Nov. 2012
立命館イノベーションフェア2012, 立命館イノベーションフェア研究奨励賞・研究機構部門最優秀賞

Sustained Notch activation depletes adult neural stem cells and impairs cognitive function.
Nur Azrah Fazera Mohd Ariffin; Naoko Morimura; Kenny Daun; Seiji Hitoshi
Scientific reports, 16 Jun. 2026, Refereed

Klf5 regulates the transition from apical radial glia to intermediate progenitor cells in the developing mammalian brain.
Takahiro Fuchigami; Yoshitaka Hayashi; Anri Kuroda; Zakiyyah Munirah Mohd Zaki; Nur Azrah Fazera Mohd Ariffin; Kenny Anak Daun; Naoko Morimura; Hiroaki Kitagawa; Takuya Azami; Shoji Tatsumoto; Yasuhiro Go; Kazuhiko Uchida; Satoru Takahashi; Kazuhiko Nakabayashi; Masatsugu Ema; Seiji Hitoshi
The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 Mar. 2026, Refereed

Glial cells missing 1 triggers gliosis and angiogenesis after neonatal brain injury.
Yoshitaka Hayashi; Asmaa Abdullah; Satoshi Fuke; Nur Azrah Fazera Mohd Ariffin; Kenny Anak Daun; Naoko Morimura; Kazuhiko Nakabayashi; Shoji Tatsumoto; Yasuhiro Go; Toshihiko Hosoya; Seiji Hitoshi
iScience, 21 Nov. 2025, Refereed

Role of α1,3-fucosyltransferases in the mammalian brain and their association with neuropsychiatric disorders.
Asmaa Abdullah; Yoshitaka Hayashi; Naoko Morimura; Seiji Hitoshi
Trends in Glycoscience and Glycotechnology, Jul. 2024, Refereed

Depletion of transit amplifying cells in the adult brain does not affect quiescent neural stem cell pool size.
Zakiyyah Munirah Mohd Zaki; Anri Kuroda; Naoko Morimura; Yoshitaka Hayashi; Seiji Hitoshi
The journal of physiological sciences : JPS, 13 Sep. 2023, Refereed

Conformational change of RNA-helicase DHX30 by ALS/FTD-linked FUS induces mitochondrial dysfunction and cytosolic aggregates.
Ryota Hikiami; Toshifumi Morimura; Takashi Ayaki; Tomoyuki Tsukiyama; Naoko Morimura; Makiko Kusui; Hideki Wada; Sumio Minamiyama; Akemi Shodai; Megumi Asada-Utsugi; Shin-Ichi Muramatsu; Takatoshi Ueki; Ryosuke Takahashi; Makoto Urushitani
Scientific reports, 26 Sep. 2022, Refereed

Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation.
Kei-Ichi Katayama; Naoko Morimura; Katsunori Kobayashi; Danielle Corbett; Takehito Okamoto; Veravej G Ornthanalai; Hayato Matsunaga; Wakako Fujita; Yoshifumi Matsumoto; Takumi Akagi; Tsutomu Hashikawa; Kazuyuki Yamada; Niall P Murphy; Soichi Nagao; Jun Aruga
iScience, 15 Jul. 2022, Refereed

Fut9 Deficiency Causes Abnormal Neural Development in the Mouse Cerebral Cortex and Retina.
Asmaa Abdullah; Yoshitaka Hayashi; Naoko Morimura; Akhilesh Kumar; Kazuhiro Ikenaka; Akira Togayachi; Hisashi Narimatsu; Seiji Hitoshi
Neurochemical research, 26 Jun. 2022, Refereed

Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics
Misato Ichise; Kazuto Sakoori; Kei-ichi Katayama; Naoko Morimura; Kazuyuki Yamada; Hiroki Ozawa; Hayato Matsunaga; Minoru Hatayama; Jun Aruga
FRONTIERS IN MOLECULAR NEUROSCIENCE, May 2022, Refereed

Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG.
Seiya Oura; Taichi Noda; Naoko Morimura; Seiji Hitoshi; Hiroshi Nishimasu; Yoshitaka Nagai; Osamu Nureki; Masahito Ikawa
Communications biology, 23 Jun. 2021, Refereed

Nephronectin Expression is Inhibited by Inorganic Phosphate in Osteoblasts.
Tadashi Kato; Atsushi Yamada; Kiyohito Sasa; Kentaro Yoshimura; Naoko Morimura; Hiroaki Ogata; Akiko Sakashita; Ryutaro Kamijo
Calcified tissue international, Feb. 2019, Refereed, Not invited

FGF-2 suppresses expression of nephronectin via JNK and PI3K pathways
Tadashi Kato; Atsushi Yamada; Mikiko Ikehata; Yuko Yoshida; Kiyohito Sasa; Naoko Morimura; Akiko Sakashita; Takehiko Iijima; Daichi Chikazu; Hiroaki Ogata; Ryutaro Kamijo
FEBS Open Bio, 01 May 2018, Refereed, Not invited

Altered monoamine dynamics and abnormal behaviors in Lrtm2-deficient mice
Ichise Misato; Katayama Keiichi; Sakoori Kazuto; Morimura Naoko; Hatayama Minoru; Aruga Jun
Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018, Not refereed

IL-1 beta suppresses nephronectin expression in osteoblasts via ERK1/2 and JNK
Yuka Iezumi; Atsushi Yamada; Erika Minami; Mikiko Ikehata; Yuko Yoshida; Tadashi Kato; Naoko Morimura; Hiroaki Ogata; Akiko Sakashita; Takehiko Iijima; Daichi Chikazu; Ryutaro Kamijo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Nov. 2017, Refereed, Not invited

Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice
Naoko Morimura; Hiroki Yasuda; Kazuhiko Yamaguchi; Kei-ichi Katayama; Minoru Hatayama; Naoko H. Tomioka; Maya Odagawa; Akiko Kamiya; Yoshimi Iwayama; Motoko Maekawa; Kazuhiko Nakamura; Hideo Matsuzaki; Masatsugu Tsujii; Kazuyuki Yamada; Takeo Yoshikawa; Jun Aruga
NATURE COMMUNICATIONS, Jun. 2017, Refereed, Not invited, Corresponding

Altered brain monoamine contents and abnormal behaviors in Lrtm2-deficient mice
Ichise Misato; Katayama Kei-ichi; Sakoori Kazuto; Morimura Naoko; Ozawa Hiroki; Hatayama Minoru; Aruga Jun
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017, Refereed, Not invited

Wnt/beta-catenin signaling activates nephronectin expression in osteoblasts
Mikiko Ikehata; Atsushi Yamada; Naoko Morimura; Masakatsu Itose; Tetsuo Suzawa; Tatsuo Shirota; Daichi Chikazu; Ryutaro Kamijo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Mar. 2017, Refereed, Not invited

Expression of nephronectin is enhanced by 1 alpha,25-dihydroxyvitamin D-3
Katsuhiro Hiranuma; Atsushi Yamada; Tamaki Kurosawa; Ryo Aizawa; Dai Suzuki; Yoshiro Saito; Ryo Nagahama; Mikiko Ikehata; Masayuki Tsukasaki; Naoko Morimura; Daichi Chikazu; Koutaro Maki; Tatsuo Shirota; Masamichi Takami; Matsuo Yamamoto; Takehiko Iijima; Ryutaro Kamijo
FEBS OPEN BIO, Sep. 2016, Refereed, Not invited

Nephronectin Expression Is Up-Regulated by BMP-2
Tamaki Kurosawa; Atsushi Yamada; Dai Suzuki; Naoko Morimura; Yoshiyuki Sasagane; Hiroyuki Itabe; Ryutaro Kamijo
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Jul. 2016, Refereed, Not invited

Altered monoamine dynamics and exploratory behavior in Lrtm2-deficient mice
Ichise Misato; Katayama Kei-ichi; Sakoori Kazuto; Morimura Naoko; Hatayama Minoru; Aruga Jun
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2016, Refereed, Not invited

Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathways
Tamaki Kurosawa; Atsushi Yamada; Masamichi Takami; Dai Suzuki; Yoshiro Saito; Katsuhiro Hiranuma; Takuya Enomoto; Naoko Morimura; Matsuo Yamamoto; Takehiko Iijima; Tatsuo Shirota; Hiroyuki Itabe; Ryutaro Kamijo
FEBS OPEN BIO, 2015, Refereed, Not invited

Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures
Naoko H. Tomioka; Hiroki Yasuda; Hiroyuki Miyamoto; Minoru Hatayama; Naoko Morimura; Yoshifumi Matsumoto; Toshimitsu Suzuki; Maya Odagawa; Yuri S. Odaka; Yoshimi Iwayama; Ji Won Um; Jaewon Ko; Yushi Inoue; Sunao Kaneko; Shinichi Hirose; Kazuyuki Yamada; Takeo Yoshikawa; Kazuhiro Yamakawa; Jun Aruga
NATURE COMMUNICATIONS, Jul. 2014, Refereed, Not invited

Role of Elfn1 in hippocampal inhibitory neural circuits containing somatostatin-positive neurons
Naoko Tomioka; Hiroyuki Miyamoto; Minoru Hatayama; Naoko Morimura; Yoshifumi Matsumoto; Toshimitsu Suzuki; Yoshimi Iwayama; Kazuyuki Yamada; Takeo Yoshikawa; Kazuhiro Yamakawa; Jun Aruga
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014, Refereed, Not invited

Rines E3 Ubiquitin Ligase Regulates MAO-A Levels and Emotional Responses
Miyuki Kabayama; Kazuto Sakoori; Kazuyuki Yamada; Veravej G. Ornthanalai; Maya Ota; Naoko Morimura; Kei-ichi Katayama; Niall P. Murphy; Jun Aruga
JOURNAL OF NEUROSCIENCE, Aug. 2013, Refereed, Not invited

Nephronectin expression is regulated by SMAD signaling in osteoblast-like MC3T3-E1 cells
Masayuki Tsukasaki; Atsushi Yamada; Kentaro Yoshimura; Agasa Miyazono; Matsuo Yamamoto; Masamichi Takami; Yoichi Miyamoto; Naoko Morimura; Ryutaro Kamijo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Aug. 2012, Refereed, Not invited

Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-alpha
Masayuki Tsukasaki; Atsushi Yamada; Dai Suzuki; Ryo Aizawa; Agasa Miyazono; Yoichi Miyamoto; Tetsuo Suzawa; Masamichi Takami; Kentaro Yoshimura; Naoko Morimura; Matsuo Yamamoto; Ryutaro Kamijo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2011, Refereed, Not invited

Impaired Cognitive Function and Altered Hippocampal Synapse Morphology in Mice Lacking Lrrtm1, a Gene Associated with Schizophrenia
Noriko Takashima; Yuri S. Odaka; Kazuto Sakoori; Takumi Akagi; Tsutomu Hashikawa; Naoko Morimura; Kazuyuki Yamada; Jun Aruga
PLOS ONE, Jul. 2011, Refereed, Not invited

Executive dysfunction in novel environment and altered hippocampal synapse morphology in mice lacking Lrrtm1
Takashima Noriko; Odaka Yuri; Sakoori Kazuto; Akagi Takumi; Hashikawa Tsutomu; Morimura Naoko; Yamada Kazuyuki; Aruga Jun
Neuroscience Research, 2011, Refereed, Not invited

Lrfn2/SALM1 regulates excitatory synapse function in the hippocampus and its deficient mice display mental disorder-like behavioral abnormalities
Naoko Morimura; Hiroki Yasuda; Kazuyuki Yamada; Naoko H. Tomioka; Kei-ichi Katayama; Kazuhiko Yamaguchi; Maya Ota; Akiko Kamiya; Jun Aruga
NEUROSCIENCE RESEARCH, 2011, Refereed, Not invited

Slitrk5-deficient mice display elevated anxiety-like behavior and serotonergic abnormalities
Yoshifumi Matsumoto; Kei-ichi Katayama; Naoko Morimura; Kazuyuki Yamada; V. G. Ornthanalai; Maya Ota; Niall P. Murphy; Jun Aruga
NEUROSCIENCE RESEARCH, 2009, Refereed, Not invited

Lrfn2/SALM1, a synaptic leucine-rich repeat transmembrane molecule is required for proper synapse maturation and brain function
Naoko Morimura; Maya Ota; Hiroki Yasuda; Kei-ichi Katayama; Naoko Hara; Kazuyuki Yamada; Kazuhiko Yamaguchi; Jun Aruga
NEUROSCIENCE RESEARCH, 2009, Refereed, Not invited

TGF-beta suppresses POEM expression through ERK1/2 and JNK in osteoblasts
Agasa Miyazono; Atsushi Yamada; Naoko Morimura; Masamichi Takami; Dai Suzuki; Makoto Kobayashi; Ken-ichi Tezuka; Matsuo Yamamoto; Ryutaro Kamijo
FEBS LETTERS, Nov. 2007, Refereed, Not invited

Lrfn2/SALM1, a synaptic leucine-rich repeat-containing transmembrane protein regulates synapse formation and function
Naoko Morimura; Kei-ichi Katayama; Kazuhiko Yamaguchi; Maya Ota; Akiko Kamiya; Jun Aruga
NEUROSCIENCE RESEARCH, 2007, Refereed, Not invited

Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins
Naoko Morimura; Takashi Inoue; Kei-ichi Katayama; Jun Aruga
GENE, Oct. 2006, Refereed, Not invited

Establishment of primary cultures for mouse ameloblasts as a model of their lifetime
T Suzawa; N Itoh; N Takahashi; T Katagiri; N Morimura; Y Kobayashi; T Yamamoto; R Kamijo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2006, Refereed, Not invited

Lrfn2, a neuronal leucine-rich repeat-containing transmembrane protain can interact with PSD-95
Naoko Morimura; Takashi Inoue; Kei-ichi Katayama; Jun Aruga
NEUROSCIENCE RESEARCH, 2006, Refereed, Not invited

Interleukin-1 beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner
R Yasuhara; Y Miyamoto; T Akaike; T Akuta; M Nakamura; M Takami; N Morimura; K Yasu; R Kamijo
BIOCHEMICAL JOURNAL, Jul. 2005, Refereed, Not invited

Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins
T Takada; T Katagiri; M Ifuku; N Morimura; M Kobayashi; K Hasegawa; A Ogamo; R Kamijo
JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2003, Refereed, Not invited

Suppression of differentiation and proliferation of early chondrogenic cells by Notch
N Watanabe; Y Tezuka; K Matsuno; S Miyatani; N Morimura; M Yasuda; R Fujimaki; K Kuroda; Y Hiraki; N Hozumi; K Tezuka
JOURNAL OF BONE AND MINERAL METABOLISM, 2003, Refereed, Not invited

新規細胞接着分子POEM(pre-osteoblast EGF-like repeat protein with MAM domain)の骨及び歯胚における解析
守村 直子; 笹金 宜之; 片桐 岳信; 須澤 徹夫; 上條 竜太郎
昭和歯学会雑誌, Dec. 2002

Stimulation of osteoblastic cell differentiation by Notch
K Tezuka; M Yasuda; N Watanabe; N Morimura; K Kuroda; S Miyatani; N Hozumi
JOURNAL OF BONE AND MINERAL RESEARCH, Feb. 2002, Refereed, Not invited

Molecular cloning of POEM - A novel adhesion molecule that interacts with alpha(8)beta(1) integrin
N Morimura; Y Tezuka; N Watanabe; M Yasuda; S Miyatani; N Hozumi; K Tezuka
JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2001, Refereed, Not invited

DEVELOPMENT OF GLYCOSIDE-BOUND RADIOPHARMACEUTICALS - NOVEL RADIOIODINATION METHOD FOR DIGOXIN
Y TAKEMURA; Y FUJIBAYASHI; N DOTE; H TANIUCHI; N IIJIMA; J KONISHI; A YOKOYAMA
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Jan. 1994, Refereed, Not invited

Basic evaluation of67Ga labeled digoxin derivative as a metal-labeled bifunctional radiopharmaceutical
Yasuhisa Fujibayashi; Yasutaka Takemura; Hideyuki Taniuchi; Naoko Iijima; Junji Konishi; Akira Yokoyama
Annals of Nuclear Medicine, Dec. 1993, Refereed, Not invited

Functional analysis of LRFN2 on bidirectional interactions between GBM and neurons
林千裕; DAUN Kenny; 深見忠輝; 額田康貴; 山本哲哉; 守村直子; 等誠司
日本解剖学会総会・全国学術集会抄録集(CD-ROM), 2025

Pathological significance of a genetic mutant form of LRFN2 in glioblastoma
吉澤琢磨; DAUN Kenny; 深見忠輝; 守村直子; 等誠司
日本解剖学会総会・全国学術集会抄録集(CD-ROM), 2025

Roles of H2B E3 Ubiquitin ligase, RNF20 in gliomagenesis
DAUN Kenny; MORIMURA Naoko; TANIGAKI Kenji; TSUKIYAMA Tomoyuki; HAYASHI Yoshitaka; KOYAMA Natsu; SHIINO Akihiko; FUKAMI Tadateru; NOZAKI Kazuhiko; GO Yasuhiro; HITOSHI Seiji
日本生物学的精神医学会(Web), 2024

マルチスピーシーズ霊長類の知識型脳画像データ共有エコプラットフォームの構築:オープンサイエンスが拓く脳科学の新境界
酒井朋子; 新宅勇太; 込山悠介; 林正治; 守村直子; 浦山慎一; 岡田知久; 山地一禎
情報処理学会研究報告(Web), 2024

The effect of microglia on behavior
Rina Sugimoto; Shimada Itsuki; Nakatani Jin; Sawano Toshinori; Morimura Naoko; Hitoshi Seiji; Tanaka Hidekazu
Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2023, Not refereed

シナプス接着分子を介する学習障害(LD)の分子神経基盤
守村 直子
先進医薬研究振興財団研究成果報告集, Mar. 2021

加齢マウスにおける不安行動の増大および海馬のシナプス分子の減少
横川 拓海; 守村 直子; 高坂 和芳; 木戸 康平; 秦 侑希; 山本 かえで; 菅 唯志; 田中 秀和; 三品 昌美; 林 達也; 藤田 聡
生命科学系学会合同年次大会, Dec. 2017

加齢マウスにおける不安行動の増大および海馬のシナプス分子の減少
横川 拓海; 守村 直子; 高坂 和芳; 木戸 康平; 秦 侑希; 山本 かえで; 菅 唯志; 田中 秀和; 三品 昌美; 林 達也; 藤田 聡
生命科学系学会合同年次大会, Dec. 2017, Not refereed, Not invited

マウスの探索行動とモノアミン代謝に関与するLrtm2タンパク質の分子機能
ICHISE Misato; KATAYAMA Kei-ichi; SAKOORI Kazuto; MORIMURA Naoko; HATAYAMA Minoru; HATAYAMA Minoru; ARUGA Jun; ARUGA Jun
日本分子生物学会年会プログラム・要旨集(Web), 2016

Oncostatin Mによるネフロネクチン発現制御機構の解明
黒澤 珠希; 山田 篤; 高見 正道; 鈴木 大; 守村 直子; 板部 洋之; 上條 竜太郎
日本薬学会年会要旨集, Mar. 2015

神経細胞におけるミトコンドリアバイオジェネシス関連シグナル経路の再検証
横川拓海; 守村直子; 三品昌美; 田中秀和; 藤田隆司; 岩中伸壮; 林達也; 橋本健志
日本分子生物学会年会プログラム・要旨集(Web), 2014

探索行動を制御する神経膜タンパク質Lrtm2の分子機能
市瀬実里; 片山圭一; 佐郡和人; 守村直子; 小田川摩耶; 富岡直子; 山田一之; 畑山実; 有賀純
日本分子生物学会年会プログラム・要旨集(Web), 2014, Not refereed, Not invited

ユビキチンリガーゼRinesによるモノアミンオキシダーゼ(MAO-A)分解を介した情動行動制御機構
樺山 実幸; 佐郡 和人; 山田 一之; 小田川 摩耶; 守村 直子; 片山 圭一; Murphy Niall P.; 有賀 純
日本獣医学会学術集会講演要旨集, Aug. 2013

乳酸は神経細胞におけるミトコンドリアバイオジェネシスを誘発する
横川拓海; 山本直樹; 守村直子; 三品昌美; 田中秀和; 橋本健志
日本分子生物学会年会プログラム・要旨集(Web), 2013

【シナプスをめぐるシグナリング】 受容体 AMPA受容体の発現調節
守村 直子
生体の科学, Oct. 2010, Not refereed, Not invited

LRR膜貫通分子Lrfn2/SALM1は海馬興奮性シナプスの形態や機能調節および可塑性に関与する
守村直子; 山口和彦; 安田浩樹; 片山圭一; 原直子; 太田摩耶; 神谷明子; 有賀純
生化学, 2008, Not refereed, Not invited

シナプス接着分子Lrfn2/SALM1ノックアウトマウスにみられた統合失調症様行動異常
守村直子; 太田摩耶; 山田一之; 原直子; 片山圭一; 有賀純
生化学, 2008, Not refereed, Not invited

TGF-beta suppresses POEM expression in osteoblasts
A. Miyazono; A. Yamada; N. Morimura; D. Suzuki; M. Kobayashi; M. Takami; K. Tezuka; M. Yamamoto; R. Kamijo
JOURNAL OF BONE AND MINERAL RESEARCH, Sep. 2007, Not refereed, Not invited

TGF-βは骨芽細胞においてPOEMの発現を抑制する
宮園 あがさ; 山田 篤; 守村 直子; 小林 誠; 高見 正道; 手塚 建一; 山本 松男; 上條 竜太郎
日本骨代謝学会学術集会プログラム抄録集, Jun. 2007

脳神経組織特異的膜貫通分子Lrfn2はシナプス後膜肥厚タンパク質PSD-95と結合する。
守村直子; 井上貴史; 片山圭一; 有賀純
日本分子生物学会年会講演要旨集, 2005

脊椎動物中枢神経系形成のダイナミズム Slitrkファミリー膜貫通蛋白質の神経発生における役割(Dynamism in vertebrate CNS development: The role of Slitrk transmembrane protein family in neural development)
有賀 純; 片山 圭一; 守村 直子; 佐藤 愛
神経化学, Aug. 2004

BMPの活性はヘパリンによって促進される
高田貴虎; 小林誠; 長谷川紘司; 片桐岳信; 守村直子; 上条竜太郎
日本歯周病学会学術大会プログラムおよび講演抄録集, 2004

脳神経組織に発現する新規leucine-rich repeatファミリーLrfn1-5の分子比較解析
守村直子; 井上貴史; 片山圭一; 有賀純
日本分子生物学会年会プログラム・講演要旨集, 2004

Heparin enhances the bmp activity by prolonging the BMP action through direct interaction
T Takada; T Katagiri; N Morimura; M Kobayashi; K Hasegawa; R Kamijo
BONE, May 2003, Not refereed, Not invited

ヘパリンによる骨誘導因子(BMP)活性の促進機構
高田 貴虎; 小林 誠; 長谷川 紘司; 片桐 岳信; 守村 直子; 上條 竜太郎; 伊福 道代
昭和歯学会雑誌, Mar. 2003

新規細胞接着分子POEM (Pre-Osteoblast EGF-like repeat protein with MAM domain) の解析と会合する分子の同定
笹金 宜之; 穂積 信道; 守村 直子; 片桐 岳信; 上條 竜太郎; 手塚 建一
生物物理化学, 15 Oct. 2002, Not refereed, Not invited

新規細胞接着分子POEMの単離と機能解析
守村 直子; 片桐 岳信; 須澤 徹夫; 上條 竜太郎
歯科基礎医学会雑誌, 20 Sep. 2002, Not refereed, Not invited

エナメル芽細胞の分化に伴う遺伝子発現の変化
須澤 徹夫; 片桐 岳信; 守村 直子; 上條 竜太郎
歯科基礎医学会雑誌, 20 Sep. 2002, Not refereed, Not invited

BMPによるId1とOsterixの発現調節機構
片桐 岳信; 守村 直子; 上條 竜太郎
歯科基礎医学会雑誌, 20 Sep. 2002, Not refereed, Not invited

POEM: A novel pre-osteoblastic ligand molecule for alpha 8 beta 1 integrin.
N Morimura; Y Tezuka; N Watanabe; M Yasuda; S Miyatani; N Hozumi; K Tezuka
JOURNAL OF BONE AND MINERAL RESEARCH, Sep. 2001, Not refereed, Not invited

Notch下流転写因子HES-1による軟骨細胞分化制御
渡辺 尚子; 手塚 洋子; 守村 直子; 安田 雅文; 穂積 信道; 手塚 建一
日本骨代謝学会雑誌, Jul. 2001

活性型Notch,BMP受容体によるヒト骨髄間葉系幹細胞の骨芽細胞様分化の促進
安田雅文; 渡辺尚子; 守村直子; 穂積信道; 手塚建一
日本骨代謝学会雑誌, 2001

細胞接着分子POEM(pre-osteoblast EGF-like repeat protein with MAM domain)はα8β1インテグリンのリガンドである
守村直子; 手塚洋子; 渡辺尚子; 安田雅文; 穂積信道; 手塚建一
日本骨代謝学会雑誌, 2001

Actions of notch on osteoblastic and chondrogenic cell differentiation.
K Tezuka; N Watanabe; N Morimura; Y Hiraki; N Hozumi
JOURNAL OF BONE AND MINERAL RESEARCH, Sep. 2000, Not refereed, Not invited

NotchはHes-1を介して軟骨細胞分化を抑制する
渡辺尚子; 松野健治; 開祐司; 守村直子; 安田雅文; 穂積信道; 手塚建一
日本分子生物学会年会プログラム・講演要旨集, 2000

活性型Notchは軟骨細胞様細胞株ATDC5の結節形成と基質産生を抑制する
渡辺 尚子; 守村 直子[飯島]; 開 祐司; 穂積 信道; 手塚 建一
日本骨代謝学会雑誌, Jun. 1999

活性型Notchは骨芽細胞と軟骨細胞の分化を異なった方向に制御する
手塚建一; 渡辺尚子; 守村直子; 宮谷精二; 開祐司; 穂積信道
日本分子生物学会年会プログラム・講演要旨集, 1999

Physiological significance on adult neurogenesis by Notch activation.
Mohd Ariffin NAF; Morimura N.; Daun KA; Zaki ZMM; Hitoshi S.
KSBN-APSN, 2024

Functional roles of a synaptic adhesion molecule, LRFN2, in gliomagenesis.
Yoshizawa T.; Daun K.; Fukami, T.; Morimura N.; Hitoshi S.
第101回日本生理学会年会, 2024

Expression and malignant role of an extracellular matrix integrin a8b1 ligand, POEM/NPNT in glioblastoma.
Morimura N.; Daun K.; Igarashi Y.; Fukami, T.; Hitoshi S.
ISN-ESN, 2023

Autism-like behaviors and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice.
Morimura N.; Yasuda H.; Yamaguchi K.; Katayama K.; Tomioka NH; Yamada K.; Hitoshi S.; Yoshikawa T.; Aruga J.
The 10th IBRO World Congress of Neuroscience IBRO2019, 2019, Not invited

シナプス接着分子Lrfn2/SALM1 から発達障害をLrfn2 遺伝子欠損マウスにみられた自閉症様行動と記憶機能およびシナプス可塑性の向上
守村 直子
第19回運動器科学研究会 若手招待講演, 2018, Invited

RNF20/BRE1a regulates proliferation and differentiation of GBM cancer stem-like cells.
Kenny Daun K.; Morimura N.; Fukami T.; Hayashi Y.; Koyama N.; Tanigaki K.; Shiino A.; Nozaki K.; Hitoshi S.
15th Meeting of the Asian-Pacific Society For Neurochemistry, 2017

こころの謎にせまる~神経細胞をつなぐ遺伝子と自閉症~
守村直子
東京理科大学生命科学研究科ミニシンポジウム, 2017, Invited

こころの謎にせまる~神経細胞をつなぐ遺伝子と自閉症~
守村直子
第4回立命館大学生命科学医科学コロキウム, 2016, Invited

Lrfn2/SALM1-deficient mice show neuropsychiatric disorder-like behavior phenotypes and synaptic changes of hippocampus
Morimura N.; Yasuda H.; Yamaguchi K.; Katayama K.; Yamada K.; Hara N.; Ota M.; Aruga J.
Neuroscience2012, 2012

Lrfn2/SALM1regulates excitatory synapse function in the hippocampus and its deficient mice display mental disorder-like behavioral abnormalities.
守村直子; 安田浩; 山田一之; 富岡直子; 片山圭一; 山口和彦; 太田摩耶; 神谷明子; 有賀純
第34回日本神経科学学会, 2011, Invited

Molecular Cloning of Associating Molecules with POEM.
Sasagane Y.; Morimura N.; Katagiri T.; Watanabe N.; Hozumi N.; Tezuka K.; Kamijo R.
The 1st IBMS-JSBMR Joint Meeting, Workshop, 2003

POEM: A Novel Pre-osteoblastic Ligand Molecule for α8b1 Integrin.
Morimura N.; Tezuka Y.; Watanabe N.; Yasuda M.; Hozumi N.; Tezuka K.
The 22th American Society for Bone and Mineral Research: ASBMR Plenary Poster, 2001

新規細胞接着分子POEM の単離と機能解析
守村(飯島)直子; 手塚洋子; 宮谷精二; 渡辺尚子; 穂積信道; 手塚建一
第23回日本分子生物学会 ワークショップ, 2000, Not invited

Introduction on medicine/medical life sciences
2021, Present, Shiga University of Medical Science

Neurophysiology
2020, Present, Shiga University of Medical Science

Physiology I
2020, Present, Shiga University of Medical Science

Emergency Medicine（Anatomy/Physiology）
2019, Present, 滋賀県消防学校

Introduction to basic medical research
2018, Present, Shiga University of Medical Science

Physiology Practice I
2016, Present, Shiga University of Medical Science

Oral Biochemistry Practice I
2002, 2004, Showa Medical University

日本分子生物学会

日本神経科学学会

Society for Neuroscience

日本生理学会

日本神経化学会

マルチスピーシーズ霊長類脳画像の知識型データ共有エコシステムの構築:データ駆動型脳科学を推進する共創型国際研究基盤
ユースケース創出課題
滋賀医科大学
Feb. 2024, Mar. 2026

Molecular mechanism underlying synapse development between neurons and glioma cells
Grant-in-Aid for Scientific Research (C)
Shiga University of Medical Science
Apr. 2022, Mar. 2026

Molecular Mechanisms of Neurodevelopmental Disorders mediated by the Synapse Adhesion Molecule LRFN2
Grant-in-Aid for Scientific Research (C)
Shiga University of Medical Science
01 Apr. 2019, 31 Mar. 2022

精神発達障害の分子メカニズムに基づいたトランレーショナル・リサーチの創出
基礎・臨床融合のプロジェクト
滋賀医科大学
2022

精神発達障害の分子メカニズムに基づいたトランレーショナル・リサーチの創出
基礎・臨床融合のプロジェクト
滋賀医科大学
2021

Molecular function of a synaptic adhesion molecule, SALM/Lrfn in the brain.
Grant-in-Aid for Scientific Research (C)
01 Apr. 2015, 31 Mar. 2019

シナプス接着分子を介する学習障害（LD）の分子神経基盤
精神薬療分野一般研究助成 発達障害
2019

自閉症および学習障害関連遺伝子LRFN2の非ヒト霊長類における分子制御機構の解明
滋賀医科大学
2018

学習障害（LD）関連遺伝子LRFN2のワーキングメモリ分子神経基盤
滋賀医科大学
2018

学習障害（LD）関連遺伝子Lrfn2の大脳皮質前頭連合野ワーキングメモリーにおける分子神経基盤
滋賀医科大学
2017

On the regulation of survival and death of synoviocytes and chondrocytes by nitric oxide
Grant-in-Aid for Scientific Research (C)
Showa University
2004, 2005

Studies on molecular mechanisms involved in differentiation of chondrocyte/osteoblast by Notch
Grant-in-Aid for Scientific Research (B)
Tokyo University of Science
2003, 2005

細胞接着分子POEMを介した骨および歯胚形成の分子メカニズムの解明
若手研究(B)
2003, 2004

Mechanisms of bone resorption in alveolar bone of IL-1 transgenic mice
Grant-in-Aid for Scientific Research (B)
2003, 2004

CHARACTERIZATION OF THE BONE FORMING FACTORS IN SERUM
Grant-in-Aid for Scientific Research (C)
SHOWA UNIVERSITY
2001, 2002

細胞接着分子POEMを介した骨・歯胚形成メカニズムの解明
若手
昭和大学
2002

新規Notchファミリー分子を介した骨芽細胞分化制御機構の解析
特別研究員奨励費
東京理科大学
1999, 2001