1999
生化学会奨励賞

Endothelial RhoA is essential for embryonic and postnatal vascular development by regulating KLF2-Notch1 signaling.
Wondwossen Wale Tesega; Akio Shimizu; Taha Hussain; Fumiya Sawasaki; Lucia Sugawara; Shoma Matsumoto; Masatsugu Ema; Akira Sato; Hisakazu Ogita
Journal of biochemistry, 25 Apr. 2026

Preferential crosstalk between perifollicular capillary vessels and dermal papilla cells during hair cycling homeostasis.
Ying Zeng; Akinari Abe; Satsuki Takashima; Miyu Kono; Reina Kagiyama; Mariko Komabayashi-Suzuki; Mariko Moriyama; Hiroyuki Moriyama; Tadashi Okamoto; Hideya Ando; Masaki Tanaka; Masamitsu Ichihashi; Masatsugu Ema; Ken-Ichi Mizutani
Scientific reports, 01 Apr. 2026

Klf5 regulates the transition from apical radial glia to intermediate progenitor cells in the developing mammalian brain.
Takahiro Fuchigami; Yoshitaka Hayashi; Anri Kuroda; Zakiyyah Munirah Mohd Zaki; Nur Azrah Fazera Mohd Ariffin; Kenny Anak Daun; Naoko Morimura; Hiroaki Kitagawa; Takuya Azami; Shoji Tatsumoto; Yasuhiro Go; Kazuhiko Uchida; Satoru Takahashi; Kazuhiko Nakabayashi; Masatsugu Ema; Seiji Hitoshi
The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 Mar. 2026

Optimizing CRISPR precision in mouse embryos via microhomology-mediated end joining-dominant targeting.
Khanui Lkhagvadorj; Eiichi Okamura; Taito Taki; Hayate Suzuki; Akihiro Kuno; Yasushi Itoh; Seiya Mizuno; Knut Woltjen; Masatsugu Ema
Communications biology, 23 Mar. 2026

Reversible cystogenesis in juvenile primate ADPKD models: evidence from PKD1 heterozygous monkeys.
Shoma Matsumoto; Toshifumi Morimura; Kenichi Kobayashi; Keiichi Tsuji; Masataka Nakaya; Tomoyuki Tsukiyama; Ikuo Kawamoto; Takahiro Nakagawa; Etsuko Morishige; Koji Fukuda; Teppei Iwakiri; Kazuhiko Nozaki; Akihiro Kawauchi; Susumu Kageyama; Shinji Kume; Saori Nishio; Yasushi Itoh; Masatsugu Ema
Human molecular genetics, 23 Feb. 2026

Suppression of the neutrophil-derived S100A8/A9 complex ameliorates doxorubicin-induced cardiomyopathy in non-human primates.
Fumiya Sawasaki; Akira Sato; Akio Shimizu; Shoma Matsumoto; Ikuo Kawamoto; Mitsuru Murase; Iori Itagaki; Hideaki Tsuchiya; Hirohito Ishigaki; Naoko Ueda; Issa Toyoda; Yasushi Itoh; Daisuke Okuzaki; Masatsugu Ema; Hisakazu Ogita
Biochemical pharmacology, Jan. 2026

Optimized Lentiviral Vector Production Using Dual-Pseudotyping with VSV-G and Sendai Virus HN Glycoproteins for Enhanced Gene Delivery in Diverse Cell Types.
Bat-Erdene Jargalsaikhan; Masanaga Muto; Masatsugu Ema
Methods in molecular biology (Clifton, N.J.), 2026

Preparation of Lentiviral Vectors for the Generation of Transgenic Cynomolgus Monkeys.
Masanaga Muto; Masatsugu Ema
Methods in molecular biology (Clifton, N.J.), 2026

Highly efficient production of transgenic rats with long DNA insertions using piggyBac transposase mRNA and piezo-assisted microinjection.
Kohtaro Morita; Shunya Ihashi; Eiichi Okamura; Kazuya Goto; Toru Yoshihara; Arata Honda; Masatsugu Ema; Masahide Asano
PloS one, 2026

Menstrual cycles, lifespan, and anti-Müllerian hormone in cynomolgus monkeys.
Akie Takebayashi; Shunichiro Tsuji; Tadashi Sankai; Chizuru Iwatani; Hideaki Tsuchiya; Masatsugu Ema; Takashi Murakami
Experimental animals, 19 Dec. 2025

Structure and thickness of Glisson's capsule differ considerably on the liver surface in mammalian species.
Hiroki Uchida; Naoyuki Aihara; Toshifumi Morimura; Shoma Matsumoto; Daichi Hasegawa; Tomoko Ichiki; Eiichi Okamura; Masanaga Muto; Go Sugahara; Toshio Miki; Masatsugu Ema; Kenichi Watanabe; Junichi Kamiie; Kinji Asahina
Anatomical record (Hoboken, N.J. : 2007), Dec. 2025

Correction: Jargalsaikhan et al. The Era of Gene Therapy: The Advancement of Lentiviral Vectors and Their Pseudotyping. Viruses 2025, 17, 1036.
Bat-Erdene Jargalsaikhan; Masanaga Muto; Masatsugu Ema
Viruses, 18 Nov. 2025

Neuronal migration depends on blood flow in the adult mammalian brain.
Takashi Ogino; Akari Saito; Masato Sawada; Shoko Takemura; Yuzuki Hara; Kanami Yoshimura; Jiro Nagase; Honomi Kawase; Takamasa Sato; Hiroyuki Inada; Vicente Herranz-Pérez; Yoh-Suke Mukouyama; Masatsugu Ema; José Manuel García-Verdugo; Junichi Nabekura; Kazunobu Sawamoto
eLife, 28 Oct. 2025

Efficient generation of single copy transgenic mice using piggyBat transposase from the little brown bat Myotis lucifugus†.
Eiichi Okamura; Shoma Matsumoto; Hayate Suzuki; Yoko Tanimoto; Tra Thi Huong Dinh; Natsuki Mikami; Masanaga Muto; Tomoko Matsumoto; Fumihiro Sugiyama; Satoru Takahashi; Knut Woltjen; Seiya Mizuno; Masatsugu Ema
Biology of reproduction, 13 Oct. 2025

Establishment of human trophoblast stem cells from term smooth chorion.
Takako Hoshiyama; Masanaga Muto; Shoma Matsumoto; Eiichi Okamura; Bat-Erdene Jargalsaikhan; Takashi Murakami; Shunichiro Tsuji; Masatsugu Ema
Placenta, Sep. 2025

The Era of Gene Therapy: The Advancement of Lentiviral Vectors and Their Pseudotyping.
Bat-Erdene Jargalsaikhan; Masanaga Muto; Masatsugu Ema
Viruses, 24 Jul. 2025

Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice.
Chi Lieu Kim Nguyen; Yumeno Kuba; Hoai Thu Le; Hossam Hassan Shawki; Natsuki Mikami; Madoka Aoki; Nanako Yasuhara; Hayate Suzuki; Saori Mizuno-Iijima; Shinya Ayabe; Yuki Osawa; Tomoyuki Fujiyama; Tra Thi Huong Dinh; Miyuki Ishida; Yoko Daitoku; Yoko Tanimoto; Kazuya Murata; Woojin Kang; Masatsugu Ema; Yuji Hirao; Atsuo Ogura; Satoru Takahashi; Fumihiro Sugiyama; Seiya Mizuno
Cell death discovery, 20 Jan. 2025

The Dual-Pseudotyped Lentiviral Vector with VSV-G and Sendai Virus HN Enhances Infection Efficiency through the Synergistic Effect of the Envelope Proteins.
Bat-Erdene Jargalsaikhan; Masanaga Muto; Youngeun Been; Shoma Matsumoto; Eiichi Okamura; Tadanobu Takahashi; Yutaka Narimichi; Yuuki Kurebayashi; Hideyuki Takeuchi; Takashi Shinohara; Ryo Yamamoto; Masatsugu Ema
Viruses, 23 May 2024

Fructose overconsumption accelerates renal dysfunction with aberrant glomerular endothelial-mesangial cell interactions in db/db mice.
Hiroaki Tsuruta; Mako Yasuda-Yamahara; Mamoru Yoshibayashi; Shogo Kuwagata; Kosuke Yamahara; Yuki Tanaka-Sasaki; Masami Chin-Kanasaki; Shoma Matsumoto; Masatsugu Ema; Shinji Kume
Biochimica et biophysica acta. Molecular basis of disease, 13 Feb. 2024

Deletion of Exoc7, but not Exoc3, in male germ cells causes severe spermatogenesis failure with spermatocyte aggregation in mice.
Natsuki Mikami; Chi Lieu Kim Nguyen; Yuki Osawa; Kanako Kato; Miyuki Ishida; Yoko Tanimoto; Kento Morimoto; Kazuya Murata; Woojin Kang; Funihiro Sugiyama; Masatsugu Ema; Satoru Takahasi; Seiya Mizuno
Experimental animals, 07 Feb. 2024

Null mutation of exocyst complex component 3-like does not affect vascular development in mice
Satsuki Takashima; Eiichi Okamura; Yusuke Ichiyama; Kiyoto Nishi; Akio Shimizu; Chisato Watanabe; Masanaga Muto; Shoma Matsumoto; Setsuko Tsukiyama-Fujii; Tomoyuki Tsukiyama; Hisakazu Ogita; Eiichiro Nishi; Masahito Ohji; Fumihiro Sugiyama; Satoru Takahashi; Seiya Mizuno; Ken Ichi Mizutani; Masatsugu Ema
Experimental Animals, 2024

Highly efficient transgenic mouse production using piggyBac and its application to rapid phenotyping at the founder generation
Eiichi Okamura; Seiya Mizuno; Shoma Matsumoto; Kazuya Murata; Yoko Tanimoto; Dinh Thi Huong Tra; Hayate Suzuki; Woojin Kang; Tomoka Ema; Kento Morimoto; Kanako Kato; Tomoko Matsumoto; Nanami Masuyama; Yusuke Kijima; Toshifumi Morimura; Fumihiro Sugiyama; Satoru Takahashi; Eiji Mizutani; Knut Woltjen; Nozomu Yachie; Masatsugu Ema
10 Dec. 2023, URL

Generation of a familial hypercholesterolemia model in non-human primate
Akira Sato; Tomoyuki Tsukiyama; Masahiro Komeno; Chizuru Iwatani; Hideaki Tsuchiya; Ikuo Kawamoto; Mitsuru Murase; Takahiro Nakagawa; Iori Itagaki; Yasunari Seita; Shoma Matsumoto; Masataka Nakaya; Akio Shimizu; Atsushi Yamada; Masatsugu Ema; Hisakazu Ogita
Scientific Reports, Dec. 2023

Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis
Takahito Iga; Hiroshi Kobayashi; Dai Kusumoto; Tsukasa Sanosaka; Nobuyuki Fujita; Ikue Tai-Nagara; Tomofumi Ando; Tomoko Takahashi; Koichi Matsuo; Katsuto Hozumi; Kosei Ito; Masatsugu Ema; Takeshi Miyamoto; Morio Matsumoto; Masaya Nakamura; Hideyuki Okano; Shinsuke Shibata; Jun Kohyama; Kevin K. Kim; Keiyo Takubo; Yoshiaki Kubota
Nature Cell Biology, Oct. 2023

Flk1 Deficiency and Hypoxia Synergistically Promote Endothelial Dysfunction, Vascular Remodeling, and Pulmonary Hypertension
Tatsuya Akiyama; Taketaro Sadahiro; Yu Yamada; Ryo Fujita; Yuto Abe; Koji Nakano; Seiichiro Honda; Masatsugu Ema; Yoshiaki Kubota; Satoshi Sakai; Nobuyuki Hizawa; Masaki Ieda
Arteriosclerosis, Thrombosis, and Vascular Biology, 01 Sep. 2023

Three-dimensional visualization of neural networks inside bone by Osteo-DISCO protocol and alteration of bone remodeling by surgical nerve ablation.
Kurando Utagawa; Takaei Shin; Hironori Yamada; Hiroki Ochi; Satoko Sunamura; Aiko Unno; Chihiro Akazawa; Masatsugu Ema; Shu Takeda; Atsushi Okawa; Shingo Sato
Scientific reports, 22 Mar. 2023

Signal regulatory protein alpha is a conserved marker for mouse and rat spermatogonial stem cells.
Takehiro Miyazaki; Mito Kanatsu-Shinohara; Masatsugu Ema; Takashi Shinohara
Biology of reproduction, 16 Jan. 2023

Computational Model Exploring Characteristic Pattern Regulation in Periventricular Vessels.
Hisako Takigawa-Imamura; Saito Hirano; Chisato Watanabe; Chiaki Ohtaka-Maruyama; Masatsugu Ema; Ken-Ichi Mizutani
Life (Basel, Switzerland), 09 Dec. 2022

Possible testosterone redundancy for 5α-dihydrotestosterone in the masculinization of mouse external genitalia.
Yuko Ueda; Kentaro Suzuki; Mizuki Kajimoto; Kota Fujimoto; Mala Mahendroo; Masatsugu Ema; Gen Yamada; Isao Hara
Experimental animals, 10 Nov. 2022

Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex
Hidenori Tabata; Megumi Sasaki; Masakazu Agetsuma; Hitomi Sano; Yuki Hirota; Michio Miyajima; Kanehiro Hayashi; Takao Honda; Masashi Nishikawa; Yutaka Inaguma; Hidenori Ito; Hirohide Takebayashi; Masatsugu Ema; Kazuhiro Ikenaka; Junichi Nabekura; Koh-ichi Nagata; Kazunori Nakajima
Nature Communications, 02 Nov. 2022, Refereed

Essential Roles of Exocyst Complex Component 3-like 2 on Cardiovascular Development in Mice.
Chisato Watanabe; Hirotoshi Shibuya; Yusuke Ichiyama; Eiichi Okamura; Setsuko Tsukiyama-Fujii; Tomoyuki Tsukiyama; Shoma Matsumoto; Jun Matsushita; Takuya Azami; Yoshiaki Kubota; Masahito Ohji; Fumihiro Sugiyama; Satoru Takahashi; Seiya Mizuno; Masaru Tamura; Ken-Ichi Mizutani; Masatsugu Ema
Life (Basel, Switzerland), 28 Oct. 2022

Coupling of angiogenesis and odontogenesis orchestrates tooth mineralization in mice.
Tomoko Matsubara; Takahito Iga; Yuki Sugiura; Dai Kusumoto; Tsukasa Sanosaka; Ikue Tai-Nagara; Norihiko Takeda; Guo-Hua Fong; Kosei Ito; Masatsugu Ema; Hideyuki Okano; Jun Kohyama; Makoto Suematsu; Yoshiaki Kubota
The Journal of experimental medicine, 04 Apr. 2022

Early development of the pulmonary vascular system: An anatomical and histochemical reinvestigation of the pulmonary venous return development in mice.
Shizuka Abe; Aki Murashima; Eiji Kimura; Masatsugu Ema; Jiro Hitomi
Acta histochemica, Feb. 2022

KLF5-regulated extracellular matrix remodeling secures biliary epithelial tissue integrity against cholestatic liver injury
Minami Yamada; Hajime Okada; Masatsugu Ema; Yamato Kikkawa; Atsushi Miyajima; Tohru Itoh
28 Jan. 2022, URL

Intersection of regulatory pathways controlling hemostasis and hemochorial placentation.
Masanaga Muto; Damayanti Chakraborty; Kaela M Varberg; Ayelen Moreno-Irusta; Khursheed Iqbal; Regan L Scott; Ross P McNally; Ruhul H Choudhury; John D Aplin; Hiroaki Okae; Takahiro Arima; Shoma Matsumoto; Masatsugu Ema; Alan E Mast; Elin Grundberg; Michael J Soares
Proceedings of the National Academy of Sciences of the United States of America, 14 Dec. 2021

Genetic Deletion of Vascular Endothelial Growth Factor Receptor 2 in Endothelial Cells Leads to Immediate Disruption of Tumor Vessels and Aggravation of Hypoxia.
Yasuaki Kido; Tomofumi Ando; Takahito Iga; Masatsugu Ema; Yoshiaki Kubota; Ikue Tai-Nagara
The American journal of pathology, 30 Nov. 2021

The X chromosome dosage compensation program during the development of cynomolgus monkeys.
Ikuhiro Okamoto; Tomonori Nakamura; Kotaro Sasaki; Yukihiro Yabuta; Chizuru Iwatani; Hideaki Tsuchiya; Shin-Ichiro Nakamura; Masatsugu Ema; Takuya Yamamoto; Mitinori Saitou
Science (New York, N.Y.), 19 Nov. 2021

Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model.
Shinji Kumegawa; Gen Yamada; Daiki Hashimoto; Tsuyoshi Hirashima; Mizuki Kajimoto; Kyoichi Isono; Kota Fujimoto; Kentaro Suzuki; Kazuhisa Uemura; Masatsugu Ema; Shinichi Asamura
Biological procedures online, 11 Nov. 2021

A New Model for Specific Visualization of Skin Graft Neoangiogenesis Using Flt1-tdsRed BAC Transgenic Mice.
Mohamed Abdelhakim; Teruyuki Dohi; Mizuho Yamato; Hiroya Takada; Atsushi Sakai; Hidenori Suzuki; Masatsugu Ema; Shigetomo Fukuhara; Rei Ogawa
Plastic and reconstructive surgery, 01 Jul. 2021

Chromosomal-scale de novo genome assemblies of Cynomolgus Macaque and Common Marmoset.
Vasanthan Jayakumar; Osamu Nishimura; Mitsutaka Kadota; Naoki Hirose; Hiromi Sano; Yasuhiro Murakawa; Yumiko Yamamoto; Masataka Nakaya; Tomoyuki Tsukiyama; Yasunari Seita; Shinichiro Nakamura; Jun Kawai; Erika Sasaki; Masatsugu Ema; Shigehiro Kuraku; Hideya Kawaji; Yasubumi Sakakibara
Scientific data, 28 Jun. 2021

EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.
Yuki Osawa; Kazuya Murata; Miho Usui; Yumeno Kuba; Hoai Thu Le; Natsuki Mikami; Toshinori Nakagawa; Yoko Daitoku; Kanako Kato; Hossam Hassan Shawki; Yoshihisa Ikeda; Akihiro Kuno; Kento Morimoto; Yoko Tanimoto; Tra Thi Huong Dinh; Ken-Ichi Yagami; Masatsugu Ema; Shosei Yoshida; Satoru Takahashi; Seiya Mizuno; Fumihiro Sugiyama
eLife, 11 May 2021

Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway
Tra Thi Huong Dinh; Hiroyoshi Iseki; Seiya Mizuno; Saori Iijima-Mizuno; Yoko Tanimoto; Yoko Daitoku; Kanako Kato; Yuko Hamada; Ammar Shaker Hamed Hasan; Hayate Suzuki; Kazuya Murata; Masafumi Muratani; Masatsugu Ema; Jun-Dal Kim; Junji Ishida; Akiyoshi Fukamizu; Mitsuyasu Kato; Satoru Takahashi; Ken-ichi Yagami; Valerie Wilson; Ruth M Arkell; Fumihiro Sugiyama
eLife, 05 May 2021

Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor.
Keishi Otsu; Hiroko Ida-Yonemochi; Shojiro Ikezaki; Masatsugu Ema; Jiro Hitomi; Hayato Ohshima; Hidemitsu Harada
Development (Cambridge, England), 15 Feb. 2021

First Successful Delivery after Uterus Transplantation in MHC-Defined Cynomolgus Macaques.
Iori Kisu; Yojiro Kato; Yohei Masugi; Hirohito Ishigaki; Yohei Yamada; Kentaro Matsubara; Hideaki Obara; Katsura Emoto; Yusuke Matoba; Masataka Adachi; Kouji Banno; Yoko Saiki; Takako Sasamura; Iori Itagaki; Ikuo Kawamoto; Chizuru Iwatani; Takahiro Nakagawa; Mitsuru Murase; Hideaki Tsuchiya; Hiroyuki Urano; Masatsugu Ema; Kazumasa Ogasawara; Daisuke Aoki; Kenshi Nakagawa; Takashi Shiina
Journal of clinical medicine, 17 Nov. 2020

Clinical features of irreversible rejection after allogeneic uterus transplantation in cynomolgus macaques.
Iori Kisu; Katsura Emoto; Yohei Masugi; Yohei Yamada; Kentaro Matsubara; Hideaki Obara; Yusuke Matoba; Kouji Banno; Yojiro Kato; Yoko Saiki; Iori Itagaki; Ikuo Kawamoto; Chizuru Iwatani; Mitsuru Murase; Takahiro Nakagawa; Hideaki Tsuchiya; Hirohito Ishigaki; Hiroyuki Urano; Masatsugu Ema; Kazumasa Ogasawara; Daisuke Aoki; Kenshi Nakagawa; Takashi Shiina
Scientific reports, 17 Aug. 2020

Macrophages fine-tune pupil shape during development.
Moe Takahashi; Mika Misaki; Shinsuke Shibata; Takahito Iga; Tomoko Shindo; Ikue Tai-Nagara; Ayako Hirata; Marina Ogawa; Takeshi Miyamoto; Taneaki Nakagawa; Masatsugu Ema; Yusuke Ichiyama; David T Shima; Katsuto Hozumi; Satoshi Nishimura; Yoshiaki Kubota
Developmental biology, 15 Aug. 2020, Refereed, Not invited

Simultaneous fluorescence imaging of distinct nerve and blood vessel patterns in dual Thy1-YFP and Flt1-DsRed transgenic mice.
Samuel M Santosa; Kai Guo; Michael Yamakawa; Evguenia Ivakhnitskaia; Neeraj Chawla; Tara Nguyen; Kyu-Yeon Han; Masatsugu Ema; Mark I Rosenblatt; Jin-Hong Chang; Dimitri T Azar
Angiogenesis, Aug. 2020, Refereed, Not invited

Organogenesis and distribution of the ocular lymphatic vessels in the anterior eye.
Yifan Wu; Young Jin Seong; Kin Li; Dongwon Choi; Eunkyung Park; George H Daghlian; Eunson Jung; Khoa Bui; Luping Zhao; Shrimika Madhavan; Saren Daghlian; Patill Daghlian; Desmond Chin; Il-Taeg Cho; Alex K Wong; Martin Heur; Sandy Zhang-Nunes; James C Tan; Masatsugu Ema; Tina T Wong; Alex S Huang; Young-Kwon Hong
JCI insight, 09 Jul. 2020, Refereed, Not invited

EXOC1 regulates cell morphology of spermatogonia and spermatocytes in mice
Yuki Osawa; Miho Usui; Yumeno Kuba; Hoai Thu Le; Natsuki Mikami; Toshinori Nakagawa; Yoko Daitoku; Kanako Kato; Hossam Hassan Shawki; Yoshihisa Ikeda; Akihiro Kuno; Kento Morimoto; Yoko Tanimoto; Tra Thi Huong Dinh; Kazuya Murata; Ken-ichi Yagami; Masatsugu Ema; Shosei Yoshida; Satoru Takahashi; Seiya Mizuno; Fumihiro Sugiyama
07 Jun. 2020, URL

Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts.
Shoma Matsumoto; Christopher J Porter; Naomi Ogasawara; Chizuru Iwatani; Hideaki Tsuchiya; Yasunari Seita; Yu-Wei Chang; Ikuhiro Okamoto; Mitinori Saitou; Masatsugu Ema; Theodore J Perkins; William L Stanford; Satoshi Tanaka
Scientific reports, 22 Apr. 2020, Refereed, Not invited

Neuron-derived VEGF contributes to cortical and hippocampal development independently of VEGFR1/2-mediated neurotrophism.
Keisuke Okabe; Hugh Fukada; Ikue Tai-Nagara; Tomofumi Ando; Takao Honda; Kazunori Nakajima; Norihiko Takeda; Guo-Hua Fong; Masatsugu Ema; Yoshiaki Kubota
Developmental biology, 15 Mar. 2020, Refereed, Not invited

Aging of the Vascular System and Neural Diseases.
Chisato Watanabe; Tsutomu Imaizumi; Hiromi Kawai; Kazuma Suda; Yoichi Honma; Masamitsu Ichihashi; Masatsugu Ema; Ken-Ichi Mizutani
Frontiers in aging neuroscience, 2020

Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein.
Yasunari Seita; Toshifumi Morimura; Naoki Watanabe; Chizuru Iwatani; Hideaki Tsuchiya; Shinichiro Nakamura; Toshiharu Suzuki; Daijiro Yanagisawa; Tomoyuki Tsukiyama; Masataka Nakaya; Eiichi Okamura; Masanaga Muto; Masatsugu Ema; Masaki Nishimura; Ikuo Tooyama
Journal of Alzheimer's disease : JAD, 2020, Refereed, Not invited

Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease.
Tomoyuki Tsukiyama; Kenichi Kobayashi; Masataka Nakaya; Chizuru Iwatani; Yasunari Seita; Hideaki Tsuchiya; Jun Matsushita; Kahoru Kitajima; Ikuo Kawamoto; Takahiro Nakagawa; Koji Fukuda; Teppei Iwakiri; Hiroyuki Izumi; Iori Itagaki; Shinji Kume; Hiroshi Maegawa; Ryuichi Nishinakamura; Saori Nishio; Shinichiro Nakamura; Akihiro Kawauchi; Masatsugu Ema
Nature communications, 11 Dec. 2019, Refereed, Not invited

Induction of the Germ-Cell Fate from Pluripotent Stem Cells in Cynomolgus Monkeys.
Sakai Y; Nakamura T; Okamoto I; Gyobu-Motani S; Ohta H; Yabuta Y; Tsukiyama T; Iwatani C; Tsuchiya H; Ema M; Morizane A; Takahashi J; Yamamoto T; Saitou M
Biology of reproduction, Nov. 2019, Refereed, Not invited

Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development.
Mariko Komabayashi-Suzuki; Emiko Yamanishi; Chisato Watanabe; Megumi Okamura; Hidenori Tabata; Ryota Iwai; Itsuki Ajioka; Jun Matsushita; Hiroyasu Kidoya; Nobuyuki Takakura; Tadashi Okamoto; Kazuo Kinoshita; Masamitsu Ichihashi; Koh-Ichi Nagata; Masatsugu Ema; Ken-Ichi Mizutani
Cell reports, 29 Oct. 2019, Refereed, Not invited

Long-Term Outcome and Rejection After Allogeneic Uterus Transplantation in Cynomolgus Macaques.
Iori Kisu; Hirohito Ishigaki; Katsura Emoto; Yojiro Kato; Yohei Yamada; Kentaro Matsubara; Hideaki Obara; Yohei Masugi; Yusuke Matoba; Masataka Adachi; Kouji Banno; Yoko Saiki; Iori Itagaki; Ikuo Kawamoto; Chizuru Iwatani; Takahiro Nakagawa; Hideaki Tsuchiya; Takako Sasamura; Hiroyuki Urano; Masatsugu Ema; Kazumasa Ogasawara; Daisuke Aoki; Kenshi Nakagawa; Takashi Shiina
Journal of clinical medicine, 01 Oct. 2019, Refereed, Not invited

Interaction of the nervous system and vascular system is required for the proper assembly of the neocortex.
Satsuki Takashima; Chisato Watanabe; Masatsugu Ema; Ken-Ichi Mizutani
Neurochemistry international, Oct. 2019, Refereed, Not invited

Hereditary kidney disease modeling in cynomolgus monkeys using genome editing
NAKAYA Masataka; NAKAGAWA Takahiro; FUKUDA Koji; IWAKIRI Teppei; IZUMI Hiroyuki; ITAGAKI Iori; NAKAMURA Shinichiro; KAWAUCHI Akihiro; EMA Masatsugu; TSUKIYAMA Tomoyuki; KOBAYASHI Kenichi; IWATANI Chizuru; TSUCHIYA Hideaki; SEITA Yasunari; MATSUSHITA Jun; KITAJIMA Kahoru; KAWAMOTO Ikuo
The Journal of Reproduction and Development Supplement, Sep. 2019

Hepatocyte Elovl6 determines ceramide acyl-chain length and hepatic insulin sensitivity in mice.
Matsuzaka T; Kuba M; Koyasu S; Yamamoto Y; Motomura K; Arulmozhiraja S; Ohno H; Sharma R; Shimura T; Okajima Y; Han SI; Aita Y; Mizunoe Y; Osaki Y; Iwasaki H; Yatoh S; Suzuki H; Sone H; Takeuchi Y; Yahagi N; Miyamoto T; Sekiya M; Nakagawa Y; Ema M; Takahashi S; Tokiwa H; Shimano H
Hepatology (Baltimore, Md.), Sep. 2019, Refereed, Not invited

Quantification of angiogenesis and lymphangiogenesis in the dual ex vivo aortic and thoracic duct assay.
Wang S; Yamakawa M; Santosa SM; Chawla N; Guo K; Montana M; Hallak JA; Han KY; Ema M; Rosenblatt MI; Chang JH; Azar DT
Protein and peptide letters, Sep. 2019, Refereed, Not invited

Cables2 Is a Novel Smad2-Regulatory Factor Essential for Early Embryonic Development in Mice
Tra Thi Huong Dinh; Hiroyoshi Iseki; Seiya Mizuno; Saori Iijima-Mizuno; Yoko Tanimoto; Yoko Daitoku; Kanako Kato; Yuko Hamada; Ammar Shaker; Hamed Hasan; Hayate Suzuki; Kazuya Murata; Masafumi Muratani; Masatsugu Ema; Jun-Dal Kim; Junji Ishida; Akiyoshi Fukamizu; Mitsuyasu Kato; Satoru Takahashi; Ken-ichi Yagami; Valerie Wilson; Ruth M Arkell; Fumihiro Sugiyama
Aug. 2019, Refereed, Not invited, URL

Highly efficient induction of primate iPS cells by combining RNA transfection and chemical compounds.
Watanabe T; Yamazaki S; Yoneda N; Shinohara H; Tomioka I; Higuchi Y; Yagoto M; Ema M; Suemizu H; Kawai K; Sasaki E
Genes to cells : devoted to molecular & cellular mechanisms, Jul. 2019, Refereed, Not invited

Regulation of the ERK signalling pathway in the developing mouse blastocyst.
Azami T; Bassalert C; Allègre N; Valverde Estrella L; Pouchin P; Ema M; Chazaud C
Development (Cambridge, England), Jul. 2019, Refereed, Not invited

Poor second ovarian stimulation in cynomolgus monkeys (Macaca fascicularis) is associated with the production of antibodies against human follicle-stimulating hormone.
Yasunari Seita; Chizuru Iwatani; Hideaki Tsuchiya; Shinichiro Nakamura; Fuminori Kimura; Takashi Murakami; Masatsugu Ema
The Journal of reproduction and development, 14 Jun. 2019, Refereed, Not invited

Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†.
Seita Y; Tsukiyama T; Azami T; Kobayashi K; Iwatani C; Tsuchiya H; Nakaya M; Tanabe H; Hitoshi S; Miyoshi H; Nakamura S; Kawauchi A; Ema M
Biology of reproduction, Jun. 2019, Refereed, Not invited

Generation of bicistronic reporter knockin mice for visualizing germ layers.
Suzuki H; Dinh TTH; Daitoku Y; Tanimoto Y; Kato K; Azami T; Ema M; Murata K; Mizuno S; Sugiyama F
Experimental animals, Jun. 2019, Refereed, Not invited

Generation of an OCT3/4 reporter cynomolgus monkey ES cell line using CRISPR/Cas9.
Kobayashi K; Tsukiyama T; Nakaya M; Kageyama S; Tomita K; Murai R; Yoshida T; Narita M; Kawauchi A; Ema M
Stem cell research, May 2019, Refereed, Not invited

The dynamics of revascularization after white matter infarction monitored in Flt1-tdsRed and Flk1-GFP mice.
Hiroya Shimauchi-Ohtaki; Masashi Kurachi; Masae Naruse; Koji Shibasaki; Shouta Sugio; Ken Matsumoto; Masatsugu Ema; Yuhei Yoshimoto; Yasuki Ishizaki
Neuroscience letters, 23 Jan. 2019, Not refereed, Not invited

Primate DNA/RNA database; development and application for medicine
KAWAI Jun; NAKAYA Masataka; SASAKI Erika; INOUE Takashi; WATANABE Toshiaki; SAKAKIBARA Yasubumi; JAYAKUMAR Vasanthan; NAITO Yuki; MURAKAWA Yasuhiro; KAWAJI Hideya; HIROSE Naoki; SANO Hiromi; OKAZAKI Yasushi; YAGI Ken; YAMAMOTO Yumiko; EMA Masatsugu; SEITA Yasunari; TSUKIYAMA Tomoyuki
Annual Meeting of the Japanese Society of Toxicology, 2019

Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells.
Watanabe C; Matsushita J; Azami T; Tsukiyama-Fujii S; Tsukiyama T; Mizuno S; Takahashi S; Ema M
PloS one, 2019, Refereed, Not invited

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche.
Kitadate Y; Jörg DJ; Tokue M; Maruyama A; Ichikawa R; Tsuchiya S; Segi-Nishida E; Nakagawa T; Uchida A; Kimura-Yoshida C; Mizuno S; Sugiyama F; Azami T; Ema M; Noda C; Kobayashi S; Matsuo I; Kanai Y; Nagasawa T; Sugimoto Y; Takahashi S; Simons BD; Yoshida S
Cell stem cell, Jan. 2019, Refereed, Not invited

Fluorescent reporter transgenic mice for in vivo live imaging of angiogenesis and lymphangiogenesis
Susan J. Doh; Michael Yamakawa; Samuel M. Santosa; Mario Montana; Kai Guo; Joseph R. Sauer; Nicholas Curran; Kyu Yeon Han; Charles Yu; Masatsugu Ema; Mark I. Rosenblatt; Jin Hong Chang; Dimitri T. Azar
Angiogenesis, 01 Nov. 2018, Not refereed, Not invited

Klf5 suppresses ERK signaling in mouse pluripotent stem cells
Takuya Azami; Ken Matsumoto; Hyojung Jeon; Tsuyoshi Waku; Masafumi Muratani; Hitoshi Niwa; Satoru Takahashi; Satoru Takahashi; Satoru Takahashi; Satoru Takahashi; Satoru Takahashi; Masatsugu Ema; Masatsugu Ema
PloS one, Nov. 2018, Not refereed, Not invited

Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system
Katia Herz; Alexandra Becker; Chenyue Shi; Masatsugo Ema; Satoru Takahashi; Michael Potente; Michael Hesse; Bernd K. Fleischmann; Daniela Wenzel
Angiogenesis, 01 May 2018, Not refereed, Not invited, URL

Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells
So Goto; So Goto; Akishi Onishi; Akishi Onishi; Kazuyo Misaki; Shigenobu Yonemura; Sunao Sugita; Sunao Sugita; Hiromi Ito; Yoko Ohigashi; Masatsugu Ema; Hirokazu Sakaguchi; Kohji Nishida; Masayo Takahashi; Masayo Takahashi
eLife, 03 Apr. 2018, Not refereed, Not invited

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury
Hajime Okada; Minami Yamada; Kenji Kamimoto; Cindy Yuet-Yin Kok; Kota Kaneko; Masatsugu Ema; Atsushi Miyajima; Tohru Itoh
Journal of Biological Chemistry, 2018, Not refereed, Not invited

Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction
Shota Kurotsu; Rina Osakabe; Mari Isomi; Fumiya Tamura; Taketaro Sadahiro; Naoto Muraoka; Hidenori Kojima; Sho Haginiwa; Hidenori Tani; Kaori Nara; Yoshiaki Kubota; Masatsugu Ema; Keiichi Fukuda; Takeshi Suzuki; Masaki Ieda
Biochemical and Biophysical Research Communications, 01 Jan. 2018, Not refereed, Not invited

Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis
Wei Zhong; Xinbo Gao; Shuangyong Wang; Kyuyeon Han; Masatsugu Ema; Susanne Adams; Ralf H. Adams; Mark I. Rosenblatt; Jin-Hong Chang; Dimitri T. Azar
ANGIOGENESIS, Nov. 2017, Not refereed, Not invited

Klf5 maintains the balance of primitive endoderm to epiblast specification during mouse embryonic development by suppression of Fgf4
Azami, Takuya; Waku, Tsuyoshi; Matsumoto, Ken; Jeon, Hyojung; Muratani, Masafumi; Kawashima, Akihiro; Yanagisawa, Jun; Manabe, Ichiro; Nagai, Ryozo; Kunath, Tilo; Nakamura, Tomonori; Kurimoto, Kazuki; Saitou, Mitinori; Takahashi, Satoru; Ema, Masatsugu
Development (Cambridge, England), Oct. 2017, Refereed, Not invited, URL

Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4
Takuya Azami; Tsuyoshi Waku; Ken Matsumoto; Hyojung Jeon; Masafumi Muratani; Akihiro Kawashima; Jun Yanagisawa; Ichiro Manabe; Ryozo Nagai; Tilo Kunath; Tomonori Nakamura; Kazuki Kurimoto; Mitinori Saitou; Satoru Takahashi; Masatsugu Ema
DEVELOPMENT, Oct. 2017, Not refereed, Not invited

Fluorescence and Bioluminescence Imaging of Angiogenesis in Flk1-Nano-lantern Transgenic Mice.
Jun Matsushita; Shigenori Inagaki; Tomomi Nishie; Tomoki Sakasai; Junko Tanaka; Chisato Watanabe; Ken-Ichi Mizutani; Yoshihiro Miwa; Ken Matsumoto; Kazuhiro Takara; Hisamichi Naito; Hiroyasu Kidoya; Nobuyuki Takakura; Takeharu Nagai; Satoru Takahashi; Masatsugu Ema
Scientific reports, 20 Apr. 2017, Refereed, Not invited

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-beta Signaling in Developing Skin Vasculature
Tomoko Yamazaki; Ani Nalbandian; Yutaka Uchida; Wenling Li; Thomas D. Arnold; Yoshiaki Kubota; Seiji Yamamoto; Masatsugu Ema; Yoh-suke Mukouyama
CELL REPORTS, Mar. 2017, Not refereed, Not invited

Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown
Shuntaro Ogura; Kaori Kurata; Yuki Hattori; Hiroshi Takase; Toshina Ishiguro-Oonuma; Yoonha Hwang; Soyeon Ahn; Inwon Park; Wataru Ikeda; Sentaro Kusuhara; Yoko Fukushima; Hiromi Nara; Hideto Sakai; Takashi Fujiwara; Jun Matsushita; Masatsugu Ema; Masanori Hirashima; Takashi Minami; Masabumi Shibuya; Nobuyuki Takakura; Pilhan Kim; Takaki Miyata; Yuichiro Ogura; Akiyoshi Uemura
JCI insight, Feb. 2017, Refereed, Not invited

全身でGFPを発現するトランスジェニックカニクイザルの作製
清田 弥寿成; 築山 智之; 岩谷 千鶴; 松下 淳; 土屋 英明; 佐々木 えりか; 依馬 正次
The Journal of Reproduction and Development, Sep. 2016

心血管系を生み出す幹・前駆細胞の多様性、微小環境と疾患 大脳皮質発生過程における神経と血管の相互依存性
水谷 健一; 山西 恵美子; 鈴木 真理子; 渡部 千里; 岩井 亮太; 依馬 正次
日本生化学会大会プログラム・講演要旨集, Sep. 2016

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells
Le Tran Phuc Khoa; Takuya Azami; Tomoyuki Tsukiyama; Jun Matsushita; Setsuko Tsukiyama-Fujii; Satoru Takahashi; Masatsugu Ema
PLOS ONE, Jul. 2016, Not refereed, Not invited

Developmental regression of hyaloid vasculature is triggered by neurons
Yusuke Yoshikawa; Toru Yamada; Ikue Tai-Nagara; Keisuke Okabe; Yuko Kitagawa; Masatsugu Ema; Yoshiaki Kubota
JOURNAL OF EXPERIMENTAL MEDICINE, Jun. 2016, Not refereed, Not invited

Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body
Yasunari Seita; Tomoyuki Tsukiyama; Chizuru Iwatani; Hideaki Tsuchiya; Jun Matsushita; Takuya Azami; Junko Okahara; Shinichiro Nakamura; Yoshitaka Hayashi; Seiji Hitoshi; Yasushi Itoh; Takeshi Imamura; Masaki Nishimura; Ikuo Tooyama; Hiroyuki Miyoshi; Mitinori Saitou; Kazumasa Ogasawara; Erika Sasaki; Masatsugu Ema
SCIENTIFIC REPORTS, Apr. 2016, Not refereed, Not invited

Comprehensive Identification of Kruppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming
Hyojung Jeon; Tsuyoshi Waku; Takuya Azami; Le Tran Phuc Khoa; Jun Yanagisawa; Satoru Takahashi; Masatsugu Ema
PLOS ONE, Mar. 2016, Not refereed, Not invited

Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus
Koichi Matsuo; Yukiko Kuroda; Nobuhito Nango; Kouji Shimoda; Yoshiaki Kubota; Masatsugu Ema; Latifa Bakiri; Erwin F. Wagner; Yoshihiro Takeda; Wataru Yashiro; Atsushi Momose
DEVELOPMENT, Nov. 2015, Not refereed, Not invited

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial beta 1 integrin recycling
Tsunaki Hongu; Yuji Funakoshi; Shigetomo Fukuhara; Teruhiko Suzuki; Susumu Sakimoto; Nobuyuki Takakura; Masatsugu Ema; Satoru Takahashi; Susumu Itoh; Mitsuyasu Kato; Hiroshi Hasegawa; Naoki Mochizuki; Yasunori Kanaho
NATURE COMMUNICATIONS, Aug. 2015, Not refereed, Not invited

Forced Expression of Nanog or Esrrb Preserves the ESC Status in the Absence of Nucleostemin Expression
Miyuki Katano; Masatsugu Ema; Yutaka Nakachi; Yosuke Mizuno; Masataka Hirasaki; Ayumu Suzuki; Atsushi Ueda; Masazumi Nishimoto; Satoru Takahashi; Yasushi Okazaki; Akihiko Okuda
STEM CELLS, Apr. 2015, Not refereed, Not invited

Functional Compensation Between Myc and PI3K Signaling Supports Self- Renewal of Embryonic Stem Cells
Tomoaki Hishida; Yutaka Nakachi; Yosuke Mizuno; Miyuki Katano; Yasushi Okazaki; Masatsugu Ema; Satoru Takahashi; Masataka Hirasaki; Ayumu Suzuki; Atsushi Ueda; Masazumi Nishimoto; Yuriko Hishida-Nozaki; Eric Vazquez-Ferrer; Ignacio Sancho-Martinez; Juan Carlos Izpisua Belmonte; Akihiko Okuda
STEM CELLS, Mar. 2015, Not refereed, Not invited

Combined Administration of BMP-2 and HGF Facilitate Bone Regeneration through Angiogenic Mechanisms
Tomoyuki Masuda; Keishi Otsu; Mika Kumakami-Sakano; Naoki Fujiwara; Masatsugu Ema; Jiro Hitomi; Yoshiki Sugiyama; Hidemitsu Harada
JOURNAL OF HARD TISSUE BIOLOGY, Jan. 2015, Refereed, Not invited

Neurons Limit Angiogenesis by Titrating VEGF in Retina
Keisuke Okabe; Sakiko Kobayashi; Toru Yamada; Toshihide Kurihara; Ikue Tai-Nagara; Takeshi Miyamoto; Yoh-suke Mukouyama; Thomas N. Sato; Toshio Suda; Masatsugu Ema; Yoshiaki Kubota
CELL, Oct. 2014, Not refereed, Not invited

Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow
Shugo Kowata; Sumio Isogai; Kazunori Murai; Shigeki Ito; Koujiro Tohyama; Masatsugu Ema; Jiro Hitomi; Yoji Ishida
THROMBOSIS AND HAEMOSTASIS, Oct. 2014, Refereed, Not invited

Roles of VEGF-A signalling in development, regeneration, and tumours
Ken Matsumoto; Masatsugu Ema
JOURNAL OF BIOCHEMISTRY, Jul. 2014, Refereed, Not invited

Generation and Characterization of Ins1-cre-driver C57BL/6N for Exclusive Pancreatic Beta Cell-specific Cre-loxP Recombination
Yoshikazu Hasegawa; Yoko Daitoku; Seiya Mizuno; Yoko Tanimoto; Saori Mizuno-Iijima; Miki Matsuo; Noriko Kajiwara; Masatsugu Ema; Hisashi Oishi; Yoshihiro Miwa; Kazuyuki Mekada; Atsushi Yoshiki; Satoru Takahashi; Fumihiro Sugiyama; Ken-ichi Yagami
EXPERIMENTAL ANIMALS, Apr. 2014, Refereed, Not invited

Study of normal and pathological blood vessel morphogenesis in Flk1-GFP and Flt1-tdsRed BAC Tg mice
Matsumoto,Ken; Kubota,Yoshiaki; Takahashi,Saoru; Ema,Masatsugu
ANGIOGENESIS, Jan. 2014, Refereed, Not invited

Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination
Yoshikazu Hasegawa; Yoko Daitoku; Keito Sekiguchi; Yoko Tanimoto; Saori Mizuno-Iijima; Seiya Mizuno; Noriko Kajiwara; Masatsugu Ema; Yoshihiro Miwa; Kazuyuki Mekada; Atsushi Yoshiki; Satoru Takahashi; Fumihiro Sugiyama; Ken-Ichi Yagami
Experimental Animals, 31 Oct. 2013, Refereed, Not invited

C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes
Takashi Kudo; Takashi Sato; Kozue Hagiwara; Yukinori Kozuma; Takashi Yamaguchi; Yuzuru Ikehara; Michito Hamada; Ken Matsumoto; Masatsugu Ema; Soichiro Murata; Nobuhiro Ohkohchi; Hisashi Narimatsu; Satoru Takahashi
BLOOD, Aug. 2013, Refereed, Not invited

In Vivo Function and Evolution of the Eutherian-Specific Pluripotency Marker UTF1
Masazumi Nishimoto; Miyuki Katano; Toshiyuki Yamagishi; Tomoaki Hishida; Masayoshi Kamon; Ayumu Suzuki; Masataka Hirasaki; Yoko Nabeshima; Yo-ichi Nabeshima; Yukako Katsura; Yoko Satta; Janine E. Deakin; Jennifer A. Marshall Graves; Yoko Kuroki; Ryuichi Ono; Fumitoshi Ishino; Masatsugu Ema; Satoru Takahashi; Hidemasa Kato; Akihiko Okuda
PLOS ONE, Jul. 2013, Refereed, Not invited

Klf9 is necessary and sufficient for Purkinje cell survival in organotypic culture
C. Lebrun; H. X. Avci; R. Wehrle; M. Doulazmi; F. Jaudon; M. P. Morel; I. Rivals; M. Ema; S. Schmidt; C. Sotelo; G. Vodjdani; I. Dusart
MOLECULAR AND CELLULAR NEUROSCIENCE, May 2013, Refereed, Not invited

In vivo monitoring of pancreatic b-cell mass and intrahepatic insulin gene activity in Ins1-luc BAC transgenic mice by bioluminescence imaging.
Katsumata,Tokio; Oishi,Hisashi; Sekiguchi,Yukari; Nagasaki,Haruka; Daassi,Dhouha; Tai,Pei-Han; Ema,Masatsugu; Kudo,Takashi; Takahashi,Satoru
PLoS One, Apr. 2013, Refereed, Not invited

Bioluminescence Imaging of beta Cells and Intrahepatic Insulin Gene Activity under Normal and Pathological Conditions
Tokio Katsumata; Hisashi Oishi; Yukari Sekiguchi; Haruka Nagasaki; Dhouha Daassi; Pei-Han Tai; Masatsugu Ema; Takashi Kudo; Satoru Takahashi
PLOS ONE, Apr. 2013, Refereed, Not invited

Generation of Naive-Like Porcine-Induced Pluripotent Stem Cells Capable of Contributing to Embryonic and Fetal Development
Shuh-hei Fujishiro; Kazuaki Nakano; Yoshihisa Mizukami; Takuya Azami; Yoshikazu Arai; Hitomi Matsunari; Rikiya Ishino; Takashi Nishimura; Masahito Watanabe; Tomoyuki Abe; Yutaka Furukawa; Kazuhiro Umeyama; Shinya Yamanaka; Masatsugu Ema; Hiroshi Nagashima; Yutaka Hanazono
STEM CELLS AND DEVELOPMENT, Feb. 2013, Refereed, Not invited

Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice
Hisashi Oishi; Susumu Itoh; Ken Matsumoto; Hiroyuki Ishitobi; Rumiko Suzuki; Masatsugu Ema; Takahiro Kojima; Kazuhiko Uchida; Mitsuyasu Kato; Toshio Miyata; Satoru Takahashi
JOURNAL OF BIOCHEMISTRY, Dec. 2012, Refereed, Not invited

Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha 1 and kruppel-like factor 9 in Purkinje cells
Hasan X. Avci; Clement Lebrun; Rosine Wehrle; Mohamed Doulazmi; Fabrice Chatonnet; Marie-Pierre Morel; Masatsugu Ema; Guilan Vodjdani; Constantino Sotelo; Frederic Flamant; Isabelle Dusart
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Aug. 2012, Refereed, Not invited

Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice
Ken Matsumoto; Takuya Azami; Ayaka Otsu; Haruka Takase; Hiroyuki Ishitobi; Junko Tanaka; Yoshihiro Miwa; Satoru Takahashi; Masatsugu Ema
GENESIS, Jul. 2012, Refereed, Not invited

Genome-wide identification of endothelial cell-enriched genes in the mouse embryo
Haruka Takase; Ken Matsumoto; Rie Yamadera; Yoshiaki Kubota; Ayaka Otsu; Rumiko Suzuki; Hiroyuki Ishitobi; Hiromi Mochizuki; Takahiro Kojima; Shingo Takano; Kazuhiko Uchida; Satoru Takahashi; Masatsugu Ema
BLOOD, Jul. 2012, Refereed, Not invited

Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice
Keigo Sano; Osamu Katsuta; Satoshi Shirae; Yoshiaki Kubota; Masatsugu Ema; Toshio Suda; Masatsugu Nakamura; Masanori Hirashima
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2012, Refereed, Not invited

Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse
Hiroyuki Ishitobi; Asami Wakamatsu; Fang Liu; Takuya Azami; Michito Hamada; Ken Matsumoto; Hiroshi Kataoka; Makoto Kobayashi; Kyunghee Choi; Shin-ichi Nishikawa; Satoru Takahashi; Masatsugu Ema
DEVELOPMENT, Dec. 2011, Refereed, Not invited

Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7 alpha (Fbw7 alpha) Causes Hepatosteatosis through Kruppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor gamma 2 (PPAR gamma 2) Pathway but Not SREBP-1c Protein in Mice
Shin Kumadaki; Tadayoshi Karasawa; Takashi Matsuzaka; Masatsugu Ema; Yoshimi Nakagawa; Masanori Nakakuki; Ryo Saito; Naoya Yahagi; Hitoshi Iwasaki; Hirohito Sone; Kazuhiro Takekoshi; Shigeru Yatoh; Kazuto Kobayashi; Akimitsu Takahashi; Hiroaki Suzuki; Satoru Takahashi; Nobuhiro Yamada; Hitoshi Shimano
JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2011, Refereed, Not invited

The E3 Ubiquitin Ligase Activity of Trip12 Is Essential for Mouse Embryogenesis
Masashi Kajiro; Mai Tsuchiya; Yoh-ichi Kawabe; Ryohei Furumai; Naoya Iwasaki; Yuki Hayashi; Miyuki Katano; Yuka Nakajima; Natsuka Goto; Tatsuya Watanabe; Akiko Murayama; Hisashi Oishi; Masatsugu Ema; Satoru Takahashi; Hiroyuki Kishimoto; Junn Yanagisawa
PLOS ONE, Oct. 2011, Refereed, Not invited

Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms
Tomoaki Hishida; Yuriko Nozaki; Yutaka Nakachi; Yosuke Mizuno; Yasushi Okazaki; Masatsugu Ema; Satoru Takahashi; Masazumi Nishimoto; Akihiko Okuda
CELL STEM CELL, Jul. 2011, Refereed, Not invited

Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero
Yoshiaki Kubota; Keiyo Takubo; Masanori Hirashima; Narihito Nagoshi; Kazuo Kishi; Yuji Okuno; Ayako Nakamura-Ishizu; Keigo Sano; Masato Murakami; Masatsugu Ema; Yoshiki Omatsu; Satoru Takahashi; Takashi Nagasawa; Masabumi Shibuya; Hideyuki Okano; Toshio Suda
JOURNAL OF EXPERIMENTAL MEDICINE, May 2011, Refereed, Not invited

RNA content in the nucleolus alters p53 acetylation via MYBBP1A
Takao Kuroda; Akiko Murayama; Naohiro Katagiri; Yu-mi Ohta; Etsuko Fujita; Hiroshi Masumoto; Masatsugu Ema; Satoru Takahashi; Keiji Kimura; Junn Yanagisawa
EMBO JOURNAL, Mar. 2011, Refereed, Not invited

Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 Is Necessary for Normal Endochondral Ossification and Aggrecan Metabolism
Takashi Sato; Takashi Kudo; Yuzuru Ikehara; Hiroyasu Ogawa; Tomoko Hirano; Katsue Kiyohara; Kozue Hagiwara; Akira Togayachi; Masatsugu Ema; Satoru Takahashi; Koji Kimata; Hideto Watanabe; Hisashi Narimatsu
JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2011, Refereed, Not invited

コンドロイチン硫酸は正常な軟骨内骨化に必要である(Chondroitin sulfate is essential for normal endochondral ossification)
佐藤 隆; 工藤 崇; 池原 譲; 小川 寛恭; 平野 朋子; 清原 克恵; 萩原 梢; 栂谷内 晶; 依馬 正次; 高橋 智; 木全 弘治; 渡辺 秀人; 成松 久
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010

Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice
Mayank Verma; Yoko Asakura; Hiroyuki Hirai; Shuichi Watanabe; Christopher Tastad; Guo-Hua Fong; Masatsugu Ema; Jarrod A. Call; Dawn A. Lowe; Atsushi Asakura
HUMAN MOLECULAR GENETICS, Nov. 2010, Refereed, Not invited

Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development.
Ishitobi, H; Matsumoto, K; Azami, T; Itoh, F; Itoh, S; Takahashi, S; Ema, M
Exp Anim., Jun. 2010, Refereed, Not invited

Subventricular Zone-Derived Neural Progenitor Cells Migrate Along a Blood Vessel Scaffold Toward the Post-stroke Striatum
Takuro Kojima; Yuki Hirota; Masatsugu Ema; Satoru Takahashi; Ichiro Miyoshi; Hideyuki Okano; Kazunobu Sawamoto
STEM CELLS, Mar. 2010, Refereed, Not invited

Flk1-GFP BAC Tg mice: An animal model for the study of blood vessel development
Hiroyuki Ishitobi; Ken Matsumoto; Takuya Azami; Fumiko Itoh; Susumu Itoh; Satoru Takahashi; Masatsugu Ema
Experimental Animals, 2010, Refereed, Not invited

Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model
Ken Matsumoto; Naoshi Obara; Masatsugu Ema; Masaki Horie; Ayano Naka; Satoru Takahashi; Shigehiko Imagawa
CANCER SCIENCE, Sep. 2009, Refereed, Not invited

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation
Fumiko Itoh; Susumu Itoh; Rita L. C. Carvalho; Tomomi Adachi; Masatsugu Ema; Marie-Jose Goumans; Jonas Larsson; Stefan Karlsson; Satoru Takahashi; Christine L. Mummery; Peter ten Dijke; Mitsuyasu Kato
LABORATORY INVESTIGATION, Jul. 2009, Refereed, Not invited

Kruppel-like factor 5 Is Essential for Blastocyst Development and the Normal Self-Renewal of Mouse ESCs
Masatsugu Ema; Daisuke Mori; Hitoshi Niwa; Yoshikazu Hasegawa; Yojiro Yamanaka; Seiji Hitoshi; Junsei Mimura; Yoh-ichi Kawabe; Tomohiro Hosoya; Masanobu Morita; Daisuke Shimosato; Kazuhiko Uchida; Norio Suzuki; Jun Yanagisawa; Kazuhiro Sogawa; Janet Rossant; Masayuki Yamamoto; Satoru Takahashi; Yoshiaki Fujii-Kuriyama
CELL STEM CELL, Nov. 2008, Not refereed, Not invited

Genetic evidence of PEBP2 beta-independent activation of Runx1 in the murine embryo
Tomomasa Yokomizo; Masatoshi Yanagida; Gang Huang; Motomi Osato; Chikako Honda; Masatsugu Ema; Satoru Takahashi; Masayuki Yamamoto; Yoshiaki Ito
INTERNATIONAL JOURNAL OF HEMATOLOGY, Sep. 2008, Refereed, Not invited

Runx1 is involved in primitive erythropoiesis in the mouse
Tomomasa Yokomizo; Kazuteru Hasegawa; Hiroyuki Ishitobi; Motomi Osato; Masatsugu Erna; Yoshiaki Lto; Masayuki Yamamoto; Satoru Takahashi
BLOOD, Apr. 2008, Not refereed, Not invited

Compensatory signalling induced in the yolk sac vasculature by deletion of TGF beta receptors in mice
Rita L. C. Carvalho; Fumiko Itoh; Marie-Jose Goumans; Franck Lebrin; Mitsuyasu Kato; Satoru Takahashi; Masatsugu Ema; Susumu Itoh; Marga van Rooijen; Philippe Bertolino; Peter ten Dijke; Christine L. Mummery
JOURNAL OF CELL SCIENCE, Dec. 2007, Refereed, Not invited

Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo
Tomomasa Yokomizo; Satoru Takahashi; Naomi Mochizuki; Takashi Kuroha; Masatsugu Ema; Asami Wakamatsu; Ritsuko Shimizu; Osamu Ohneda; Motomi Osato; Hitoshi Okada; Toshihisa Komori; Minetaro Ogawa; Shin-Ichi Nishikawa; Yoshiaki Ito; Masayuki Yamamoto
EMBO JOURNAL, Jan. 2007, Not refereed, Not invited

Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo
Masatsugu Ema; Tomomasa Yokomizo; Asami Wakamatsu; Tsumoru Terunuma; Masayuki Yamamoto; Satoru Takahashi
BLOOD, Dec. 2006, Not refereed, Not invited

Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival
T Wada; JJ Haigh; M Ema; S Hitoshi; R Chaddah; J Rossant; A Nagy; D van der Kooy
JOURNAL OF NEUROSCIENCE, Jun. 2006, Not refereed, Not invited

Vascular endothelial growth factor A signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival
Vera Eremina; Shiying Cui; Hanspeter Gerber; Napoleone Ferrara; Jody Haigh; Andras Nagy; Masatsugu Ema; Janet Rossant; Serge Jothy; Jeffrey H. Miner; Susan E. Quaggin
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Mar. 2006, Not refereed, Not invited

Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors
M Ema; S Takahashi; J Rossant
BLOOD, Jan. 2006, Not refereed, Not invited

Rapid isolation of glomeruli coupled with gene expression profiling identifies downstream targets in Pod1 knockout miceLE
SY Cui; CJ Li; M Ema; J Weinstein; SE Quaggin
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Nov. 2005, Refereed, Not invited

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells
JJ Haigh; M Ema; K Haigh; M Gertsenstein; P Greer; J Rossant; A Nagy; EF Wagner
BLOOD, Feb. 2004, Not refereed, Not invited

Cell fate decisions in early blood vessel formation
M Ema; J Rossant
TRENDS IN CARDIOVASCULAR MEDICINE, Aug. 2003, Not refereed, Not invited

Heterodimers of bHLH-PAS protein fragments derived from AhR, AhRR, and Arnt prepared by co-expression in Escherichia coli: Characterization of their DNA binding activity and preparation of a DNA complex
Y Kikuchi; S Ohsawa; J Mimura; M Ema; C Takasaki; K Sogawa; Y Fujii-Kuriyama
JOURNAL OF BIOCHEMISTRY, Jul. 2003, Not refereed, Not invited

HLF/HIF-2 alpha is a key factor in retinopathy of prematurity in association with erythropoietin
M Morita; O Ohneda; T Yamashita; S Takahashi; N Suzuki; O Nakajima; S Kawauchi; M Ema; S Shibahara; T Udono; K Tomita; M Tamai; K Sogawa; M Yamamoto; Y Fujii-Kuriyama
EMBO JOURNAL, Mar. 2003, Not refereed, Not invited

Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse
M Ema; P Faloon; WL Zhang; M Hirashima; T Reid; WL Stanford; S Orkin; K Choi; J Rossant
GENES & DEVELOPMENT, Feb. 2003, Not refereed, Not invited

成体での血管新生におけるHLFの役割
守田 匡伸; 高橋 智; 中島 修; 大根田 絹子; 山下 年晴; 依馬 正次; 柴原 茂樹; 鵜殿 徹男; 富田 浩史; 玉井 信
生化学, Aug. 2001

Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice
Tomonori Hosoya; Yoshihito Oda; Satoru Takahashi; Masanobu Morita; Shimako Kawauchi; Masatsugu Ema; Masayuki Yamamoto; Yoshiaki Fujii-Kuriyama
Genes to Cells, 2001, Not refereed, Not invited

Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome
M Ema; S Ikegami; T Hosoya; J Mimura; H Ohtani; K Nakao; K Inokuchi; M Katsuki; Y Fujii-Kuriyama
HUMAN MOLECULAR GENETICS, Aug. 1999, Not refereed, Not invited

Molecular mechanisms of transcription activation by HLF and HIF1 alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300
M Ema; K Hirota; J Mimura; H Abe; J Yodoi; K Sogawa; L Poellinger; Y Fujii-Kuriyama
EMBO JOURNAL, Apr. 1999, Refereed, Not invited, URL

Identification of a novel mechanism of regulation of Ah (dioxin) receptor function
J Mimura; M Ema; K Sogawa; Y Fujii-Kuriyama
GENES & DEVELOPMENT, Jan. 1999, Not refereed, Not invited

cDNA cloning and predicted primary structure of scallop sarcoplasmic reticulum Ca2+-ATPase (vol 119, pg 777, 1998)
Y Nagata; T Yamamoto; M Ema; J Mimura; Y Fujii-Kuriyama; T Suzuki; T Furukohri; K Konishi; D Sato; G Tajima; J Nakamura
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, Nov. 1998, Refereed, Not invited

Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and Clock
S Takahata; K Sogawa; A Kobayashi; M Ema; J Mimura; N Ozaki; Y Fujii-Kuriyama
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 1998, Not refereed, Not invited

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia
K Sogawa; K Numayama-Tsuruta; M Ema; M Abe; H Abe; Y Fujii-Kuriyama
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jun. 1998, Not refereed, Not invited

cDNA cloning and predicted primary structure of scallop sarcoplasmic reticulum Ca2+-ATPase
Yoshiaki Nagata; Taibo Yamamoto; Masatsugu Ema; Junsei Mimura; Yoshiaki Fujii-Kuriyama; Tomohiko Suzuki; Takahiro Furukohri; Kazuhiko Konishi; Dai Sato; Genichi Tajima; Jun Nakamura
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 1998, Refereed, Not invited

Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor
J Mimura; K Yamashita; K Nakamura; M Morita; TN Takagi; K Nakao; M Ema; K Sogawa; M Yasuda; M Katsuki; Y FujiiKuriyama
GENES TO CELLS, Oct. 1997, Refereed, Not invited, URL

Regulation of dioxin receptor function by omeprazole
N Dzeletovic; J McGuire; M Daujat; J Tholander; M Ema; Y FujiiKuriyama; J Bergman; P Maurel; L Poellinger
JOURNAL OF BIOLOGICAL CHEMISTRY, May 1997, Not refereed, Not invited

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 alpha regulates the VEGF expression and is potentially involved in lung and vascular development
M Ema; S Taya; N Yokotani; K Sogawa; Y Matsuda; Y FujiiKuriyama
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 1997, Refereed, Not invited, URL

cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)
K Hirose; M Morita; M Ema; J Mimura; H Hamada; H Fujii; Y Saijo; O Gotoh; K Sogawa; Y FujiiKuriyama
MOLECULAR AND CELLULAR BIOLOGY, Apr. 1996, Refereed, Not invited, URL

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis
Masatsugu Ema; Masanobu Morita; Shuntaro Ikawa; Masahiro Tanaka; Youichi Matsuda; Osamu Gotoh; Yukio Saijoh; Hideta Fujii; Hiroshi Hamada; Yasuo Kikuchi; Yoshiaki Fujii-Kuriyama
Molecular and Cellular Biology, 1996, Not refereed, Not invited

cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization
M Ema; M Suzuki; M Morita; K Hirose; K Sogawa; Y Matsuda; O Gotoh; Y Saijoh; H Fujii; H Hamada; Y FujiiKuriyama
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jan. 1996, Not refereed, Not invited

cDNA cloning and tissue specific expression of a novel bHLH/PAS factor (Arnt2) with close sequence similarity to AhR nuclear translocator (Arnt)
Mol. Cell. Biol., 1996, Not refereed, Not invited

POLYMORPHIC FORMS OF THE AH RECEPTOR AND INDUCTION OF THE CYP1A1 GENE
Y FUJIIKURIYAMA; M EMA; J MIMURA; N MATSUSHITA; K SOGAWA
PHARMACOGENETICS, 1995, Not refereed, Not invited

A COMPLETE STRUCTURE OF THE MOUSE AH RECEPTOR GENE
J MIMURA; M EMA; K SOGAWA; S IKAWA; Y FUJIIKURIYAMA
PHARMACOGENETICS, Dec. 1994, Refereed, Not invited, URL

DIOXIN BINDING ACTIVITIES OF POLYMORPHIC FORMS OF MOUSE AND HUMAN ARYLHYDROCARBON RECEPTORS
M EMA; N OHE; M SUZUKI; J MIMURA; K SOGAWA; S IKAWA; Y FUJIIKURIYAMA
JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 1994, Refereed, Not invited, URL

HUMAN ARYLHYDROCARBON RECEPTOR - FUNCTIONAL EXPRESSION AND CHROMOSOMAL ASSIGNMENT TO 7P21
M EMA; N MATSUSHITA; K SOGAWA; T ARIYAMA; J INAZAWA; T NEMOTO; M OTA; M OSHIMURA; Y FUJIIKURIYAMA
JOURNAL OF BIOCHEMISTRY, Oct. 1994, Refereed, Not invited, URL

AH RECEPTOR - A NOVEL LIGAND-ACTIVATED TRANSCRIPTION FACTOR
Y FUJIIKURIYAMA; M EMA; J MIMURA; K SOGAWA
EXPERIMENTAL AND CLINICAL IMMUNOGENETICS, 1994, Refereed, Not invited, URL

A FACTOR-BINDING TO THE XENOBIOTIC RESPONSIVE ELEMENT (XRE) OF P-4501A1 GENE CONSISTS OF AT LEAST 2 HELIX-LOOP-HELIX PROTEINS, AH RECEPTOR AND ARNT
N MATSUSHITA; K SOGAWA; M EMA; A YOSHIDA; Y FUJIIKURIYAMA
JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 1993, Refereed, Not invited, URL

CDNA CLONING AND STRUCTURE OF MOUSE PUTATIVE AH RECEPTOR
M EMA; K SOGAWA; N WATANABE; Y CHUJOH; N MATSUSHITA; O GOTOH; Y FUNAE; Y FUJIIKURIYAMA
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 1992, Refereed, Not invited

遺伝子改変霊長類を用いたヒト多発性嚢胞腎の疾患モデリング
依馬正次
日本実験動物学会総会講演要旨集(Web), 2025

Possible involvement of α2-antiplasmin in cerebrovascular development
岡村萌子; 河下映里; 石原慶一; 依馬正次; 松尾理; 秋葉聡
日本薬学会年会要旨集(Web), 2024

Elucidation of interaction between perifollicular vessel and dermal papilla cell
鍵山怜那; ZENG Ying; 高島さつき; 高島さつき; 河野美夕; 岡本正志; 依馬正次; 市橋正光; 水谷健一
日本薬学会年会要旨集(Web), 2024

APPトランスジェニックカニクイザルの脳脊髄液バイオマーカーの変化
柳沢大治郎; 守村敏史; 西村正樹; 辻敬一; 辻篤司; 遠山育夫; 依馬正次; 石垣診祐
Dementia Japan, 2024

日本におけるカニクイサル等(非ヒト霊長類)の需要と供給の現状把握と不足見込み数の推計並びに今後の検討・提言に向けた研究 アカデミアでの学術研究におけるカニクイザル等の不足に対応するための発生工学技術・技術者育成・飼育状況の実勢把握
依馬正次; 中村紳一朗
日本におけるカニクイサル等(非ヒト霊長類)の需要と供給の現状把握と不足見込み数の推計並びに今後の検討・提言に向けた研究 令和5年度 総括・分担研究報告書(Web), 2024

マウス妊娠時の子宮における血管内皮増殖因子受容体(Flt1およびFlk1)の発現変化
大友茉奈; 財部駿介; 川田由以; 影山敦子; 依馬正次; 寺川純平; 伊藤潤哉; 柏崎直巳
日本分子生物学会年会プログラム・要旨集(Web), 2024

APP遺伝子改変カニクイザルのアルツハイマー病脳脊髄液バイオマーカーの解析
柳沢大治郎; 守村敏史; 西村正樹; 遠山育夫; 依馬正次; 石垣診祐
日本生物学的精神医学会(Web), 2024

カニクイザルにおけるAMHの加齢性変化の検討
花田哲郎; 辻俊一郎; 竹林明枝; 小原実穂; サビツカ エディタ; 山海直; 依馬正次; 村上節
日本生殖内分泌学会学術集会プログラム・抄録集(Web), 2024

APPトランスジェニックカニクイザルの開発 脳脊髄液バイオマーカー
柳沢 大治郎; 守村 敏史; 西村 正樹; 遠山 育夫; 依馬 正次; 石垣 診祐
Dementia Japan, Oct. 2023

試験管内人工着床系開発に向けたカニクイザル着床期子宮内膜オルガノイドの構築
松本 翔馬; 小原 実穂; 山海 直; 依馬 正次
Journal of Mammalian Ova Research, Apr. 2023

心臓の発達に寄与するRNA結合タンパク質のin vivoスクリーニング
三上 夏輝; 村田 和弥; 依馬 朋香; 佐藤 優芽; 依馬 正次; 水野 聖哉; 杉山 文博
日本内分泌学会雑誌, Mar. 2023

Establishment of efficient transgenic technology for rapid phenotyping in mice
岡村永一; 水野聖哉; 松本翔馬; 水谷英二; 増山七海; 増山七海; 増山七海; 木島佑輔; 谷本陽子; 加藤花名子; 鈴木颯; WOLTJEN Knut; 高橋智; 杉山文博; 谷内江望; 谷内江望; 谷内江望; 谷内江望; 依馬正次
日本ゲノム編集学会大会要旨集, 2023

Similarities and differences in placental development between humans and cynomolgus monkeys
Shoma Matsumoto; Eiichi Okamura; Masanaga Muto; Masatsugu Ema
Reproductive Medicine and Biology, 2023

Exoc3l4 is essential for placental angiogenesis in mice.
高島さつき; 武藤真長; 渡部千里; 岡村永一; 松本翔馬; 築山智之; 藤井勢津子; 久保田慶顕; 水野聖哉; 杉山文博; 高橋智; 水谷健一; 依馬正次
日本分子生物学会年会プログラム・要旨集(Web), 2023

マウス胎盤の血管新生におけるExoc3l4遺伝子の機能解明
高島さつき; 武藤真長; 岡村永一; 松本翔馬; 久保田義顕; 水野聖哉; 杉山文博; 高橋智; 水谷健一; 依馬正次
日本血管生物医学会学術集会プログラム・抄録集, 2023

PiggyBACトランスポゾンを用いたトランスジェニック動物作製法の効率化
岡村 永一; 松本 翔馬; 水野 聖哉; 谷本 陽子; 加藤 花名子; 鈴木 颯; 依馬 正次
日本生化学会大会プログラム・講演要旨集, Nov. 2022

増大特集 革新脳と関連プロジェクトから見えてきた新しい脳科学 Ⅰ.霊長類脳科学 a)遺伝子改変技術および関連技術を用いたマーモセットの脳科学･疾患研究 マカクにおける遺伝子改変技術と疾患モデルの作製
松本 翔馬; 依馬 正次
生体の科学, 15 Oct. 2022

カニクイザルを用いた生命科学研究の最新動向
岡村 永一; 依馬 正次
遺伝子医学 = Gene & medicine, Oct. 2022

ノックアウトマウスのオンターゲット毒性情報を候補化合物の開発にどのように結びつけるのか-事例紹介 PKD1ノックアウトカニクイザルの作製・解析と今後の展開
依馬 正次
The Journal of Toxicological Sciences, Jun. 2022

Creation and analysis of PKD1 knock-out cynomolgus monkeys and the future direction
EMA Masatsugu
Annual Meeting of the Japanese Society of Toxicology, 2022

遺伝子改変技術の新展開 非ヒト霊長類の1種であるカニクイザルにおける遺伝子改変技術の進展
依馬 正次; 岡村 永一
日本生化学会大会プログラム・講演要旨集, Nov. 2021

非ヒト霊長類の1種であるカニクイザル胎盤に由来する栄養膜幹細胞の樹立
岡村 永一; 武藤 真長; 松本 翔馬; Jargalsaikhan Bat-Erdene; 依馬 正次
日本生化学会大会プログラム・講演要旨集, Nov. 2021

非ヒト霊長類の1種であるカニクイザル胎盤に由来する栄養膜幹細胞の樹立
岡村 永一; 武藤 真長; 松本 翔馬; Jargalsaikhan Bat-Erdene; 依馬 正次
日本生化学会大会プログラム・講演要旨集, Nov. 2021

迅速な心筋特異的ノックアウトマウスシステムの開発
依馬 朋香; 村田 知弥; 岡村 永一; 三上 夏輝; 松本 翔馬; 水野 聖哉; 依馬 正次; 杉山 文博
日本生化学会大会プログラム・講演要旨集, Nov. 2021

Generation of ADKPD model in non-human primate and pathological analyses at juvenile lineage.
松本翔馬; 依馬正次
月刊腎臓内科, Nov. 2021

ユニークな実験動物を用いた医学研究(Vol.9) カニクイザル ヒト橋渡し研究の大本命
武藤 真長; 依馬 正次
医学のあゆみ, Nov. 2021

Functional analysis of Exocyst complex in mice spermatogenesis
MIKAMI Natsuki; MURATA Kazuya; EMA Masatsugu; TAKAHASHI Satoru; MIZUNO Seiya; SUGIYAMA Fumihiro
The Journal of Reproduction and Development Supplement, Nov. 2021

A MONKEY PKD1 MUTANT RECAPITULATES HUMAN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
小林憲市; 小林憲市; 築山智之; 中家雅隆; 依馬正次; 河内明宏
日本小児泌尿器科学会雑誌, Jun. 2021
https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2021&ichushi_jid=J02877&link_issn=&doc_id=20210624400004&doc_link_id=%2Fdw5syohi%2F2021%2F003001%2F005%2F0026-0036%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdw5syohi%2F2021%2F003001%2F005%2F0026-0036%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

Human disease modeling with genetically-modified cynomologus monkey, a nonhuman primate
岡村永一; 依馬正次
Bio Clinica, May 2021

Histological analysis of vascular aging in the brain from VEGFR-1, VEGFR-2 and VEGFR-3 reporter mice.
齋尾真吾; 齋尾真吾; 渡部千里; 渡部千里; 岩井亮太; 岡本正志; 市橋正光; 依馬正次; 水谷健一
日本薬学会年会要旨集(Web), Mar. 2021

バイオマテリアルとしてのカニクイザル不死化Bリンパ球バンクの構築
守村敏史; 伊藤靖; 等誠司; 遠山育夫; 依馬正次
日本獣医学会学術集会講演要旨集, 2021

Regularity of the Vessel Network in the Skin Tissue Alters with Aging
高島さつき; 高島さつき; 朝山紗衣; 朝山紗衣; 岩崎彩夏; 岩崎彩夏; 鈴木真理子; 森山麻里子; 森山博由; 市橋正光; 依馬正次; 水谷健一
日本香粧品学会誌, Sep. 2020

研究者の最新動向 非ヒト霊長類の1種であるカニクイザルを用いたヒト疾患モデリング
依馬 正次; 岡村 永一
Precision Medicine, Jun. 2020

Vascular niche in the skin dramatically changes with aging
朝山紗衣; 朝山紗衣; 高島さつき; 高島さつき; 鈴木真理子; 森山麻里子; 森山博由; 依馬正次; 岡本正志; 市橋正光; 水谷健一
日本薬学会年会要旨集(CD-ROM), Mar. 2020

非ヒト霊長類のトランスクリプトーム・アトラス
廣瀬直毅; 廣瀬直毅; 依馬正次; 佐々木えりか; GUSEV Oleg; GUSEV Oleg; 河合純; 村川泰裕; 村川泰裕; 川路英哉; 川路英哉; 川路英哉
日本分子生物学会年会プログラム・要旨集(Web), 2020

遺伝子改変カニクイザルを用いた常染色体多発性嚢胞腎モデリング
依馬正次
日本分子生物学会年会プログラム・要旨集(Web), 2020

VEGF受容体リポーターマウスを用いた脳血管老化の組織学的解析
齋尾真吾; 齋尾真吾; 渡部千里; 渡部千里; 岩井亮太; 岡本正志; 市橋正光; 依馬正次; 水谷健一
日本分子生物学会年会プログラム・要旨集(Web), 2020

異なる培養条件で樹立したカニクイザル栄養膜幹細胞の比較解析
松本翔馬; 武藤真長; 岡村永一; JARGALSAIKHAN Bat-Erdene; 田中智; 依馬正次
日本分子生物学会年会プログラム・要旨集(Web), 2020

アルツハイマー病関連変異型amyloid precursor protein発現トランスジェニックカニクイザルの作出
守村 敏史; 清田 弥寿成; 渡邊 直希; 岩谷 千鶴; 土屋 英明; 中村 紳一郎; 鈴木 利治; 依馬 正次; 西村 正樹; 遠山 育夫
日本脳科学会プログラム・抄録集, Nov. 2019

【血管新生-基礎と臨床】血管新生解析 蛍光レポーターマウスを用いた血管発生および血管新生研究の新展開
依馬 正次; 渡部 千里
医学のあゆみ, Jul. 2019

DNA/RNAを標的とする医療技術の現状と安全性評価の考え方 霊長類DNA/RNAデータベースの構築と医療への応用
河合 純; 廣瀬 直毅; 佐野 浩美; 岡崎 康司; 八木 研; 山本 由美子; 依馬 正次; 清田 弥寿成; 築山 智之; 中家 雅隆; 佐々木 えりか; 井上 貴史; 渡部 聡朗; 榊原 康文; Jayakumar Vasanthan; 内藤 雄樹; 村川 泰裕; 川路 英哉
The Journal of Toxicological Sciences, Jun. 2019

Human disease modeling with genetically modified cynomolgus monkeys
EMA Masatsugu
Annual Meeting of the Japanese Society of Toxicology, Jun. 2019

小児泌尿器科疾患:成育医療へのリレー 基礎研究が切り開く成育医療の未来
小林 憲市; 築山 智之; 影山 進; 依馬 正次; 河内 明宏
日本泌尿器科学会総会, Apr. 2019

Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†.
Seita Yasunari; Tsukiyama Tomoyuki; Azami Takuya; Kobayashi Kenichi; IWATANI Chizuru; TSUCHIYA Hideaki; Nakaya Masataka; Tanabe Hideyuki; Hitoshi Seiji; Miyoshi Hiroyuki; Nakamura Shin-ichiro; Kawauchi Akihiro; Ema Masatsugu; 清田 弥寿成; 築山 智之; 浅見 拓哉; 小林 憲市; 岩谷 千鶴; 土屋 英明; 中家 雅隆; 等 誠司; 中村 紳一郎; 河内 明宏; 依馬 正次
Biology of Reproduction, 14 Mar. 2019
http://hdl.handle.net/10422/00012485

皮膚組織における血管構築の規則性と加齢に伴う破綻
高島さつき; 高島さつき; 鈴木真理子; 森山麻里子; 市橋正光; 岡本正志; 依馬正次; 森山博由; 水谷健一
日本薬学会年会要旨集(CD-ROM), Mar. 2019, Not refereed, Not invited

皮膚組織における血管構築の規則性と加齢に伴う破綻
高島 さつき; 鈴木 真理子; 森山 麻里子; 市橋 正光; 岡本 正志; 依馬 正次; 森山 博由; 水谷 健一
日本薬学会年会要旨集, Mar. 2019

原腸胚の胚葉形成を可視化するレポーターマウスの作製
鈴木颯; TRA Thi Huong Dinh; 大徳陽子; 加藤花名子; 飯島沙織; 浅見拓哉; 依馬正次; 水野聖哉; 水野聖哉; 杉山文博; 杉山文博
日本実験動物学会総会講演要旨集(Web), 2019

血管内皮細胞に高発現するエキソサイトーシス関連分子が担う新たな血管新生機構
渡部千里; 一山悠介; 築山勢津子; 築山智之; 水野聖哉; 高橋智; 依馬正次
日本分子生物学会年会プログラム・要旨集(Web), 2019

血管内皮細胞に高発現するExocyst Complexが果たす生理的役割
渡部千里; 渡部千里; 一山悠介; 藤井勢津子; 中山あずさ; 田村勝; 水野聖哉; 高橋智; 依馬正次
日本心血管内分泌代謝学会学術総会プログラム及び抄録集, 2019

PKD医学の最先端 CRISPR/Cas9を用いたADPKDモデルカニクイザルの作出と解析
依馬 正次; 築山 智之; 小林 憲市; 和泉 博之; 河内 明宏
日本腎臓学会誌, Aug. 2018, Not refereed, Not invited

Vegfr3レポーターマウスの作製と発現解析
渡部千里; 松下淳; 浅見拓哉; 築山(藤井)勢津子; 築山智之; 水野聖哉; 高橋智; 依馬正次
日本分子生物学会年会プログラム・要旨集(Web), 2018

Vegfr3レポーターマウスの作製と発現解析
渡部千里; 松下淳; 浅見拓哉; 築山(藤井)勢津子; 築山智之; 水野聖哉; 高橋智; 依馬正次
日本血管生物医学会学術集会プログラム・抄録集, 2018

Effect of the promoter on GFP expression and development of promoter evaluation system in cynomolgus monkey
SEITA Yasunari; TSUKIYAMA Tomoyuki; AZAMI Takuya; IWATANI Chizuru; TSUCHIYA Hideaki; NAKAMURA Shinichiro; EMA Masatsugu
The Journal of Reproduction and Development Supplement, 2018

核酸医薬創薬に資する霊長類オミックスデータベースの構築
河合純; 川路英哉; 村川泰裕; 佐野浩美; 依馬正次; 清田弥寿成; 築山智之; 中家雅隆; 佐々木えりか; 井上貴史; 渡部聡朗
日本核酸医薬学会年会講演要旨集, 2018

CRISPR/Cas9を用いた疾患モデルカニクイザルの作出
築山 智之; 小林 憲市; 岩谷 千鶴; 土屋 英明; 清田 弥寿成; 松下 淳; 北嶋 郁; 河本 育士; 中川 孝博; 福田 浩司; 岩切 哲平; 和泉 博之; 板垣 伊織; 中村 紳一朗; 河内 明宏; 依馬 正次
生命科学系学会合同年次大会, Dec. 2017, Not refereed, Not invited

VEGFR3レポーターマウスの作成と発現解析
渡部千里; 松下淳; 浅見拓哉; 築山(藤井)勢津子; 築山智之; 高橋智; 依馬正次
日本心血管内分泌代謝学会学術総会プログラム及び抄録集, 2017

組織内の規則的な血管発生は,神経幹細胞の分裂を調節する
水谷健一; 水谷健一; 鈴木真理子; 岩井亮太; 山西恵美子; 渡部千里; 手島羽香; 田畑秀典; 永田浩一; 木下和生; 依馬正次
再生医療, 2017

全身でGFPを発現するトランスジェニックカニクイザルの作製
清田弥寿成; 築山智之; 岩谷千鶴; 松下淳; 土屋英明; 佐々木えりか; 依馬正次
Journal of Reproduction and Development, 2016

Molecular Profiling of Vascular Endothelial Cells
松本 健; 依馬 正次
細胞工学, 2016

発生期大脳皮質に形成される無血管領域は,分裂する神経幹細胞と血管内皮細胞の接触を調節する
水谷健一; 水谷健一; 岩井亮太; 鈴木真理子; 山西恵美子; 田畑秀典; 渡部千里; 手島羽香; 木下和夫; 原田浩; 永田浩一; 依馬正次
日本分子生物学会年会プログラム・要旨集(Web), 2016

発生期大脳皮質における血管発生の規則性とその生理機能の役割
渡部千里; 丸山(大高)千秋; 鈴木真理子; 岩井亮太; 山西恵美子; 山本渉子; 依馬正次; 水谷健一; 水谷健一
日本分子生物学会年会プログラム・要旨集(Web), 2016

Knock in of expression-amplifying pluripotent-stem-cell reporters using CRISPR/Cas9 into mouse and cynomolgus monkey pluripotent stem cells.
TSUKIYAMA Tomoyuki; NIWA Hitoshi; IWATANI Chizuru; TSUCHIYA Hideaki; SEITA Yasunari; MATSUSHITA Jun; EMA Masatsugu
The Journal of Reproduction and Development Supplement, 2015

ヒトおよびカニクイザル多能性幹細胞の培養におけるWnt阻害剤の影響
築山 智之; 依馬 正次
日本繁殖生物学会 講演要旨集, 2014

Klf5による多能性幹細胞維持機構
浅見 拓哉; 松本 健; 全 孝静; 高橋 智; 依馬 正次
日本繁殖生物学会 講演要旨集, 2013

Role of Klf gene family in the self-renewal of mouse ES cells
EMA Masatsugu
生化學, 25 Apr. 2010

Chondroitin Sulfate Is Essential for Normal Endochondral Ossification
佐藤隆; 工藤崇; 池原譲; 小川寛恭; 平野朋子; 清原克恵; 萩原梢; 栂谷内晶; 依馬正次; 高橋智; 木全弘治; 渡辺秀人; 成松久
バイオテクノロジーシンポジウム予稿集, 2010

Kruppel-like Factors in Stem Cell Biology
Masatsugu Ema; Satoru Takahashi; Yoshiaki Fujii-Kuriyama
BIOLOGY OF KRUPPEL-LIKE FACTORS, 2009, Refereed, Not invited

Role of SCL/Tall on endothelial and hematopoietic development
EMA Masatsugu
生化學, 25 Nov. 2003

The structure and physiological function of bHLH-PAS transcription factors
M Ema
SEIKAGAKU, Feb. 2001, Refereed, Not invited
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035257401&partnerID=MN8TOARS

bHLH-PAS型転写因子群の構造とその生理機能
依馬 正次
生化学 / 日本生化学会 編, 2001

新生マウスの酸素負荷網膜症発症モデルの血管新生におけるHLFの役割
守田 匡伸; 中島 修; 高橋 智; 川内 紫真子; 山下 年晴; 依馬 正次; 柴原 茂樹; 鵜殿 徹男; 富田 浩史; 玉井 信
生化学, Aug. 2000

Molecular mechanism of hypoxia-inducible transcriptional activation by bHLH-PAS transcription factors
EMA Masatsugu; SUGIBAYASHI Chiaki; HIROTA Kichi; YODOI Junji; FUJII-KURIYAMA Yoshiaki
日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998

HIF-1 α and HLF regulate expression of endothelial cell-specific tyrosine kinaseTie2 through upstream HRE sequence
ABE Manabu; EMA Masatsugu; FUJII-KURIYAMA Yoshiaki
日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998

Identification of transcriptional repression domain and celluar localization of mSim1 and mSim2
OHNO Hiromichi; EMA Masatsugu; FUJII-KURIYAMA Yoshiaki
日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998

Systematics of sarcoplasmic reticulum/endoplasmic reticulum type calcium transport ATPase from the viewpoint of amino acid sequence.
永田善明; 山本泰望; 依馬正次; 藤井義明; 鈴木知彦; 古郡隆弘; 小西和彦; 佐藤大; 中村準
日本動物学会大会予稿集, 1998

Ahリセプター類似の抑制型転写因子の構造と機能解析
三村 純正; 依馬 正次; 十川 和博; 藤井 義明
日本分子生物学会年会プログラム・講演要旨集, 01 Aug. 1996

AhRおよびArntのDNA結合領域 : 大腸菌による発現とDNA結合活性をもつヘテロ二量体の形成
菊池 康夫; 依馬 正次; 十川 和博; 藤井 義明
日本分子生物学会年会プログラム・講演要旨集, 01 Aug. 1996

マウス胚におけるダイオキシン受容体, AhRの発現パターン
守田 匡伸; 依馬 正次; 三村 純正; 山下 敬介; 安田 峯生; 勝木 元也; 中村 健司; 中尾 和貴; 藤井 義明
日本分子生物学会年会プログラム・講演要旨集, 01 Aug. 1996

DNA-BINDING REGULATORY FACTORS AND INDUCIBLE EXPRESSION OF THE P4501A1 GENE
K SOGAWA; N MATSUSHITA; M EMA; Y FUJIIKURIYAMA
CYTOCHROME P450, 1994, Refereed, Not invited

カニクイザルにおける遺伝子改変技術と疾患モデル
武藤真長; 依馬正次
生体の科学, 2025

カニクイザルの生殖関連ホルモンの開発
守村敏史; 依馬正次
生体の科学, 2025

大特集 革新脳と関連プロジェクトから見えてきた新しい脳科学 Ⅰ.霊長類脳科学 a)遺伝子改変技術および関連技術を用いたマーモセットの脳科学･疾患研究 マカクにおける遺伝子改変技術と疾患モデルの作製
松本 翔馬; 依馬 正次
生体の科学, 2022

カニクイザルを用いた生命科学研究の最新動向
岡村 永一; 依馬 正次
遺伝子医学 = Gene & medicine, 2022

血管を研究するためのモデル動物〜マウスを中心に
高島さつき; 依馬正次
化学同人, 2022

遺伝子改変カニクイザルを用いたヒト疾患モデリング
岡村永一; 依馬正次
オベリスク, 2021

モデル動物の作製と利用－循環器疾患
松本翔馬; 依馬正次
エル・アイ・シー, 2021

カニクイザル―ヒト橋渡し研究の大本命
武藤真長; 依馬正次
医学のあゆみ, 2021

非ヒト霊長類を用いたADPKDモデルの作出と幼若期における病態解析
松本翔馬; 依馬正次
腎臓内科, 2021

遺伝子改変カニクイザルを用いたヒト疾患モデリング
岡村永一; 依馬正次, Joint work
BIO clinica, 2021

非ヒト霊長類の１種であるカニクイザルを用いたヒト疾患モデリング
依馬 正次; 岡村 永一, Joint work
Precision Medicine, Jun. 2020

血管新生─基礎と臨床 蛍光レポーターマウスを用いた血管発生および血管新生研究の新展開
依馬 正次; 渡部 千里
医学のあゆみ, Jul. 2019

マウス表現型解析パーフェクトガイド、第3章-6 胚性致死
築山 智之; 依馬 正次, Joint work
実験医学別冊, Nov. 2016

血管内皮細胞特異的分子プロファイリング
松本健; 依馬正次, Joint work
細胞工学, May 2016

発生期における血管形成制御因子の網羅解析
依馬正次; 吉原雅大, Joint work
血管医学, Dec. 2013

モデル動物利用マニュアル 第１章 発生・形態形成 第6項 血球系
依馬 正次, Single work
Feb. 2011

マウス ES 細胞の未分化性維持における Klf 転写因子群の役割
依馬 正次, Single work
生化学, Apr. 2010

胚性幹細胞の樹立とその自己複製におけるKlf5の役割
依馬正次、長谷川賀一、高橋 智、藤井義明, Joint work
実験医学, Jun. 2009

血管内皮・血球細胞の発生・分化におけるｂHLH型転写因子SCL／Tallの役割
依馬 正次, Single work
生化学, Nov. 2003

Flk1とTal1の協調的作用による血管内皮・血球発生の制御
依馬 正次, Single work
細胞工学, Jul. 2003

酸素分圧による遺伝子発現制御機構
共立出版酸化ストレス・レドックスの生化学, 2000, Not refereed

Apr. 2008, Present
日本実験動物学会

Apr. 2006, Present
日本解剖学会

日本血管生物医学会

日本再生医療学会

日本癌学会

日本分子生物学会

日本生化学会

非ヒト霊長類の着床、胎盤形成機構の解明とヒトへの展開
挑戦的研究(開拓)
滋賀医科大学
28 Jun. 2024, 31 Mar. 2028

Pathological and diagnostic significance of the N-terminal fragment of TDP-43 in ALS
Grant-in-Aid for Scientific Research (C)
Shiga University of Medical Science
01 Apr. 2024, 31 Mar. 2027

in vivo development of non-human primate blastoids
Grant-in-Aid for Scientific Research (B)
Tokyo Medical and Dental University
01 Apr. 2023, 31 Mar. 2026

新規ミトコンドリア蛋白質の構造異常によるALS病態の解析と評価モデル系の開発
基盤研究(B)
滋賀医科大学
01 Apr. 2022, 31 Mar. 2026

新規ミトコンドリア蛋白質の構造異常によるALS病態の解析と評価モデル系の開発
基盤研究(B)
滋賀医科大学
01 Apr. 2022, 31 Mar. 2026

PKD遺伝子異常に伴う脳動脈瘤発生の病態解明
基盤研究(C)
滋賀医科大学
01 Apr. 2022, 31 Mar. 2025

Reconstitution of implantation process with primate endometrial organoid
Grant-in-Aid for Challenging Research (Exploratory)
Shiga University of Medical Science
30 Jun. 2022, 31 Mar. 2024

霊長類の内部細胞塊ダイナミズムと全能性
新学術領域研究(研究領域提案型)
滋賀医科大学
01 Apr. 2022, 31 Mar. 2024

Developing a versatile technique to create transgenic rodents and medium sized animals
Grant-in-Aid for Scientific Research (B)
Shiga University of Medical Science
01 Apr. 2021, 31 Mar. 2024

Evaluating the role of cis-regulatory tandem DNA repeats in human disease and evolution
基盤研究(B)
京都大学
01 Apr. 2021, 31 Mar. 2024

Development of in vitro chimera assay system utilizing cynomolgus monkey embryos
Grant-in-Aid for Scientific Research (B)
01 Apr. 2020, 31 Mar. 2023

Origin of placental tissues in cynomolgus monkey
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Shiga University of Medical Science
01 Apr. 2020, 31 Mar. 2022

Development of diagnosis and therapy for aging using a nonhuman primate model of premature aging
Grant-in-Aid for Scientific Research (C)
Shiga University of Medical Science
01 Apr. 2019, 31 Mar. 2022

Development of genome editing technique in monkey and it's application to ADPKD monkey model
Grant-in-Aid for Challenging Research (Exploratory)
Shiga University of Medical Science
28 Jun. 2019, 31 Mar. 2021

Elucidation of the molecular mechanism to maintain hierarchical structure of vascular system and and tumour angiogenesis
Grant-in-Aid for Scientific Research (B)
Shiga University of Medical Science
01 Apr. 2018, 31 Mar. 2021

Molecular analysis of the proteasome gene expression and its application to anti-aging.
Grant-in-Aid for Scientific Research (B)
Doshisha University
01 Apr. 2016, 31 Mar. 2019

Molecular bases for masking c-MYC dependent apoptosis common in embryonic stem cells and cancer cells
Grant-in-Aid for Scientific Research (B)
Saitama Medical University
01 Apr. 2016, 31 Mar. 2019

Development of new in vivo imaging technologies by using biological optical window
Grant-in-Aid for Scientific Research (S)
University of Tsukuba
30 May 2014, 31 Mar. 2019

Development and application of advanced non-invasive imaging system for mice
Grant-in-Aid for Scientific Research (B)
University of Tsukuba
01 Apr. 2015, 31 Mar. 2018

Anti-angiogenic therapy for brain tumors targeting neuro-vascular wiring molecules
Grant-in-Aid for Scientific Research (B)
University of Tsukuba
01 Apr. 2015, 31 Mar. 2018

New technique to sort cells expressing a gene of interest
Grant-in-Aid for Challenging Exploratory Research
Shiga University of Medical Science
01 Apr. 2015, 31 Mar. 2017

Generations of mice for imaging of cardiovascular system
Grant-in-Aid for Scientific Research (B)
Shiga University of Medical Science
01 Apr. 2014, 31 Mar. 2017

Development of a premature aging syndrome non-human primate model
Grant-in-Aid for Challenging Exploratory Research
Shiga University of Medical Science
01 Apr. 2014, 31 Mar. 2017

Eradication of cancer cells by controlling Max and/or nucleostemin expression
Grant-in-Aid for Scientific Research (B)
Saitama Medical University
01 Apr. 2013, 31 Mar. 2016

Anti-angiogenic therapy for glioma beyond VEGF inhibition based on tumor microenvironment
Grant-in-Aid for Scientific Research (B)
University of Tsukuba
01 Apr. 2012, 31 Mar. 2016

血管と諸器官のワイアリング機構
新学術領域研究(研究領域提案型)
滋賀医科大学
01 Apr. 2013, 31 Mar. 2015

Development of basic technologies for new in vivo imaging to promote life science research
Grant-in-Aid for Scientific Research (S)
University of Tsukuba
11 May 2009, 31 Mar. 2014

Klfファミリーによる幹細胞機能制御の分子機構
筑波大学
2009, 2014

血管内皮細胞と諸器官のワイアリング機構の解明
新学術領域研究(研究領域提案型)
筑波大学
01 Apr. 2011, 31 Mar. 2013

Analysis of physiological functions of novel endothelial-enriched genes
Grant-in-Aid for Scientific Research (C)
2011, 2013

Progress of anti-angiogenic therapy for brain tumors : new modality and resolution of the resistance
Grant-in-Aid for Scientific Research (B)
University of Tsukuba
2009, 2011

Elucidation of functional roles of new genes in angiogenesis
Grant-in-Aid for Scientific Research (C)
University of Tsukuba
2008, 2010

Flk1陽性多能性中胚葉細胞と周囲細胞群の運命決定機構
特定領域研究
筑波大学
2008, 2009

Klf5による幹細胞維持機構
特定領域研究
筑波大学
2008, 2009

Antiangiogenic therapy using endothelial progenitor cells for malignant tumors
Grant-in-Aid for Scientific Research (C)
University of Tsukuba
2006, 2008

血管新生に於ける新規遺伝子群の機能解明
基盤研究(C)
筑波大学
2007, 2007

Wnt誘導型転写因子BTEB2の幹細胞維持における生理機能の解明
特定領域研究
筑波大学
2005, 2006

血液、血管、幹細胞の発生学的研究
2002, 2006

Developmental biology of blood, blood vessels and stem cells
2002, 2006

血島を構成する未分化中胚葉細胞からの血管内皮・血球細胞の発生機構
特定領域研究
筑波大学
2003, 2004

特願2021-135524, 脂質異常症モデル動物
扇田久和; 佐藤朗; 依馬正次; 築山智之

特開2019-216666, 特願2018-117705, 早期老化症モデル動物
伊藤 靖; 小笠原 一誠; 依馬 正次; 築山 智之; 土屋 英明; 石垣 宏仁