invited
  • 情報伝達系の異常と疾患 トロンボキサンA2受容体異常症
    平田 多佳子; 大熊 稔
    医学のあゆみ, Apr. 1994, Not refereed, Not invited
  • 病態生理に関する基礎的・臨床的研究の進歩 トロンボキサンA2受容体の構造と機能
    大熊 稔; 平田 多佳子
    医学のあゆみ, Oct. 1993, Not refereed, Not invited
  • 血小板活性化機構とプロスタグランジン
    大熊 稔; 平田 多佳子; 高山 博史
    治療, May 1991, Not refereed, Not invited
■ Books and other publications
  • Encyclopedia of immunobiology
    Hirata T, Contributor, Blood vascular endothelial adhesion molecules.
    Academic Press, 2016, Not refereed
    9780123742797
  • Lymphocyte homing to the skin-immunology, immunopathology, and therapeutic perspectives
    Hirata T; Furie BC; Furie B, Contributor, Lymphocyte homing to the skin.
    CRC Press, 2005, Not refereed
    9780849325281
  • Hyaluronan-structure, metabolism, biological activities, therapeutic applications
    Sugahara KN; Murai T; Hirata T; Miyasaka M, Contributor, Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressiong turmor cells.
    Matrix Biology Institute, 2005, Not refereed
    9780977135905
  • キーワードで理解する免疫学イラストマップ
    平田 多佳子, Contributor, 接着分子
    羊土社, 2004, Not refereed
    9784897065779
  • KEY WORD 1996-'97 炎症・免疫系
    平田 多佳子, Contributor, トロンボキサンA2受容体
    先端医学社, 1996, Not refereed
    491589231x
  • 血小板受容体
    平田 多佳子; 牛首 文隆; 平田 雅一; 成宮 周; 大熊 稔, Contributor, トロンボキサンA2受容体
    金芳堂, 1992, Not refereed
    9784765306744
■ Lectures, oral presentations, etc.
  • カニクイザルの腫瘍浸潤T細胞から腫瘍殺傷能を有するTCR遺伝子を単離する
    近藤 健太; 寺田 晃士; 石垣 宏仁; 里岡 大樹; 永野 誠治; 増田 喬子; 平田 多佳子; 小笠原 一誠; 伊藤 靖; 河本 宏; 縣 保年
    日本がん免疫学会総会プログラム・抄録集, Sep. 2020, 日本がん免疫学会
  • アレルギー アナフィラキシー、気道炎症/喘息およびその他(皮膚炎を除く) I型過敏症におけるIgD発現細胞の関与(Allergy-2: Anaphylaxis, airway inflammation/asthma and others (except dermtitis) Involvement of IgD-expressing cells in type I hypersensitivity)
    Todo Kagefumi; Asano Kyoko; Satooka Hiroki; Hirata Takako
    日本免疫学会総会・学術集会記録, Nov. 2019, (NPO)日本免疫学会
  • 関節リウマチ、シェーグレン症候群、その他の自己免疫疾患 制御性T細胞におけるレドックスを介したシグナル伝達は自己免疫の発生に関与している(Rheumatoid arthritis, Sjogren's syndrome and other autoimmune diseases Redox-mediated signaling in regulatory T cells is involved in the development of autoimmunity)
    Satooka Hiroki; Sato Tomomi; Nakamura Yuzuki; Todo Kagefumi; Hirata Takako
    日本免疫学会総会・学術集会記録, Nov. 2019, (NPO)日本免疫学会
  • B細胞発生、活性化、機能の調節 貪食細胞は脾臓の休眠B細胞の活性化により誘導される(Regulation of B cell development, activation, and function Phagocytic cells are induced by activation of resting splenic B cells)
    Asano Kyoko; Todo Kagefumi; Hirata Takako
    日本免疫学会総会・学術集会記録, Nov. 2019, (NPO)日本免疫学会
■ Research Themes
  • 原発性免疫不全症における免疫不全と自己免疫の合併機序
    基盤研究(C)
    滋賀医科大学
    01 Apr. 2022, 31 Mar. 2025
  • Control mechanisms of regulatory T cell homeostasis by ERM proteins
    Grant-in-Aid for Scientific Research (C)
    Shiga University of Medical Science
    01 Apr. 2019, 31 Mar. 2022
  • Molecular mechanisms and control of immune cell migration to skin and mucosa
    Grant-in-Aid for Scientific Research (C)
    Shiga University of Medical Science
    21 Oct. 2016, 31 Mar. 2019
  • Molecular mechanisms and control of immune cell migration to inflamed sites
    Grant-in-Aid for Scientific Research (C)
    Shiga University of Medical Science
    01 Apr. 2013, 31 Mar. 2016
  • Control of leukocyte migration to inflamed sites and its application to the treatment of refractory inflammatory diseases
    Grant-in-Aid for Scientific Research (C)
    2010, 2012
  • ERMタンパク質によるリンパ球の動態制御機構の解明
    特定領域研究
    京都大学
    2010, 2011
  • 制御性T細胞の腫瘍浸潤の制御による抗腫瘍免疫の強化
    特定領域研究
    2008, 2009
  • Stromal factors regulating tumor cell motility
    Grant-in-Aid for Scientific Research on Priority Areas
    Osaka University
    2005, 2009
  • Molecular mechanisms of lymphocyte migration to the skin and its regulation
    Grant-in-Aid for Scientific Research (C)
    Osaka University
    2007, 2008
  • Molecular basis of lymphocyte migration to the skin and mechanisms of acquisition of skin-migrating activity
    Grant-in-Aid for Scientific Research (C)
    Osaka University
    2005, 2006
  • Mechanisms regulating leukocyte rolling mediated by selectin ligand PSGL-1
    Grant-in-Aid for Scientific Research (C)
    Osaka University
    2003, 2004
  • Identification and funs tonal analysis of novel molecules that regulate tumor cell motility
    Grant-in-Aid for Scientific Research on Priority Areas
    Osaka University
    2000, 2004
  • 感染により誘発されるリンパ節高内皮細静脈の機能変換とその獲得免疫成立における意義
    特定領域研究
    大阪大学
    2003, 2003