Sep. 2018
滋賀医科大学, 学長裁量経費（若手萌芽研究）研究助成

Dec. 2017
鈴木謙三記念医科学応用研究財団, 平成29年度助成金

Sep. 2017
滋賀医科大学, 学長裁量経費（若手萌芽研究）研究助成

Mar. 2017
滋賀医科大学, 滋賀医科大学シンポジウム 最優秀研究発表者賞（若鮎賞）

Endothelial RhoA is essential for embryonic and postnatal vascular development by regulating KLF2-Notch1 signaling.
Wondwossen Wale Tesega; Akio Shimizu; Taha Hussain; Fumiya Sawasaki; Lucia Sugawara; Shoma Matsumoto; Masatsugu Ema; Akira Sato; Hisakazu Ogita
Journal of biochemistry, 25 Apr. 2026

Suppression of the neutrophil-derived S100A8/A9 complex ameliorates doxorubicin-induced cardiomyopathy in non-human primates
Fumiya Sawasaki; Akira Sato; Akio Shimizu; Shoma Matsumoto; Ikuo Kawamoto; Mitsuru Murase; Iori Itagaki; Hideaki Tsuchiya; Hirohito Ishigaki; Naoko Ueda; Issa Toyoda; Yasushi Itoh; Daisuke Okuzaki; Masatsugu Ema; Hisakazu Ogita
Biochemical Pharmacology, Jan. 2026

Afadin Promotes Vascular Smooth Muscle Cell Contraction by Interacting With Phospholipase C to Enhance Ca2+ Signaling for Blood Pressure Regulation.
Md Mahbubur Rahman Khan; Akira Sato; Akio Shimizu; Shunji Suetaka; Md Rasel Molla; Masahiro Komeno; Mst Zenika Nasrin; Masanari Nishida; Futoshi Toyoda; Munehito Arai; Hisakazu Ogita
Arteriosclerosis, thrombosis, and vascular biology, Jul. 2025

EphA‐Mediated Regulation of Stomatin Expression in Prostate Cancer Cells
Masanari Nishida; Akira Sato; Akio Shimizu; Nor Idayu A. Rahman; Akinori Wada; Susumu Kageyama; Hisakazu Ogita
Cancer Medicine, 08 Oct. 2024, URL

前立腺癌におけるEphA-ERK-ELKシグナル伝達経路によるストマチンの発現制御
西田 将成; 佐藤 朗; 清水 昭男; Rahman Nor Idayu A.; 和田 晃典; 影山 進; 扇田 久和
日本癌治療学会学術集会抄録集, Oct. 2024

Establishment of a novel mouse model of renal artery coiling-based chronic hypoperfusion-related kidney injury
Yoshimi Imamura-Uehara; Mako Yasuda-Yamahara; Shogo Kuwagata; Kosuke Yamahara; Mamoru Yoshibayashi; Yuki Tanaka-Sasaki; Akio Shimizu; Hisakazu Ogita; Masami Chin-Kanasaki; Shinji Kume
Biochemistry and Biophysics Reports, Mar. 2024

Novel cardiovascular protective effects of RhoA signaling and its therapeutic implications
Joanne Ern Chi Soh; Akio Shimizu; Akira Sato; Hisakazu Ogita
Biochemical Pharmacology, Dec. 2023

Generation of a familial hypercholesterolemia model in non-human primate.
Akira Sato; Tomoyuki Tsukiyama; Masahiro Komeno; Chizuru Iwatani; Hideaki Tsuchiya; Ikuo Kawamoto; Mitsuru Murase; Takahiro Nakagawa; Iori Itagaki; Yasunari Seita; Shoma Matsumoto; Masataka Nakaya; Akio Shimizu; Atsushi Yamada; Masatsugu Ema; Hisakazu Ogita
Scientific reports, 20 Sep. 2023

Null mutation of exocyst complex component 3-like does not affect vascular development in mice.
Satsuki Takashima; Eiichi Okamura; Yusuke Ichiyama; Kiyoto Nishi; Akio Shimizu; Chisato Watanabe; Masanaga Muto; Shoma Matsumoto; Setsuko Tsukiyama-Fujii; Tomoyuki Tsukiyama; Hisakazu Ogita; Eiichiro Nishi; Masahito Ohji; Fumihiro Sugiyama; Satoru Takahashi; Seiya Mizuno; Ken-Ichi Mizutani; Masatsugu Ema
Experimental animals, 01 Sep. 2023

RhoA rescues cardiac senescence by regulating Parkin-mediated mitophagy.
Joanne Ern Chi Soh; Akio Shimizu; Md Rasel Molla; Dimitar P Zankov; Le Kim Chi Nguyen; Mahbubur Rahman Khan; Wondwossen Wale Tesega; Si Chen; Misa Tojo; Yoshito Ito; Akira Sato; Masahito Hitosugi; Shigeru Miyagawa; Hisakazu Ogita
The Journal of biological chemistry, Mar. 2023

Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity.
Md Rasel Molla; Akio Shimizu; Masahiro Komeno; Nor Idayu A Rahman; Joanne Ern Chi Soh; Le Kim Chi Nguyen; Mahbubur Rahman Khan; Wondwossen Wale Tesega; Si Chen; Xiaoling Pang; Miki Tanaka-Okamoto; Noriyuki Takashima; Akira Sato; Tomoaki Suzuki; Hisakazu Ogita
Communications biology, 07 Oct. 2022

Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment.
Akira Sato; Nor Idayu A Rahman; Akio Shimizu; Hisakazu Ogita
Cancer science, 22 Aug. 2021

Transmembrane protein 168 mutation reduces cardiomyocyte cell surface expression of Nav1.5 through αB-crystallin intracellular dynamics.
Le Kim Chi Nguyen; Akio Shimizu; Joanne Ern Chi Soh; Masahiro Komeno; Akira Sato; Hisakazu Ogita
Journal of biochemistry, 04 Jun. 2021

Cardio- and reno-protective effects of dipeptidyl peptidase III in diabetic mice.
Masahiro Komeno; Xiaoling Pang; Akio Shimizu; Md Rasel Molla; Mako Yasuda-Yamahara; Shinji Kume; Nor Idayu A Rahman; Joanne Ern Chi Soh; Le Kim Chi Nguyen; Mohammad Khusni B Ahmat Amin; Nao Kokami; Akira Sato; Yoshihiro Asano; Hiroshi Maegawa; Hisakazu Ogita
The Journal of biological chemistry, 07 May 2021

Stomatin-mediated inhibition of the Akt signaling axis suppresses tumor growth.
Nor Idayu A Rahman; Akira Sato; Khurelbaatar Tsevelnorov; Akio Shimizu; Masahiro Komeno; Mohammad Khusni Bin Ahmat Amin; Md Rasel Molla; Joanne Ern Chi Soh; Le Kim Chi Nguyen; Akinori Wada; Akihiro Kawauchi; Hisakazu Ogita
Cancer research, 23 Mar. 2021

Identification of transmembrane protein 168 mutation in familial Brugada syndrome.
Akio Shimizu; Dimitar P Zankov; Akira Sato; Masahiro Komeno; Futoshi Toyoda; Satoru Yamazaki; Toshinori Makita; Taichi Noda; Masahito Ikawa; Yoshihiro Asano; Yohei Miyashita; Seiji Takashima; Hiroshi Morita; Taisuke Ishikawa; Naomasa Makita; Masahito Hitosugi; Hiroshi Matsuura; Seiko Ohno; Minoru Horie; Hisakazu Ogita
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, May 2020, Refereed, Not invited

Anosmin-1 activates vascular endothelial growth factor receptor and its related signaling pathway for olfactory bulb angiogenesis.
Shoko Matsushima; Akio Shimizu; Manami Kondo; Hirotsugu Asano; Nobuhiro Ueno; Hironao Nakayama; Naoko Sato; Masahiro Komeno; Hisakazu Ogita; Misuzu Kurokawa-Seo
Scientific reports, 13 Jan. 2020, Refereed, Not invited

The Pivotal Roles of the Epithelial Membrane Protein Family in Cancer Invasiveness and Metastasis.
Ahmat Amin MKB; Shimizu A; Ogita H
Cancers, Oct. 2019, Refereed, Not invited

Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation
Noriaki Yamada; Yoshihiro Asano; Masashi Fujita; Satoru Yamazaki; Atsushi Inanobe; Norio Matsuura; Hatasu Kobayashi; Seiko Ohno; Yusuke Ebana; Osamu Tsukamoto; Saki Ishino; Ayako Takuwa; Hidetaka Kioka; Toru Yamashita; Norio Hashimoto; Dimitar P. Zankov; Akio Shimizu; Masanori Asakura; Hiroshi Asanuma; Hisakazu Kato; Yuya Nishida; Yohei Miyashita; Haruki Shinomiya; Nobu Naiki; Kenshi Hayashi; Takeru Makiyama; Hisakazu Ogita; Katsuyuki Miura; Hirotsugu Ueshima; Issei Komuro; Masakazu Yamagishi; Minoru Horie; Koichi Kawakami; Tetsushi Furukawa; Akio Koizumi; Yoshihisa Kurachi; Yasushi Sakata; Tetsuo Minamino; Masafumi Kitakaze; Seiji Takashima
Circulation, Apr. 2019, Refereed, Not invited

Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1.
Ahmat Amin MKB; Shimizu A; Zankov DP; Sato A; Kurita S; Ito M; Maeda T; Yoshida T; Sakaue T; Higashiyama S; Kawauchi A; Ogita H
Oncogene, Oct. 2018, Refereed, Not invited

Vascular endothelial growth factor-A exerts diverse cellular effects via small G proteins, Rho and Rap.
Shimizu A; Zankov DP; Kurokawa-Seo M; Ogita H
Int J Mol Sci, 2018, Refereed, Invited

Differential effects of myocardial afadin on pressure overload-Induced compensated cardiac hypertrophy.
Zankov DP; Sato A; Shimizu A; Ogita H
Circ J, 2017, Refereed, Not invited

Protective effects of intercalated disk protein afadin on chronic pressure overload-induced myocardial damage
Dimitar P. Zankov; Akio Shimizu; Miki Tanaka-Okamoto; Jun Miyoshi; Hisakazu Ogita
SCIENTIFIC REPORTS, Jan. 2017, Refereed, Not invited

Novel Therapeutic Role for Dipeptidyl Peptidase III in the Treatment of Hypertension
Xiaoling Pang; Akio Shimizu; Souichi Kurita; Dimitar P. Zankov; Keisuke Takeuchi; Mako Yasuda-Yamahara; Shinji Kume; Tetsuo Ishida; Hisakazu Ogita
HYPERTENSION, Sep. 2016, Refereed, Not invited

Enhanced Expression of Fibroblast Growth Factor Receptor 3 IIIc Promotes Human Esophageal Carcinoma Cell Proliferation
Nobuhiro Ueno; Akio Shimizu; Michiyuki Kanai; Yugo Iwaya; Shugo Ueda; Jun Nakayama; Misuzu Kurokawa Seo
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, Jan. 2016, Refereed, Not invited

VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells
Ayumi Yoshida; Akio Shimizu; Hirotsugu Asano; Tetsuya Kadonosono; Shinae Kizaka Kondoh; Elena Geretti; Akiko Mammoto; Michael Klagsbrun; Misuzu Kurokawa Seo
BIOLOGY OPEN, Sep. 2015, Refereed, Not invited

VEGF/VEGFR2 autocrine signaling stimulates metastasis in prostate cancer cells
Matthew Migliozzi; Yasuhiro Hida; Meetu Seth; Graham Brown; Joanne Kwan; Silvia Coma; Dipak Panigrahy; Rosalyn M. Adam; Jacqueline Banyard; Akio Shimizu; Diane R. Bielenberg
Current Angiogenesis, 01 Aug. 2015, Refereed, Not invited

Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas
Shokoufeh Shahrabi-Farahani; Lili Wang; Bernadette M. M. Zwaans; Jeans M. Santana; Akio Shimizu; Seiji Takashima; Michael Kreuter; Leigh Coultas; Patricia A. D'Amore; Jeffrey M. Arbeit; Lars A. Akslen; Diane R. Bielenberg
LABORATORY INVESTIGATION, Jul. 2014, Refereed, Not invited

Gleevec/imatinib, an ABL2 kinase inhibitor, protects tumor and endothelial cells from semaphorin-induced cytoskeleton collapse and loss of cell motility
Vera Procaccia; Hironao Nakayama; Akio Shimizu; Michael Klagsbrun
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2014, Refereed, Not invited

Netrin-1 Promotes Glioblastoma Cell Invasiveness and Angiogenesis by Multiple Pathways Including Activation of RhoA, Cathepsin B, and cAMP-response Element-binding Protein
Akio Shimizu; Hironao Nakayama; Priscilla Wang; Courtney Koenig; Tomoshige Akino; Johanna Sandlund; Silvia Coma; Joseph E. Italiano; Akiko Mammoto; Diane R. Bielenberg; Michael Klagsbrun
JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2013, Refereed, Not invited

Increased Smooth Muscle Contractility in Mice Deficient for Neuropilin 2
Diane R. Bielenberg; Abhishek Seth; Akio Shimizu; Kristine Pelton; Vivian Cristofaro; Aruna Ramachandran; Bernadette M. M. Zwaans; Cheng Chen; Ramaswamy Krishnan; Meetu Seth; Lin Huang; Seiji Takashima; Michael Klagsbrun; Maryrose P. Sullivan; Rosalyn M. Adam
AMERICAN JOURNAL OF PATHOLOGY, Aug. 2012, Refereed, Not invited

Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism
Hon-Kit Wong; Akio Shimizu; Nathaniel D. Kirkpatrick; Igor Garkavtsev; Annie W. Chan; Emmanuelle di Tomaso; Michael Klagsbrun; Rakesh K. Jain
NEOPLASIA, Feb. 2012, Refereed, Not invited

Hypoxia induces tumor and endothelial cell migration in a Semaphorin 3F-and VEGF-dependent manner via transcriptional repression of their common receptor Neuropilin 2
Silvia Coma; Akio Shimizu; Michael Klagsbrun
CELL ADHESION & MIGRATION, May 2011, Refereed, Not invited

A Mutated Soluble Neuropilin-2 B Domain Antagonizes Vascular Endothelial Growth Factor Bioactivity and Inhibits Tumor Progression
Elena Geretti; Laurens A. van Meeteren; Akio Shimizu; Andrew C. Dudley; Lena Claesson-Welsh; Michael Klagsbrun
MOLECULAR CANCER RESEARCH, Aug. 2010, Refereed, Not invited

Semaphorin 3E, an exception to the rule
Michael Klagsbrun; Akio Shimizu
JOURNAL OF CLINICAL INVESTIGATION, Aug. 2010, Refereed, Not invited

Id2 Promotes Tumor Cell Migration and Invasion through Transcriptional Repression of Semaphorin 3F
Silvia Coma; Dhara N. Amin; Akio Shimizu; Anna Lasorella; Antonio Iavarone; Michael Klagsbrun
CANCER RESEARCH, May 2010, Refereed, Not invited

ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells
Akio Shimizu; Akiko Mammoto; Joseph E. Italiano; Elke Pravda; Andrew C. Dudley; Donald E. Ingber; Michael Klagsbrun
JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2008, Refereed, Not invited

Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis
Elena Geretti; Akio Shimizu; Michael Klagsbrun
ANGIOGENESIS, Mar. 2008, Refereed, Not invited

Semaphorin-induced cytoskeletal collapse and repulsion of endothelial cells
Diane R. Bielenberg; Akio Shimizu; Michael Klagsbrun
ANGIOGENESIS: IN VITRO SYSTEMS, 2008, Refereed, Not invited

Site-directed mutagenesis in the b-neuropilin-2 domain selectively enhances its affinity to VEGF(165), but not to semaphorin 3F
Elena Geretti; Akio Shimizu; Peter Kurschat; Michael Klagsbrun
JOURNAL OF BIOLOGICAL CHEMISTRY, Aug. 2007, Refereed, Not invited

Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype
Diane R. Bielenberg; Yasuhiro Hida; Akio Shimizu; Arja Kaipainen; Michael Kreuter; Caroline Choi Kim; Michael Klagsbrun
Journal of Clinical Investigation, Nov. 2004, Refereed, Not invited

Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype.
Diane R Bielenberg; Yasuhiro Hida; Akio Shimizu; Arja Kaipainen; Michael Kreuter; Caroline Choi Kim; Michael Klagsbrun
The Journal of clinical investigation, Nov. 2004, Refereed, Not invited

FGFR3 isoforms have distinct functions in the regulation of growth and cell morphology
Akio Shimizu; Yuji Takashima; Misuzu Kurokawa-Seo
Biochemical and Biophysical Research Communications, 2002, Refereed, Not invited

選択的スプライシングにより生じるアシッドボックス欠損型と完全型FGFR3アイソフォームのFGF応答性の相違
清水 昭男; 多田 孝一郎; 宿南 知佐; 開 祐司; 黒川 勉; 真金 典子; 瀬尾 美鈴
生化学, Aug. 2001

A Novel Alternatively Spliced Fibroblast Growth Factor Receptor 3 Isoform Lacking the Acid Box Domain is Expressed during Chondrogenic Differentiation of ATDC5 Cells
Akio Shimizu; Kouichirou Tada; Chisa Shukunami; Yuji Hiraki; Tsutomu Kurokawa; Noriko Magane; Misuzu Kurokawa-Seo
Journal of Biological Chemistry, 06 Apr. 2001, Refereed, Not invited

Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs
Motoki Terada; Akio Shimizu; Nobuhiro Sato; Shin-Ichi Miyakaze; Hiroshi Katayama; Misuzu Kurokawa-Seo
Molecular Cell Biology Research Communications, 2001, Refereed, Not invited

ATDC5細胞の軟骨分化過程に発現するFGFR3 acid box欠損型と挿入型の機能の解析
清水 昭男; 多田 孝一郎; 開 祐司; 宿南 知佐; 瀬尾 美鈴
生化学, Aug. 1998

軟骨前駆細胞ATDC5に発現するacid box領域欠損型,挿入型FGFR3の塩基配列決定と軟骨分化時における発現様式の解析
清水 昭男; 多田 孝一郎; 開 祐司; 宿南 知佐; 瀬尾 美鈴
日本薬学会年会要旨集, Mar. 1998

心血管系におけるRhoAの新機能とその分子作用機序
清水昭男; MOLLA Md Rasel; SOH Joanne Ern Chi; 佐藤朗; 扇田久和
日本生化学会大会(Web), 2023

Role of transmembrane protein 168 mutations in Brugada syndrome by alteration in subcellular localization of αB-crystallin to modulate sodium channel Na v1.5 surface expression in cardiomyocytes
NGUYEN Le Kim Chil; SHIMIZU Akio; SATO Akira; OGITA Hisakazu
日本生化学会大会(Web), 2022

非ヒト霊長類モデルを活用したドキソルビシン誘発心筋症における心筋障害因子S100A8/9の同定とその阻害による心保護
佐藤朗; 佐藤朗; 清水昭男; 扇田久和
日本腫瘍循環器学会学術集会抄録集(Web), 2022

がんの浸潤・転移を促進させるepithelial membrane protein 1の分子作用機構
清水 昭男; 扇田 久和
生化学, Apr. 2020

糖尿病性腎症に対するジペプチジルペプチダーゼIIIの保護効果機構の解明
清水 昭男
医科学応用研究財団研究報告, Feb. 2020

糖尿病性腎症に対するジペプチジルペプチダーゼIIIの保護作用
Pang Xiaoling; 清水 昭男; Zankov Dimitar P.; 佐藤 朗; 石田 哲生; 扇田 久和
日本生化学会大会プログラム・講演要旨集, Sep. 2018

ジペプチジルペプチダーゼIIIのアンジオテンシンII分解活性と生体内での作用機序およびその治療応用への可能性
清水 昭男; 扇田 久和
生化学, 2017, Refereed, Not invited

Anosmin-1は嗅球の血管新生を誘導した
松島 章子; 清水 昭男; 浅野 弘嗣; 近藤 真菜美; 瀬尾 美鈴
日本生化学会大会プログラム・講演要旨集, Sep. 2016

Dipeptidyl peptidase IIIのアンジオテンシンII分解における生化学的特性の解明と新しい高血圧治療薬としての可能性
清水 昭男; Pang Xiaoling; 栗田 宗一; 竹内 圭介; 石田 哲夫; 扇田 久和
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

食道がんにおけるFGFR3IIIcアイソフォームのがん悪性化促進メカニズムの解析
上野 信洋; 清水 昭男; 金井 陸行; 岩谷 勇吾; 上田 修吾; 中山 淳; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

VEGF-A/NRP1シグナルの阻害はがん細胞の増殖と転移を抑制する
吉田 亜佑美; 清水 昭男; 上野 信洋; 浅野 弘嗣; 門之園 哲哉; 近藤 科江; Klagsbrun Michael; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

Anosmin-1の血管形成におけるシグナル伝達経路の解析
松島 章子; 清水 昭男; 近藤 真菜美; 浅野 弘嗣; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

カルマン症候群原因遺伝子産物Anosmin-1はニワトリ胚の嗅球と脳室においてNetrin-1と部分的に共局在する
木田 朱音; 安木 実悠; 徳村 脩人; 清水 昭男; 浅野 弘嗣; 石井 泰雄; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

誘引性軸索ガイダンス分子Anosmin-1はNetrin-1シグナルを阻害する
浅野 弘嗣; 竹内 祥人; 清水 昭男; 佐藤 直子; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

食道がんにおけるFGFR3IIIcアイソフォームのがん悪性化促進メカニズムの解析
瀬尾 美鈴; 上野 信洋; 清水 昭男; 曽和 穂菜美; 金井 陸行; 中山 淳; 板野 直樹
日本生化学会大会プログラム・講演要旨集, Oct. 2014

Kallmann症候群原因遺伝子産物Anosmin-1は神経成長円錐の形成を促進する
大嶋 朗; 岡本 沙矢香; 寺田 基剛; 森川 勇貴; 清水 昭男; 佐藤 直子; 緒方 勤; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010, Not refereed, Not invited

Kallmann症候群におけるFGFR1 Acid box変異体の神経突起伸長活性の解析
岡本 沙矢香; 大嶋 朗; 寺田 基剛; 清水 昭男; 佐藤 直子; 緒方 勤; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010

VEGF-AのNeuropilin-1を介した癌細胞の増殖促進
吉田 亜佑美; 寺田 基剛; 岡本 沙矢香; 清水 昭男; Klagsbrun Michael; 瀬尾 美鈴
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010

ヒト皮膚由来扁平上皮癌細胞における線維芽細胞増殖因子受容体3の発現亢進
寺田 基剛; 岡本 沙矢香; 大西 力; 上野 信洋; 清水 昭男; 金井 陸行; 瀬尾 美鈴
日本生化学会大会プログラム・講演要旨集, Sep. 2009

Tumor cells of high metastatic potential downregulate Semaphorin 3F by upregulating Id2
Silvia Coma; Dhara Amin; Akio Shimizu; Anna Lasorella; Antonio Iavarone; Michael Klagsbrun
CANCER RESEARCH, May 2009, Not refereed, Not invited

The Axon Guidance Mediators Semaphorins and Neuropilins Also Play A Role in Vascular and Tumor Biology
Michael Klagsbrun; Silvia Coma; Akio Shimizu
FASEB JOURNAL, Apr. 2009, Not refereed, Not invited

Fibroblast Growth Factor Receptor 3 induces Tumor Growth Throgh MAPK (ERK)-independent Signal Transduction Pathways in Skin Epithelial Cancer Cells
ONISHI Chikara; UENO Nobuhiro; KANAI Michiyuki; TERADA Motoki; SHIMIZU Akio; SEO Misuzu
Acta humanistica et scientifica universitatis Sangio Kyotiensis. Natural science series, Mar. 2006

Signal transduction of Fibroblast Growth Factor Receptor 3 in chondroprogenitor ATDC5 cells
ABE Shin-ichi; HAYASHI Eriko; ASHIYA Koichi; SHIMIZU Akiko; SEO Misuzu
Acta humanistica et scientifica universitatis Sangio Kyotiensis. Natural science series, Mar. 2006

FGFR3による軟骨前駆細胞の増殖抑制とMAPKの持続的活性化
林 恵里子; 安倍 慎一; 清水 昭男; 瀬尾 美鈴
京都産業大学先端科学技術研究所所報, Jul. 2004

線維芽細胞増殖因子による軟骨前駆細胞の増殖と分化誘導におけるシグナル伝達の機構
瀬尾 美鈴; 林 恵里子; 清水 昭男
京都産業大学先端科学技術研究所所報, Jul. 2003

Identification of Two Novel Alternatively Spliced Fibroblast Growth Factor Receptor 3 Isoforms : Their Biochemical and Biological Properties
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Acta humanistica et scientifica universitatis Sangio Kyotiensis. Natural science series, Mar. 2003

Signal Transduction Mediated by Fibroblast Growth Factor Receptor 3 Isoforms in Undifferentiated Chondrocytes
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モデル動物の作製と利用－循環器疾患2021 ＜上巻＞
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株式会社エル・アイ・シー, Sep. 2021

日本血管生物医学会

日本生化学会

がん分子標的治療学会

日本循環器学会

Analyses for molecular mechanisms of dipeptidyl peptidase III-targeted peptide that deteriorates diabetic kidney disease
Grant-in-Aid for Scientific Research (C)
Shiga University of Medical Science
01 Apr. 2021, 31 Mar. 2024

Novel cancer therapeutic target, epithelial membrane protein 1 (EMP1), investigation of the molecular mechanism inducing invasion and metastasis
Grant-in-Aid for Scientific Research (C)
Shiga University of Medical Science
01 Apr. 2017, 31 Mar. 2020